ES2124708T3 - Nuevo procedimiento para preparar 2'-(dietilamino)rifamicina p (p/dea). - Google Patents

Nuevo procedimiento para preparar 2'-(dietilamino)rifamicina p (p/dea).

Info

Publication number
ES2124708T3
ES2124708T3 ES92100407T ES92100407T ES2124708T3 ES 2124708 T3 ES2124708 T3 ES 2124708T3 ES 92100407 T ES92100407 T ES 92100407T ES 92100407 T ES92100407 T ES 92100407T ES 2124708 T3 ES2124708 T3 ES 2124708T3
Authority
ES
Spain
Prior art keywords
rifamycin
dea
diethylamine
prepare
new procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92100407T
Other languages
English (en)
Inventor
Gianbattista Panzone
Anacleto Gianantonio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Application granted granted Critical
Publication of ES2124708T3 publication Critical patent/ES2124708T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

ESTA INVENCION DESCRIBE UN NUEVO PROCESO EN UN SOLO ENVASE PARA PREPARAR 2''-(DIETILAMINO) RIFAMICINA P Y SU DERIVADO 25-DESACETILO DE LA FORMULA (I) QUE CONSISTE EN LA CIELACION DE 3-BROMORIFAMICINA S O SU DERIVADO 25-DESACETILO DE LA FORMULA (II), DISUELTO EN DIMETILFORMAMIDA, CON 1,1-DIETILHIOUREA Y REDUCIR, SIN AISLAMIENTO, EL INTERMEDIARIO OBTENIDO 1,2-QUINONIMINA DE LA FORMULA (III) CON UN AGENTE DE REDUCCION SUAVE.
ES92100407T 1991-01-28 1992-01-13 Nuevo procedimiento para preparar 2'-(dietilamino)rifamicina p (p/dea). Expired - Lifetime ES2124708T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91101037 1991-01-28

Publications (1)

Publication Number Publication Date
ES2124708T3 true ES2124708T3 (es) 1999-02-16

Family

ID=8206332

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92100407T Expired - Lifetime ES2124708T3 (es) 1991-01-28 1992-01-13 Nuevo procedimiento para preparar 2'-(dietilamino)rifamicina p (p/dea).

Country Status (14)

Country Link
US (1) US5378837A (es)
EP (1) EP0497125B1 (es)
JP (1) JP3154783B2 (es)
KR (1) KR920014819A (es)
AT (1) ATE174336T1 (es)
CA (1) CA2059999C (es)
DE (1) DE69227790T2 (es)
DK (1) DK0497125T3 (es)
ES (1) ES2124708T3 (es)
GR (1) GR3029624T3 (es)
HU (1) HU208697B (es)
IE (1) IE920235A1 (es)
IL (1) IL100642A (es)
ZA (1) ZA92537B (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1470426A (en) * 1974-08-30 1977-04-14 Lepetit Spa Rifamycins
IT1053787B (it) * 1974-10-29 1981-10-10 Pastori A Macrolidi azotati e loro preparazione
GB1523198A (en) * 1976-05-28 1978-08-31 Lepetit Spa Thiazolo-rifamycin derivatives
GB1523199A (en) * 1976-05-28 1978-08-31 Lepetit Spa Rifamycin sv derivatives
CH629212A5 (it) * 1976-10-18 1982-04-15 Erba Farmitalia Procedimento per la preparazione di composti di rifamicina.
IT1090759B (it) * 1977-11-29 1985-06-26 Alfa Farmaceutici Spa Procedimento per la preparazione di 3 iodio e 3 bromo rifamicina s
GB8531887D0 (en) * 1985-12-30 1986-02-05 Lepetit Spa Rifamycin sv derivatives

Also Published As

Publication number Publication date
IL100642A (en) 1995-11-27
DE69227790D1 (de) 1999-01-21
IL100642A0 (en) 1992-09-06
DE69227790T2 (de) 1999-06-10
GR3029624T3 (en) 1999-06-30
IE920235A1 (en) 1992-07-29
HU208697B (en) 1993-12-28
HUT61315A (en) 1992-12-28
DK0497125T3 (da) 1999-08-16
AU1033092A (en) 1992-07-30
US5378837A (en) 1995-01-03
HU9200255D0 (en) 1992-05-28
JP3154783B2 (ja) 2001-04-09
ATE174336T1 (de) 1998-12-15
AU650509B2 (en) 1994-06-23
KR920014819A (ko) 1992-08-25
CA2059999C (en) 2001-09-25
ZA92537B (en) 1992-12-30
CA2059999A1 (en) 1992-07-29
EP0497125B1 (en) 1998-12-09
EP0497125A1 (en) 1992-08-05
JPH04346990A (ja) 1992-12-02

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