ES2125859T3 - Derivados de pirazoloacridona. - Google Patents

Derivados de pirazoloacridona.

Info

Publication number
ES2125859T3
ES2125859T3 ES91119896T ES91119896T ES2125859T3 ES 2125859 T3 ES2125859 T3 ES 2125859T3 ES 91119896 T ES91119896 T ES 91119896T ES 91119896 T ES91119896 T ES 91119896T ES 2125859 T3 ES2125859 T3 ES 2125859T3
Authority
ES
Spain
Prior art keywords
integer
lower alkyl
represents hydrogen
independently represents
pirazoloacridona
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91119896T
Other languages
English (en)
Inventor
Yukiteru Mimura
Yasushi Shida
Masaji Kasai
Tadashi Ashizawa
Katsushige Gomi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of ES2125859T3 publication Critical patent/ES2125859T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTAN DERIVADOS DE LA PIRAZOLOACRIDONA REPRESENTADOS POR LA FORMULA (I) EN DONDE: CADA UNA DE R ELEVADO 1A, R ELEVADO 1B, R ELEVADO 1C Y R ELEVADO 1D REPRESENTAN INDEPENDIENTEMENTE HIDROGENO, ALQUIL INFERIOR, -(CH SUB 2) SUB P-X EN DONDE P REPRESENTA UN ENTERO ENTRE 1 Y 6, Y X REPRESENTA HIDROXIDO, ALCOXIDO INFERIOR O -NR*R* DONDE CADA R* Y R* REPRESENTAN INDEPENDIENTEMENTE HIDROGENO, ALQUIL INFERIOR O -(CH SUB 2) SUB M-Y EN DONDE M REPRESENTA UN ENTERO ENTRE 1 Y 6, E Y REPRESENTA HIDROXIDO, ALCOXIDO INFERIOR O -NR ELEVADO 3A R ELEVADO 3B EN DONDE CADA UNA DE R ELEVADO 3A Y R ELEVADO 3B REPRESENTAN INDEPENDIENTEMENTE HIDROGENO O ALQUIL INFERIOR O R* Y R* FORMAN UN GRUPO HETEROCICLICO JUNTO CON EL ATOMO DE NITROGENO ADYACENTE, O BIEN -CH[(CH SUB 2) SUB NOH] SUB 2 DONDE N REPRESENTA UN ENTERO ENTRE 1 Y 5; ASI MISMO SE REPRESENTAN LAS SALES FARMACEUTICAMENTE ACEPTABLES DE LOS MENCIONADOS DERIVADOS.
ES91119896T 1990-11-22 1991-11-21 Derivados de pirazoloacridona. Expired - Lifetime ES2125859T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP32043890 1990-11-22

Publications (1)

Publication Number Publication Date
ES2125859T3 true ES2125859T3 (es) 1999-03-16

Family

ID=18121451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91119896T Expired - Lifetime ES2125859T3 (es) 1990-11-22 1991-11-21 Derivados de pirazoloacridona.

Country Status (7)

Country Link
US (1) US5220026A (es)
EP (1) EP0487097B1 (es)
JP (1) JPH0676409B2 (es)
AT (1) ATE172200T1 (es)
DE (1) DE69130356T2 (es)
ES (1) ES2125859T3 (es)
HK (1) HK1000706A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1122256A4 (en) * 1998-10-14 2002-01-02 Kyowa Hakko Kogyo Kk PROCESS FOR STABILIZING AQUEOUS SOLUTION BASED ON PYRAZOLOACRIDONE DERIVATIVE
WO2004094423A1 (ja) * 2003-04-24 2004-11-04 Kyowa Hakko Kogyo Co., Ltd. ピラゾロアクリドン誘導体の製造法およびその合成中間体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS583067B2 (ja) * 1974-10-30 1983-01-19 三菱化学株式会社 ゴウセイセンイルイノ センシヨクホウホウ
JPS5978190A (ja) * 1982-10-28 1984-05-04 Kyowa Hakko Kogyo Co Ltd 新規物質ａｘ―２
JP2795460B2 (ja) * 1988-06-20 1998-09-10 協和醗酵工業株式会社 ピラゾロアクリドン誘導体

Also Published As

Publication number Publication date
DE69130356D1 (de) 1998-11-19
HK1000706A1 (en) 2000-03-17
US5220026A (en) 1993-06-15
JPH0676409B2 (ja) 1994-09-28
JPH051064A (ja) 1993-01-08
DE69130356T2 (de) 1999-06-10
EP0487097B1 (en) 1998-10-14
EP0487097A1 (en) 1992-05-27
ATE172200T1 (de) 1998-10-15

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