ES2066564T3 - Derivados de n-2-clorobencil-2-oxo y n-2-clorobencil-2,2-dioxo-1,2,3-oxatiazolidina, su preparacion y sintesis de derivados de tieno(3,2-c)piridina de estos. - Google Patents

Derivados de n-2-clorobencil-2-oxo y n-2-clorobencil-2,2-dioxo-1,2,3-oxatiazolidina, su preparacion y sintesis de derivados de tieno(3,2-c)piridina de estos.

Info

Publication number
ES2066564T3
ES2066564T3 ES92400233T ES92400233T ES2066564T3 ES 2066564 T3 ES2066564 T3 ES 2066564T3 ES 92400233 T ES92400233 T ES 92400233T ES 92400233 T ES92400233 T ES 92400233T ES 2066564 T3 ES2066564 T3 ES 2066564T3
Authority
ES
Spain
Prior art keywords
chlorobencil
dioxo
oxo
derivatives
thyeno
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92400233T
Other languages
English (en)
Inventor
Gary F Cooper
Keith E Mccarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24599509&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2066564(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of ES2066564T3 publication Critical patent/ES2066564T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/02—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
    • C07D291/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LOS COMPUESTOS DE LA FORMULA: EN DONDE: A ES OXO O DIOXO; R ELEVADO 1, R (AL CUADRADO) Y R ELEVADO 3 SON INDEPENDIENTES HIDROGENO O ALQUILO INFERIOR DE UNO A SEIS ATOMOS DE CARBONO; R ELEVADO 4, R ELEVADO 5, R ELEVADO 6 Y R ELEVADO 7 SON INDEPENDIENTEMENTE HIDROGENO, ALQUILO INFERIOR DE UNO A SEIS ATOMOS DE CARBONO, ALCOXI, ACILO O HALO; SON CONVERTIDOS DE MANERA VENTAJOSA EN DERIVADOS DE TIENO[3, 2-C]PIRIDINA Y LAS SALES FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS, EN PARTICULAR HIDROCLORURO DE TICLOPIDINA.
ES92400233T 1991-01-31 1992-01-29 Derivados de n-2-clorobencil-2-oxo y n-2-clorobencil-2,2-dioxo-1,2,3-oxatiazolidina, su preparacion y sintesis de derivados de tieno(3,2-c)piridina de estos. Expired - Lifetime ES2066564T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/648,117 US5342953A (en) 1991-01-31 1991-01-31 N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom

Publications (1)

Publication Number Publication Date
ES2066564T3 true ES2066564T3 (es) 1995-03-01

Family

ID=24599509

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92400233T Expired - Lifetime ES2066564T3 (es) 1991-01-31 1992-01-29 Derivados de n-2-clorobencil-2-oxo y n-2-clorobencil-2,2-dioxo-1,2,3-oxatiazolidina, su preparacion y sintesis de derivados de tieno(3,2-c)piridina de estos.

Country Status (13)

Country Link
US (2) US5342953A (es)
EP (1) EP0497695B1 (es)
JP (1) JP3091006B2 (es)
KR (1) KR0171221B1 (es)
AT (1) ATE115572T1 (es)
CA (1) CA2060401C (es)
DE (1) DE69200862T2 (es)
DK (1) DK0497695T3 (es)
ES (1) ES2066564T3 (es)
GR (1) GR3015398T3 (es)
HU (1) HU216796B (es)
IE (1) IE65967B1 (es)
PL (1) PL168815B1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342953A (en) * 1991-01-31 1994-08-30 Syntex (U.S.A.) Inc. N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom
ES2180638T3 (es) 1994-06-03 2003-02-16 Wyeth John & Brother Ltd Nuevos procedimientos e intermediarios para la preparacion de derivados de piperazina.
US6043368A (en) 1996-09-04 2000-03-28 Poli Industria Chimica, S.P.A. Method of making thieno-pyridine derivatives
CN101613310A (zh) * 2002-04-10 2009-12-30 艾普辛特姆有限责任公司 胺立体异构体的制备方法
CN105601644A (zh) * 2015-12-31 2016-05-25 苏州弘森药业有限公司 一种合成盐酸噻氯匹定的新方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4127580A (en) * 1975-02-07 1978-11-28 Parcor Process for the preparation of thieno-pyridine derivatives
FR2376860A1 (fr) * 1977-01-07 1978-08-04 Parcor Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique
US5130432A (en) * 1990-12-21 1992-07-14 Syntex (U.S.A.) Inc. Process for preparing cyclic amines and intermediate products thereof
US5342953A (en) * 1991-01-31 1994-08-30 Syntex (U.S.A.) Inc. N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom

Also Published As

Publication number Publication date
PL293351A1 (en) 1992-10-19
KR920014790A (ko) 1992-08-25
PL168815B1 (pl) 1996-04-30
ATE115572T1 (de) 1994-12-15
HUT63426A (en) 1993-08-30
HU216796B (hu) 1999-08-30
JPH0597830A (ja) 1993-04-20
EP0497695B1 (en) 1994-12-14
HU9200283D0 (en) 1992-04-28
DE69200862D1 (de) 1995-01-26
US5516910A (en) 1996-05-14
IE65967B1 (en) 1995-11-29
EP0497695A1 (en) 1992-08-05
US5342953A (en) 1994-08-30
KR0171221B1 (ko) 1999-02-01
DK0497695T3 (da) 1995-05-15
GR3015398T3 (en) 1995-06-30
JP3091006B2 (ja) 2000-09-25
CA2060401C (en) 2004-07-06
DE69200862T2 (de) 1995-05-11
IE920314A1 (en) 1992-07-29
CA2060401A1 (en) 1992-08-01

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