ES2124404T3 - Forma solida de administracion de 5-mononitrato de isosorbida. - Google Patents

Forma solida de administracion de 5-mononitrato de isosorbida.

Info

Publication number
ES2124404T3
ES2124404T3 ES94915104T ES94915104T ES2124404T3 ES 2124404 T3 ES2124404 T3 ES 2124404T3 ES 94915104 T ES94915104 T ES 94915104T ES 94915104 T ES94915104 T ES 94915104T ES 2124404 T3 ES2124404 T3 ES 2124404T3
Authority
ES
Spain
Prior art keywords
administration
mononitrate
solid form
isosorbida
lacquer layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94915104T
Other languages
English (en)
Inventor
Egmond Cornelia Alida Mari Van
Andre Pullen
Jong Sibo Wytse De
Jong Adrianus Petrus De
Jan Bron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Application granted granted Critical
Publication of ES2124404T3 publication Critical patent/ES2124404T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DA A CONOCER UNA FORMA DE ADMINISTRACION ORAL SOLIDA PARA 5 - MONONITRATO ISOSORBIDE CON LIBERACION CONTROLADA, INDEPENDIENTE DE PH DE SUSTANCIAS ACTIVA EN EL TRACTO INTESTINALESTOMAGO EN FORMA DE PELET SOMETIDOS A CAPA DE RECUBRIMIENTO DE LACA DE ALARGAMIENTO DE UNA CESION CON UNA CAPA DE DEPOSITO, QUE SE CARACTERIZA DE TAL MODO, QUE LA CELULOSA ETILO DE LA CAPA DE LACA Y EL POLIMETACRILATO SE ENCUENTRAN EN UNA RELACION EN PESO DE 3 : 1 HASTA 3 : 2. LA NUEVA FORMA DE ADMINISTRACION SE CARACTERIZA POR UNA ELABORACION MENOS COSTOSA.
ES94915104T 1993-04-27 1994-04-23 Forma solida de administracion de 5-mononitrato de isosorbida. Expired - Lifetime ES2124404T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4313726A DE4313726A1 (de) 1993-04-27 1993-04-27 Feste Darreichungsform

Publications (1)

Publication Number Publication Date
ES2124404T3 true ES2124404T3 (es) 1999-02-01

Family

ID=6486477

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94915104T Expired - Lifetime ES2124404T3 (es) 1993-04-27 1994-04-23 Forma solida de administracion de 5-mononitrato de isosorbida.

Country Status (8)

Country Link
US (1) US5869094A (es)
EP (1) EP0695176B1 (es)
JP (1) JPH08509480A (es)
AT (1) ATE171371T1 (es)
AU (1) AU6647794A (es)
DE (2) DE4313726A1 (es)
ES (1) ES2124404T3 (es)
WO (1) WO1994025010A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5310898A (en) * 1996-12-20 1998-07-17 Dumex-Alpharma A/S Release-controlled coated tablets
US6602521B1 (en) * 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US6274162B1 (en) 2000-01-14 2001-08-14 Bpsi Holdings, Inc. Elegant film coating system
EP1708684A2 (en) 2003-09-26 2006-10-11 Alza Corporation Drug coating providing high drug loading and methods for providing the same
WO2007016948A1 (de) 2005-08-10 2007-02-15 Add Advanced Drug Delivery Technologies Ltd. Orales präparat mit kontrollierter freisetzung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1187750B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di compresse,anche a rilascio prolungato,di iscsorbide-5-mononitrato stabilizzato e formulazioni cosi' ottenute
JPS6327424A (ja) * 1986-07-17 1988-02-05 Shionogi & Co Ltd 徐放性製剤およびその製造法
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
WO1992001446A1 (en) * 1990-07-20 1992-02-06 Aps Research Limited Sustained-release formulations

Also Published As

Publication number Publication date
JPH08509480A (ja) 1996-10-08
WO1994025010A1 (de) 1994-11-10
DE4313726A1 (de) 1994-11-03
ATE171371T1 (de) 1998-10-15
AU6647794A (en) 1994-11-21
EP0695176A1 (de) 1996-02-07
DE59406979D1 (de) 1998-10-29
US5869094A (en) 1999-02-09
EP0695176B1 (de) 1998-09-23

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