ES2118945T3 - Derivados de melamina utilizados en el tratamiento del cancer. - Google Patents

Derivados de melamina utilizados en el tratamiento del cancer.

Info

Publication number
ES2118945T3
ES2118945T3 ES93907928T ES93907928T ES2118945T3 ES 2118945 T3 ES2118945 T3 ES 2118945T3 ES 93907928 T ES93907928 T ES 93907928T ES 93907928 T ES93907928 T ES 93907928T ES 2118945 T3 ES2118945 T3 ES 2118945T3
Authority
ES
Spain
Prior art keywords
pct
cancer
treatment
derivatives used
melamine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93907928T
Other languages
English (en)
Inventor
Michael Jarman
Helen Mary Coley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cancer Research Campaign Technology Ltd
Original Assignee
Cancer Research Campaign Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Campaign Technology Ltd filed Critical Cancer Research Campaign Technology Ltd
Application granted granted Critical
Publication of ES2118945T3 publication Critical patent/ES2118945T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

EN LA PRESENTE INVENCION SE PRESENTAN COMPUESTOS DE LA FORMULA GENERAL (I) EN LA QUE R1, QUE PUEDE SER IGUAL O DIFERENTE, ES HIDROGENO, ALQUILO O UN GRUPO CAPTADOR DE ELECTRONES, R2 ES HIDROGENO, ALQUILO O UN GRUPO ORGANICO CAPTADOR DE ELECTRONES. LOS COMPUESTOS SON ANALOGOS DEL TRIMELAMOL QUE PRESENTAN UNA ACTIVIDAD COMPARABLE PERO TIENEN UNA MAYOR ESTABILIDAD Y SON UTILES COMO AGENTES CONTRA EL CANCER EN PARTICULAR CONTRA LOS CARCINOMAS OVARICOS.
ES93907928T 1992-03-27 1993-03-26 Derivados de melamina utilizados en el tratamiento del cancer. Expired - Lifetime ES2118945T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929206768A GB9206768D0 (en) 1992-03-27 1992-03-27 New compounds for use in the treatment of cancer

Publications (1)

Publication Number Publication Date
ES2118945T3 true ES2118945T3 (es) 1998-10-01

Family

ID=10713003

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93907928T Expired - Lifetime ES2118945T3 (es) 1992-03-27 1993-03-26 Derivados de melamina utilizados en el tratamiento del cancer.

Country Status (10)

Country Link
US (2) US5534625A (es)
EP (1) EP0632805B1 (es)
JP (1) JPH07505380A (es)
AT (1) ATE168105T1 (es)
AU (1) AU676677B2 (es)
DE (1) DE69319590T2 (es)
DK (1) DK0632805T3 (es)
ES (1) ES2118945T3 (es)
GB (1) GB9206768D0 (es)
WO (1) WO1993020056A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0787424B2 (ja) * 1993-06-30 1995-09-20 日本電気株式会社 バースト信号送信システム
CA2241525A1 (en) * 1995-12-27 1997-07-10 Nissan Chemical Industries, Ltd. Methods for modifying 1,3,5-triazine derivatives
EP1053230A1 (en) * 1998-01-13 2000-11-22 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
US6262053B1 (en) * 1999-06-23 2001-07-17 Parker Hughes Institute Melamine derivatives as potent anti-cancer agents
US6645964B1 (en) * 1999-11-29 2003-11-11 Aventis Pharma S.A. Chemical derivatives and their application as antitelomerase agent
FR2801588B1 (fr) * 1999-11-29 2002-03-01 Aventis Pharma Sa Derives chimiques et leur application comme agent antitelomerase
IL149402A0 (en) * 1999-11-29 2002-11-10 Aventis Pharma Sa Arylamine derivatives and their use as anti-telomerase agent
US6858608B2 (en) 2001-01-09 2005-02-22 Aventis Pharma S.A. Chemical derivatives and their application as antitelomerase agents
FR2819255B1 (fr) * 2001-01-09 2003-02-28 Aventis Pharma Sa Derives chimiques et leur application comme agent antitelomerase
US6887873B2 (en) * 2001-03-23 2005-05-03 Aventis Pharma S.A. Triazine derivatives and their application as antitelomerase agents
CO5380035A1 (es) * 2001-03-23 2004-03-31 Aventis Pharma Sa Derivados quimicos y su aplicacion como agente antitelomerasa
FR2822468B1 (fr) * 2001-03-23 2008-06-20 Aventis Pharma Sa Derives chimiques et leur application comme agent anti-telomerase
US20070232572A1 (en) * 2003-02-07 2007-10-04 Aventis Pharma S.A. Chemical derivatives as antitelomerase agents which bind specifically to the G-quadruplex DNA structures and their application as a specific anticancer agent
CN101684115B (zh) * 2008-09-26 2011-12-21 上海医药工业研究院 4-(5-((2-(4-吗啉基-6-苯氨基-1,3,5-三嗪-2-基)亚肼基)甲基)呋喃-2-基)苯甲酸、其制备方法及用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2566225A (en) * 1951-08-28 Process for preparing substituted
US2476548A (en) * 1949-07-19 Preparation of triazinfliufitmlts
US2420157A (en) * 1943-02-12 1947-05-06 American Cyanamid Co Resin finishing of textiles
US2485059A (en) * 1944-05-06 1949-10-18 Monsanto Chemicals Melamine condensation product
US2476127A (en) * 1946-06-07 1949-07-12 American Cyanamid Co Reaction product of a polymethylol melamine and an aromatic amine
US2565194A (en) * 1947-03-27 1951-08-21 American Cyanamid Co Chlorotriazine resins and process of making the same
US2537131A (en) * 1947-07-18 1951-01-09 American Cyanamid Co Continuous process for the preparation of alkylated alkylol melamine
US2520619A (en) * 1948-10-05 1950-08-29 American Cyanamid Co Preparation of triethylenemelamine
US2709693A (en) * 1950-12-04 1955-05-31 Ciba Ltd Etherified condensation products of formaldehyde with amino-1:3:5-triazines containing at least two aminogroups
US2781553A (en) * 1953-03-13 1957-02-19 American Cyanamid Co Spray molding process
GB9106170D0 (en) * 1991-03-22 1991-05-08 Jarman Michael New compounds for use in the treatment of cancer

Also Published As

Publication number Publication date
ATE168105T1 (de) 1998-07-15
DE69319590D1 (de) 1998-08-13
US5534625A (en) 1996-07-09
EP0632805A1 (en) 1995-01-11
DE69319590T2 (de) 1998-11-12
JPH07505380A (ja) 1995-06-15
DK0632805T3 (da) 1999-04-19
US5854244A (en) 1998-12-29
GB9206768D0 (en) 1992-05-13
EP0632805B1 (en) 1998-07-08
AU676677B2 (en) 1997-03-20
WO1993020056A1 (en) 1993-10-14
AU3894293A (en) 1993-11-08

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