ES2101728T3 - Determinacion no invasiva de la concentracion de glucosa en el cuerpo de un paciente. - Google Patents

Determinacion no invasiva de la concentracion de glucosa en el cuerpo de un paciente.

Info

Publication number
ES2101728T3
ES2101728T3 ES91311421T ES91311421T ES2101728T3 ES 2101728 T3 ES2101728 T3 ES 2101728T3 ES 91311421 T ES91311421 T ES 91311421T ES 91311421 T ES91311421 T ES 91311421T ES 2101728 T3 ES2101728 T3 ES 2101728T3
Authority
ES
Spain
Prior art keywords
radiation
patient
function
scattered
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91311421T
Other languages
English (en)
Inventor
Russell H Barnes
Jimmy W Brasch Sr
David L Purdy
William D Lougheed
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diasense Inc
Original Assignee
Diasense Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diasense Inc filed Critical Diasense Inc
Application granted granted Critical
Publication of ES2101728T3 publication Critical patent/ES2101728T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/42Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
    • G01J3/433Modulation spectrometry; Derivative spectrometry

Abstract

UNA RADIACION CERCANA AL INFRARROJO SOBRE UNA BANDA LIMITADA DE LONGITUDES DE ONDA DE ALREDEDOR DE 1660 NANOMETROS SE PROYECTA SOBRE UNA PARTE (31) DEL CUERPO, POR EJEMPLO LA OREJA DEL PACIENTE. LA RADIACION RESULTANTE EMITIDA POR ESA PARTE DEL CUERPO, TANTO LA RADIACION DISPERSADA DESDE LA PARTE COMO LA TRANSMITIDA DESPUES DE LA ABSORCION Y DISPERSA POR LA PARTE DEL CUERPO, SE PROCESA PARA DEDUCIR UNA EXPRESION DE LA RADIACION RESULTANTE COMO FUNCION DE LA LONGITUD DE ONDA. LA SEGUNDA DERIVADA DE ESTA FUNCION SOBRE UNA BANDA MUY ESTRECHA DE ESTA FUNCION ENTRE 1640 Y 1670 NANOMETROS SE EXPANDE Y SE DETERMINA LA CONCENTRACION DE GLUCOSA A PARTIR DE LA MAGNITUD, O INTENSIDAD DE LA RADIACION DISPERSADA O TRANSMITIDA EN EL PUNTO MAXIMO O MINIMO DE ESTA DERIVADA. TAMBIEN SE PRESENTA UN APARATO PARA LA DETERMINACION NO INVASIVA DE LA CONCENTRACION DE GLUCOSA EN UN PACIENTE. LA RADIACION CERCANA DEL INFRARROJO SE TRANSMITE A TRAVES DE UN PRIMER CONDUCTOR DE LA RADIACION EN FORMA DE VIBRA OPTICA (29) HASTA LA SUPERFICIE EXTERIOR DE UNA PARTE (31) DEL CUERPO DEL PACIENTE, PENETRANDO AL INTERIOR DE ESA PARTE. UN SEGUNDO CONDUCTOR DE FIBRA OPTICA (33) TRANSMITE LA RADIACION RESULTANTE EMITIDA DESDE LA PARTE HASTA UN MEDIO DE PROCESAMIENTO DE DATOS (23) QUE PRODUCE LA SEGUNDA DERIVADA DESEADA COMO FUNCION DE LA LONGITUD DE ONDA DE LA RADIACION INCIDENTE. EL PROCESADOR INCLUYE UN ANALIZADOR DE ESPECTROS (21) QUE PRODUCE UN ESPECTRO DE LA RADIACION RESULTANTE.
ES91311421T 1990-01-30 1991-12-09 Determinacion no invasiva de la concentracion de glucosa en el cuerpo de un paciente. Expired - Lifetime ES2101728T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/482,792 US5070874A (en) 1990-01-30 1990-01-30 Non-invasive determination of glucose concentration in body of patients
CA002056868A CA2056868C (en) 1990-01-30 1991-12-03 Non-invasive determination of glucose concentration in body of patient
AU88392/91A AU643855B2 (en) 1990-01-30 1991-12-04 Non-invasive determination of glucose concentration in body of patient
EP91311421A EP0548418B1 (en) 1990-01-30 1991-12-09 Non-invasive determination of glucose concentration in body of patient

Publications (1)

Publication Number Publication Date
ES2101728T3 true ES2101728T3 (es) 1997-07-16

Family

ID=27424036

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91311421T Expired - Lifetime ES2101728T3 (es) 1990-01-30 1991-12-09 Determinacion no invasiva de la concentracion de glucosa en el cuerpo de un paciente.

Country Status (8)

Country Link
US (1) US5070874A (es)
EP (1) EP0548418B1 (es)
AT (1) ATE152338T1 (es)
AU (1) AU643855B2 (es)
CA (1) CA2056868C (es)
DE (1) DE69125942T2 (es)
DK (1) DK0548418T3 (es)
ES (1) ES2101728T3 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020152380A1 (es) 2019-01-22 2020-07-30 Universidad De Sevilla Dispositivo portable y método para la estimación no invasiva del nivel de glucosa en sangre

Families Citing this family (221)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5237178A (en) * 1990-06-27 1993-08-17 Rosenthal Robert D Non-invasive near-infrared quantitative measurement instrument
US5204532A (en) * 1989-01-19 1993-04-20 Futrex, Inc. Method for providing general calibration for near infrared instruments for measurement of blood glucose
US6066847A (en) * 1989-01-19 2000-05-23 Futrex Inc. Procedure for verifying the accuracy of non-invasive blood glucose measurement instruments
CA2028261C (en) * 1989-10-28 1995-01-17 Won Suck Yang Non-invasive method and apparatus for measuring blood glucose concentration
DE3938759A1 (de) * 1989-11-23 1991-05-29 Philips Patentverwaltung Nichtinvasive oximeteranordnung
US5070874A (en) * 1990-01-30 1991-12-10 Biocontrol Technology, Inc. Non-invasive determination of glucose concentration in body of patients
US5246004A (en) * 1990-02-02 1993-09-21 Angiomedics Ii, Inc. Infrared cholesterol sensor
US5222496A (en) * 1990-02-02 1993-06-29 Angiomedics Ii, Inc. Infrared glucose sensor
US5222495A (en) * 1990-02-02 1993-06-29 Angiomedics Ii, Inc. Non-invasive blood analysis by near infrared absorption measurements using two closely spaced wavelengths
US5574283A (en) * 1990-06-27 1996-11-12 Futrex, Inc. Non-invasive near-infrared quantitative measurement instrument
US5324979A (en) * 1990-09-26 1994-06-28 Futrex, Inc. Method and means for generating synthetic spectra allowing quantitative measurement in near infrared measuring instruments
US5219400A (en) * 1991-06-11 1993-06-15 The United States Of America As Represented By The Secretary Of The Army Noninvasive method for quantitation of oxyhemoglobin saturation by near-infrared reflectance spectrophotometry
JPH05228098A (ja) * 1992-02-20 1993-09-07 Asahi Optical Co Ltd 測温内視鏡
EP0630203B1 (en) * 1992-02-28 2002-07-31 CADELL, Theodore E. Non-invasive device and method for determining concentrations of various components of blood or tissue
US5377674A (en) * 1992-05-08 1995-01-03 Kuestner; J. Todd Method for non-invasive and in-vitro hemoglobin concentration measurement
US5818048A (en) * 1992-07-15 1998-10-06 Optix Lp Rapid non-invasive optical analysis using broad bandpass spectral processing
US5434412A (en) * 1992-07-15 1995-07-18 Myron J. Block Non-spectrophotometric measurement of analyte concentrations and optical properties of objects
US5424545A (en) * 1992-07-15 1995-06-13 Myron J. Block Non-invasive non-spectrophotometric infrared measurement of blood analyte concentrations
US5433197A (en) * 1992-09-04 1995-07-18 Stark; Edward W. Non-invasive glucose measurement method and apparatus
US5762609A (en) * 1992-09-14 1998-06-09 Sextant Medical Corporation Device and method for analysis of surgical tissue interventions
US5746210A (en) * 1993-02-26 1998-05-05 David A. Benaron Device and method for detection, localization, and characterization of inhomogeneities in turbid media
US5772597A (en) * 1992-09-14 1998-06-30 Sextant Medical Corporation Surgical tool end effector
US6172743B1 (en) 1992-10-07 2001-01-09 Chemtrix, Inc. Technique for measuring a blood analyte by non-invasive spectrometry in living tissue
US5379764A (en) * 1992-12-09 1995-01-10 Diasense, Inc. Non-invasive determination of analyte concentration in body of mammals
US5360004A (en) * 1992-12-09 1994-11-01 Diasense, Inc. Non-invasive determination of analyte concentration using non-continuous radiation
US5398681A (en) * 1992-12-10 1995-03-21 Sunshine Medical Instruments, Inc. Pocket-type instrument for non-invasive measurement of blood glucose concentration
DE4242083C2 (de) * 1992-12-14 1995-07-20 Marbach Hermann Dipl Ing Sensorvorrichtung zur reproduzierbaren, nichtinvasiven Messung der Blutglucose
US5515847A (en) * 1993-01-28 1996-05-14 Optiscan, Inc. Self-emission noninvasive infrared spectrophotometer
US5615672A (en) * 1993-01-28 1997-04-01 Optiscan, Inc. Self-emission noninvasive infrared spectrophotometer with body temperature compensation
US5447159A (en) * 1993-02-03 1995-09-05 Massachusetts Institute Of Technology Optical imaging for specimens having dispersive properties
US5487384A (en) * 1993-02-25 1996-01-30 Blue Marble Research, Inc. Kinematic assay of plasma glucose concentration without blood sampling
US5987346A (en) 1993-02-26 1999-11-16 Benaron; David A. Device and method for classification of tissue
AU6186494A (en) * 1993-05-07 1994-11-10 Diasense, Inc. Non-invasive determination of analyte concentration using non-continuous radiation
US5343045A (en) * 1993-06-11 1994-08-30 Ontario Hydro Method and device for measuring moisture content
US5383452A (en) * 1993-07-01 1995-01-24 Buchert; Janusz Method, apparatus and procedure for non-invasive monitoring blood glucose by measuring the polarization ratio of blood luminescence
DE4339067A1 (de) * 1993-11-16 1995-05-18 Jenoptik Jena Gmbh Verfahren und Anordnung zur nichtinvasiven, transkutanen Bestimmung von Stoffkonzentrationen in Körperflüssigkeit oder Gewebe des Menschen
US5459317A (en) * 1994-02-14 1995-10-17 Ohio University Method and apparatus for non-invasive detection of physiological chemicals, particularly glucose
US5562729A (en) * 1994-11-01 1996-10-08 Biocontrol Technology, Inc. Heart valve
US5743262A (en) * 1995-06-07 1998-04-28 Masimo Corporation Blood glucose monitoring system
SG38866A1 (en) * 1995-07-31 1997-04-17 Instrumentation Metrics Inc Liquid correlation spectrometry
US5655530A (en) * 1995-08-09 1997-08-12 Rio Grande Medical Technologies, Inc. Method for non-invasive blood analyte measurement with improved optical interface
US6240306B1 (en) 1995-08-09 2001-05-29 Rio Grande Medical Technologies, Inc. Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration
US6152876A (en) 1997-04-18 2000-11-28 Rio Grande Medical Technologies, Inc. Method for non-invasive blood analyte measurement with improved optical interface
US6212424B1 (en) 1998-10-29 2001-04-03 Rio Grande Medical Technologies, Inc. Apparatus and method for determination of the adequacy of dialysis by non-invasive near-infrared spectroscopy
EP0762109A3 (en) * 1995-08-30 1997-09-17 Kyoto Daiichi Kagaku Kk Method and device for measuring lactic acid in an organism
US5827181A (en) * 1995-09-07 1998-10-27 Hewlett-Packard Co. Noninvasive blood chemistry measurement method and system
US5760399A (en) * 1995-10-02 1998-06-02 Foss Nirsystems, Inc. Measurement of transmission spectra of pharmaceutical tablets
US6025597A (en) * 1995-10-17 2000-02-15 Optiscan Biomedical Corporation Non-invasive infrared absorption spectrometer for measuring glucose or other constituents in a human or other body
US6072180A (en) * 1995-10-17 2000-06-06 Optiscan Biomedical Corporation Non-invasive infrared absorption spectrometer for the generation and capture of thermal gradient spectra from living tissue
EP0862648B1 (en) * 1995-11-22 2004-10-06 Medtronic MiniMed, Inc. Detection of biological molecules using chemical amplification and optical sensors
US6002954A (en) * 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
US6405069B1 (en) 1996-01-31 2002-06-11 Board Of Regents, The University Of Texas System Time-resolved optoacoustic method and system for noninvasive monitoring of glucose
US6040578A (en) * 1996-02-02 2000-03-21 Instrumentation Metrics, Inc. Method and apparatus for multi-spectral analysis of organic blood analytes in noninvasive infrared spectroscopy
ATE209017T1 (de) 1996-02-05 2001-12-15 Diasense Inc Vorrichtung zur nicht-invasiven bestimmung von glukose
US6088605A (en) * 1996-02-23 2000-07-11 Diasense, Inc. Method and apparatus for non-invasive blood glucose sensing
JP3599878B2 (ja) * 1996-03-01 2004-12-08 テルモ株式会社 血糖計
US5666956A (en) * 1996-05-20 1997-09-16 Buchert; Janusz Michal Instrument and method for non-invasive monitoring of human tissue analyte by measuring the body's infrared radiation
DE19629342C2 (de) * 1996-07-20 1999-09-02 Epsa Elektronik Und Praezision Verfahren und Anordnung zur nicht-invasiven, transkutanen Bestimmung von Stoffkonzentrationen in Körpergeweben
WO1998022820A1 (en) 1996-11-21 1998-05-28 Lawrence Livermore National Laboratory Detection of biological molecules using boronate-based chemical amplification and optical sensors
JP4212007B2 (ja) * 1996-11-26 2009-01-21 パナソニック電工株式会社 血液成分濃度の分析装置
US5910109A (en) * 1997-02-20 1999-06-08 Emerging Technology Systems, Llc Non-invasive glucose measuring device and method for measuring blood glucose
WO1998037805A1 (en) 1997-02-26 1998-09-03 Diasense, Inc. Individual calibration of blood glucose for supporting noninvasive self-monitoring blood glucose
US6113541A (en) * 1997-03-07 2000-09-05 Agilent Technologies, Inc. Noninvasive blood chemistry measurement method and system
TW352335B (en) * 1997-03-25 1999-02-11 Matsushita Electric Works Ltd Method of determining a glucose concentration in a target by using near-infrared spectroscopy
US5961451A (en) * 1997-04-07 1999-10-05 Motorola, Inc. Noninvasive apparatus having a retaining member to retain a removable biosensor
US6560352B2 (en) 1999-10-08 2003-05-06 Lumidigm, Inc. Apparatus and method of biometric identification or verification of individuals using optical spectroscopy
US6628809B1 (en) 1999-10-08 2003-09-30 Lumidigm, Inc. Apparatus and method for identification of individuals by near-infrared spectrum
US7890158B2 (en) 2001-06-05 2011-02-15 Lumidigm, Inc. Apparatus and method of biometric determination using specialized optical spectroscopy systems
US6246893B1 (en) * 1997-06-12 2001-06-12 Tecmed Incorporated Method and device for glucose concentration measurement with special attention to blood glucose determinations
US7383069B2 (en) * 1997-08-14 2008-06-03 Sensys Medical, Inc. Method of sample control and calibration adjustment for use with a noninvasive analyzer
WO1999043255A1 (en) * 1998-02-25 1999-09-02 University Of Iowa Research Foundation Near infrared-transmission spectroscopy of tongue tissue
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6505059B1 (en) 1998-04-06 2003-01-07 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US7899518B2 (en) 1998-04-06 2011-03-01 Masimo Laboratories, Inc. Non-invasive tissue glucose level monitoring
US6728560B2 (en) 1998-04-06 2004-04-27 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US20020091324A1 (en) * 1998-04-06 2002-07-11 Nikiforos Kollias Non-invasive tissue glucose level monitoring
US6097975A (en) * 1998-05-13 2000-08-01 Biosensor, Inc. Apparatus and method for noninvasive glucose measurement
US6441388B1 (en) 1998-10-13 2002-08-27 Rio Grande Medical Technologies, Inc. Methods and apparatus for spectroscopic calibration model transfer
US6157041A (en) * 1998-10-13 2000-12-05 Rio Grande Medical Technologies, Inc. Methods and apparatus for tailoring spectroscopic calibration models
US7098037B2 (en) 1998-10-13 2006-08-29 Inlight Solutions, Inc. Accommodating subject and instrument variations in spectroscopic determinations
US7299080B2 (en) * 1999-10-08 2007-11-20 Sensys Medical, Inc. Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy
US6370407B1 (en) 1999-07-27 2002-04-09 Tecmed, Incorporated System for improving the sensitivity and stability of optical polarimetric measurements
WO2001016582A1 (en) * 1999-08-30 2001-03-08 Euro-Celtique S.A. In situ methods for measuring the release of a substance from a dosage form
US6673625B2 (en) 1999-09-15 2004-01-06 The Regents Of The University Of California Saccharide sensing molecules having enhanced fluorescent properties
US6682938B1 (en) 1999-09-15 2004-01-27 The Regents Of The University Of California Glucose sensing molecules having selected fluorescent properties
US6816605B2 (en) 1999-10-08 2004-11-09 Lumidigm, Inc. Methods and systems for biometric identification of individuals using linear optical spectroscopy
US7133710B2 (en) * 2002-03-08 2006-11-07 Sensys Medical, Inc. Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy
US6563585B1 (en) * 1999-11-24 2003-05-13 University Of Maryland Biotechnology Institute Ratiometric fluorometer
US7606608B2 (en) 2000-05-02 2009-10-20 Sensys Medical, Inc. Optical sampling interface system for in-vivo measurement of tissue
US20070179367A1 (en) * 2000-05-02 2007-08-02 Ruchti Timothy L Method and Apparatus for Noninvasively Estimating a Property of an Animal Body Analyte from Spectral Data
US7519406B2 (en) 2004-04-28 2009-04-14 Sensys Medical, Inc. Noninvasive analyzer sample probe interface method and apparatus
US6549861B1 (en) 2000-08-10 2003-04-15 Euro-Celtique, S.A. Automated system and method for spectroscopic analysis
WO2002016905A2 (en) 2000-08-21 2002-02-28 Euro-Celtique, S.A. Near infrared blood glucose monitoring system
AU2001291189A1 (en) 2000-09-22 2002-04-02 Knobbe, Lim And Buckingham Method and apparatus for real-time estimation and control of pysiological parameters
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
AU2002251944A1 (en) * 2001-02-15 2002-09-04 Medtronic Minimed, Inc. Polymers functionalized with fluorescent boronate motifs
US7126682B2 (en) 2001-04-11 2006-10-24 Rio Grande Medical Technologies, Inc. Encoded variable filter spectrometer
US7043288B2 (en) * 2002-04-04 2006-05-09 Inlight Solutions, Inc. Apparatus and method for spectroscopic analysis of tissue to detect diabetes in an individual
US6865408B1 (en) 2001-04-11 2005-03-08 Inlight Solutions, Inc. System for non-invasive measurement of glucose in humans
US6862091B2 (en) 2001-04-11 2005-03-01 Inlight Solutions, Inc. Illumination device and method for spectroscopic analysis
US6983176B2 (en) 2001-04-11 2006-01-03 Rio Grande Medical Technologies, Inc. Optically similar reference samples and related methods for multivariate calibration models used in optical spectroscopy
US6574490B2 (en) 2001-04-11 2003-06-03 Rio Grande Medical Technologies, Inc. System for non-invasive measurement of glucose in humans
AU2002315180A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Electric lancet actuator
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
DE60234598D1 (de) 2001-06-12 2010-01-14 Pelikan Technologies Inc Selbstoptimierende lanzettenvorrichtung mit adaptationsmittel für zeitliche schwankungen von hauteigenschaften
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US7045361B2 (en) 2001-09-12 2006-05-16 Medtronic Minimed, Inc. Analyte sensing via acridine-based boronate biosensors
US6731961B2 (en) 2001-11-09 2004-05-04 Optiscan Biomedical Corp. Method for transforming phase spectra to absorption spectra
WO2003045235A1 (en) * 2001-11-21 2003-06-05 Optiscan Biomedical Corporation Method for adjusting a blood analyte measurement
US20030175806A1 (en) * 2001-11-21 2003-09-18 Peter Rule Method and apparatus for improving the accuracy of alternative site analyte concentration measurements
US8718738B2 (en) 2002-03-08 2014-05-06 Glt Acquisition Corp. Method and apparatus for coupling a sample probe with a sample site
US7697966B2 (en) 2002-03-08 2010-04-13 Sensys Medical, Inc. Noninvasive targeting system method and apparatus
US8504128B2 (en) 2002-03-08 2013-08-06 Glt Acquisition Corp. Method and apparatus for coupling a channeled sample probe to tissue
US6654125B2 (en) 2002-04-04 2003-11-25 Inlight Solutions, Inc Method and apparatus for optical spectroscopy incorporating a vertical cavity surface emitting laser (VCSEL) as an interferometer reference
US7027848B2 (en) * 2002-04-04 2006-04-11 Inlight Solutions, Inc. Apparatus and method for non-invasive spectroscopic measurement of analytes in tissue using a matched reference analyte
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7620212B1 (en) 2002-08-13 2009-11-17 Lumidigm, Inc. Electro-optical sensor
EP1536730A2 (en) * 2002-09-10 2005-06-08 Euro-Celtique, S.A. Apparatus and method for non-invasive measurement of blood constituents
CN100483106C (zh) * 2002-09-29 2009-04-29 天津市先石光学技术有限公司 可分离介质表层与深层信息的光学检测方法
US7174198B2 (en) * 2002-12-27 2007-02-06 Igor Trofimov Non-invasive detection of analytes in a complex matrix
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
WO2004060154A1 (en) * 2003-01-07 2004-07-22 Intelligent Photonics Control Corp. Non-invasive blood monitor
US7347365B2 (en) 2003-04-04 2008-03-25 Lumidigm, Inc. Combined total-internal-reflectance and tissue imaging systems and methods
US7545963B2 (en) 2003-04-04 2009-06-09 Lumidigm, Inc. Texture-biometrics sensor
US7627151B2 (en) 2003-04-04 2009-12-01 Lumidigm, Inc. Systems and methods for improved biometric feature definition
US7460696B2 (en) 2004-06-01 2008-12-02 Lumidigm, Inc. Multispectral imaging biometrics
US7394919B2 (en) 2004-06-01 2008-07-01 Lumidigm, Inc. Multispectral biometric imaging
US7539330B2 (en) 2004-06-01 2009-05-26 Lumidigm, Inc. Multispectral liveness determination
US7751594B2 (en) 2003-04-04 2010-07-06 Lumidigm, Inc. White-light spectral biometric sensors
US7668350B2 (en) 2003-04-04 2010-02-23 Lumidigm, Inc. Comparative texture analysis of tissue for biometric spoof detection
JP2007524441A (ja) 2003-04-04 2007-08-30 ルミディム インコーポレイテッド マルチスペクトルバイオメトリックセンサ
US7633621B2 (en) * 2003-04-11 2009-12-15 Thornton Robert L Method for measurement of analyte concentrations and semiconductor laser-pumped, small-cavity fiber lasers for such measurements and other applications
US7283242B2 (en) * 2003-04-11 2007-10-16 Thornton Robert L Optical spectroscopy apparatus and method for measurement of analyte concentrations or other such species in a specimen employing a semiconductor laser-pumped, small-cavity fiber laser
US7271912B2 (en) 2003-04-15 2007-09-18 Optiscan Biomedical Corporation Method of determining analyte concentration in a sample using infrared transmission data
US6975892B2 (en) 2003-10-21 2005-12-13 Oculir, Inc. Methods for non-invasive analyte measurement from the conjunctiva
US6968222B2 (en) 2003-05-02 2005-11-22 Oculir, Inc. Methods and device for non-invasive analyte measurement
US6958039B2 (en) 2003-05-02 2005-10-25 Oculir, Inc. Method and instruments for non-invasive analyte measurement
EP2238892A3 (en) 2003-05-30 2011-02-09 Pelikan Technologies Inc. Apparatus for body fluid sampling
WO2004107964A2 (en) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Blood harvesting device with electronic control
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
WO2005007215A2 (en) * 2003-07-09 2005-01-27 Glucolight Corporation Method and apparatus for tissue oximetry
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
EP1680014A4 (en) 2003-10-14 2009-01-21 Pelikan Technologies Inc METHOD AND APPARATUS PROVIDING A VARIABLE USER INTERFACE
US20060224057A1 (en) * 2003-10-21 2006-10-05 Oculir, Inc. Methods for non-invasive analyte measurement
US7570357B2 (en) * 2003-11-10 2009-08-04 Kyokko Denki Kabushiki Kaisha Visible/near-infrared spectrometry and its device
US7263213B2 (en) 2003-12-11 2007-08-28 Lumidigm, Inc. Methods and systems for estimation of personal characteristics from biometric measurements
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US7510849B2 (en) * 2004-01-29 2009-03-31 Glucolight Corporation OCT based method for diagnosis and therapy
JP2007527750A (ja) * 2004-03-06 2007-10-04 カリスト メディカル,インク. 生体内物質の量的情報を非侵襲的に測定する方法及びデバイス
US8868147B2 (en) 2004-04-28 2014-10-21 Glt Acquisition Corp. Method and apparatus for controlling positioning of a noninvasive analyzer sample probe
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
US7508965B2 (en) 2004-06-01 2009-03-24 Lumidigm, Inc. System and method for robust fingerprint acquisition
US20110163163A1 (en) * 2004-06-01 2011-07-07 Lumidigm, Inc. Multispectral barcode imaging
US8229185B2 (en) 2004-06-01 2012-07-24 Lumidigm, Inc. Hygienic biometric sensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc METHOD AND APPARATUS FOR MANUFACTURING A DEVICE FOR SAMPLING LIQUIDS
US8036727B2 (en) 2004-08-11 2011-10-11 Glt Acquisition Corp. Methods for noninvasively measuring analyte levels in a subject
US7822452B2 (en) 2004-08-11 2010-10-26 Glt Acquisition Corp. Method for data reduction and calibration of an OCT-based blood glucose monitor
US8787630B2 (en) 2004-08-11 2014-07-22 Lumidigm, Inc. Multispectral barcode imaging
US7254429B2 (en) * 2004-08-11 2007-08-07 Glucolight Corporation Method and apparatus for monitoring glucose levels in a biological tissue
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
EP1841355A4 (en) * 2005-01-12 2012-09-05 King Pharmaceuticals Res & Dev METHOD FOR DETECTING MYOCARDIAL DYSFUNCTION IN PATIENTS SUFFERING IN THE ASTHMA OR BRONCHOSPASM PASS
US7801338B2 (en) 2005-04-27 2010-09-21 Lumidigm, Inc. Multispectral biometric sensors
US8140139B2 (en) 2005-06-14 2012-03-20 Dominion Assets, Llc Method and apparatus for the non-invasive sensing of glucose in a human subject
US8292920B2 (en) 2005-11-10 2012-10-23 Tyco Healthcare Group Lp Sickle needle and method
US8175346B2 (en) 2006-07-19 2012-05-08 Lumidigm, Inc. Whole-hand multispectral biometric imaging
US8355545B2 (en) 2007-04-10 2013-01-15 Lumidigm, Inc. Biometric detection using spatial, temporal, and/or spectral techniques
US7995808B2 (en) 2006-07-19 2011-08-09 Lumidigm, Inc. Contactless multispectral biometric capture
EP2041696B1 (en) 2006-07-19 2020-11-18 HID Global Corporation Multibiometric multispectral imager
US7804984B2 (en) 2006-07-31 2010-09-28 Lumidigm, Inc. Spatial-spectral fingerprint spoof detection
US7801339B2 (en) 2006-07-31 2010-09-21 Lumidigm, Inc. Biometrics with spatiospectral spoof detection
US8180419B2 (en) * 2006-09-27 2012-05-15 Nellcor Puritan Bennett Llc Tissue hydration estimation by spectral absorption bandwidth measurement
US8285010B2 (en) 2007-03-21 2012-10-09 Lumidigm, Inc. Biometrics based on locally consistent features
US9080942B2 (en) 2007-04-18 2015-07-14 The Research Foundation for State University of New York Flexible multi-moduled nanoparticle-structured sensor array on polymer substrate and methods for manufacture
US7734321B2 (en) * 2007-07-13 2010-06-08 All Protect, Llc Apparatus for non-invasive spectroscopic measurement of analytes, and method of using the same
WO2009111542A2 (en) 2008-03-04 2009-09-11 Glucolight Corporation Methods and systems for analyte level estimation in optical coherence tomography
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
CN101292875B (zh) * 2008-06-06 2010-07-14 天津市先石光学技术有限公司 利用基准波长测量成分浓度的方法
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US10475529B2 (en) 2011-07-19 2019-11-12 Optiscan Biomedical Corporation Method and apparatus for analyte measurements using calibration sets
DE112010003414T5 (de) 2009-08-26 2012-12-06 Lumidigm, Inc. Biometrische Multiplex-Bildgebung und biometrischer Dual-Bilderzeugersensor
US8570149B2 (en) 2010-03-16 2013-10-29 Lumidigm, Inc. Biometric imaging using an optical adaptive interface
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8235897B2 (en) 2010-04-27 2012-08-07 A.D. Integrity Applications Ltd. Device for non-invasively measuring glucose
KR20130129168A (ko) 2010-06-22 2013-11-27 센스펙 게엠베하 측정 매체의 성분 또는 특성, 특히 물리적 혈액 값의 확인 및 모니터링 장치 및 방법
US8843186B2 (en) 2012-11-21 2014-09-23 Folim G. Halaka Non-invasive reagentless glucose determination
US9693694B2 (en) 2012-11-21 2017-07-04 Folim G. Halaka Cancer cell detection using dielectrophoretic dynamic light scattering (DDLS) spectroscopy
US9977947B2 (en) * 2015-08-25 2018-05-22 Gingy Technology Inc. Fingerprint identification method and device thereof
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
US10512425B2 (en) 2016-08-04 2019-12-24 United States Of America As Represented By The Secretary Of The Navy Dermatologically non-abrasive blood testing using an interferometry optical design
CN108051423A (zh) * 2017-11-24 2018-05-18 武汉比色光电科技有限公司 一种血液光学检测方法和装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE42673T1 (de) * 1984-05-04 1989-05-15 Kurashiki Boseki Kk Spektrophotometrisches geraet zur unblutigen bestimmung von glukose in lebendem gewebe.
US4791296A (en) * 1987-08-04 1988-12-13 Inmos Corporation Fast method of measuring phosphorous concentration in PSG and BPSG films
US5028787A (en) * 1989-01-19 1991-07-02 Futrex, Inc. Non-invasive measurement of blood glucose
US4975581A (en) * 1989-06-21 1990-12-04 University Of New Mexico Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids
US5070874A (en) * 1990-01-30 1991-12-10 Biocontrol Technology, Inc. Non-invasive determination of glucose concentration in body of patients
WO1991011136A1 (en) * 1990-02-02 1991-08-08 Boston Advanced Technologies, Inc. Systems for material analysis based on reflectance ratio detection

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020152380A1 (es) 2019-01-22 2020-07-30 Universidad De Sevilla Dispositivo portable y método para la estimación no invasiva del nivel de glucosa en sangre

Also Published As

Publication number Publication date
US5070874A (en) 1991-12-10
ATE152338T1 (de) 1997-05-15
DE69125942D1 (de) 1997-06-05
CA2056868C (en) 1996-03-26
EP0548418A1 (en) 1993-06-30
DK0548418T3 (da) 1997-07-28
AU8839291A (en) 1993-06-10
EP0548418B1 (en) 1997-05-02
DE69125942T2 (de) 1997-10-30
AU643855B2 (en) 1993-11-25
CA2056868A1 (en) 1993-06-04

Similar Documents

Publication Publication Date Title
ES2101728T3 (es) Determinacion no invasiva de la concentracion de glucosa en el cuerpo de un paciente.
WO1995006431A3 (en) A robust accurate non-invasive analyte monitor
TW350396U (en) Hair cutting apparatus
EA199900145A1 (ru) Неинвазивный непрерывный контроль за уровнем глюкозы в крови
EP0843986A3 (en) Device for non-invasive determination of glucose concentration in blood
ES2187870T3 (es) Aparato para terapia con un dispositivo de irradiacion por laser.
SE8503687L (sv) For oforstorande undersokning avsedd fotometer for multipelvaglengdspulsat ljus
AU5842596A (en) Method and apparatus for rapid non-invasive determination of blood composition parameters
EP1231496A3 (en) Optical coherence tomography assisted surgical apparatus
ES2101092T3 (es) Procedimiento y aparato para controlar la concentracion de glucosa.
WO2003003903A3 (en) Laser device for medical/cosmetic procedures
EP0317121A3 (en) Spectroscopic method and apparatus for measuring sugar concentrations
EP0728440A3 (de) Auswerteverfahren und Vorrichtung zur tiefenselektiven, nicht-invasiven Detektion von Muskelaktivitäten
ATE137942T1 (de) Rückgratretraktor
EP0003015A1 (en) Apparatus for non-invasive detection of zinc protoporphyrin in erythrocytes
CA2323434A1 (en) Spectroreflectometric measurement of oxygenation in a patient's eye
DE3776042D1 (de) Vorrichtung zur beobachtung und laserbehandlung des auges.
EP1075063A3 (en) Method and device for stabilizing the emission wavelength of a laser
NO990658L (no) Anordning for sikker, smertefri og varig fjerning av u°nsket hÕrvekst
Cs Microprocessor-based system for measurement of the characteristics of ultra-short laser pulses
LP An X-ray microdensitometer
FI892973A (fi) Givare foer oximeter.
JPS57132651A (en) Image pickup tube

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 548418

Country of ref document: ES