EA199900145A1 - Неинвазивный непрерывный контроль за уровнем глюкозы в крови - Google Patents

Неинвазивный непрерывный контроль за уровнем глюкозы в крови

Info

Publication number
EA199900145A1
EA199900145A1 EA199900145A EA199900145A EA199900145A1 EA 199900145 A1 EA199900145 A1 EA 199900145A1 EA 199900145 A EA199900145 A EA 199900145A EA 199900145 A EA199900145 A EA 199900145A EA 199900145 A1 EA199900145 A1 EA 199900145A1
Authority
EA
Eurasian Patent Office
Prior art keywords
blood
analyte
concentration
human
glucose
Prior art date
Application number
EA199900145A
Other languages
English (en)
Other versions
EA002288B1 (ru
Inventor
Януш М. Бухерт
Original Assignee
Януш М. Бухерт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Януш М. Бухерт filed Critical Януш М. Бухерт
Publication of EA199900145A1 publication Critical patent/EA199900145A1/ru
Publication of EA002288B1 publication Critical patent/EA002288B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A61B5/6815—Ear
    • A61B5/6817—Ear canal
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J5/00—Radiation pyrometry, e.g. infrared or optical thermometry
    • G01J5/02—Constructional details
    • G01J5/08—Optical arrangements
    • G01J5/0801—Means for wavelength selection or discrimination
    • G01J5/0802—Optical filters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J5/00—Radiation pyrometry, e.g. infrared or optical thermometry
    • G01J5/10—Radiation pyrometry, e.g. infrared or optical thermometry using electric radiation detectors
    • G01J5/12—Radiation pyrometry, e.g. infrared or optical thermometry using electric radiation detectors using thermoelectric elements, e.g. thermocouples
    • G01J5/14—Electrical features thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Раскрыт способ и устройство для непрерывного неинвазивного выявления концентрации анализируемого вещества (например, глюкозы) в ткани организма человека, такой как кровь. Комплект дистанционного датчика (7) устройства, установленный в наружном слуховом проходе человека, непрерывно измеряет концентрацию анализируемого вещества с помощью выявления инфракрасного излучения, естественно испускаемого телом человека. В нем используется детектор инфракрасного излучения (7) с комбинацией соответствующих фильтров (6) таких, например, как фильтр отрицательной корреляции или узкополосные фильтры или другие комплекты детекторных фильтров. Способ и устройство основаны на открытии, что естественное испускание инфракрасного излучения телом человека, особенно барабанной перепонкой (1), модулируется состоянием испускающей ткани. Спектральная излучательная способность инфракрасного излучения барабанной перепонки (1) человека состоит из спектральной информации о наличии анализируемого вещества (например, глюкозы) в ткани (например, крови). Это может находиться в прямой корреляции с концентрацией анализируемого вещества в крови, например с концентрацией глюкозы в крови.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900145A 1997-05-20 1998-05-18 Неинвазивный непрерывный контроль за уровнем глюкозы в крови EA002288B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/859,579 US5823966A (en) 1997-05-20 1997-05-20 Non-invasive continuous blood glucose monitoring
PCT/US1998/010012 WO1998052469A1 (en) 1997-05-20 1998-05-18 Non-invasive continuous blood glucose monitoring

Publications (2)

Publication Number Publication Date
EA199900145A1 true EA199900145A1 (ru) 1999-08-26
EA002288B1 EA002288B1 (ru) 2002-02-28

Family

ID=25331255

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900145A EA002288B1 (ru) 1997-05-20 1998-05-18 Неинвазивный непрерывный контроль за уровнем глюкозы в крови

Country Status (10)

Country Link
US (1) US5823966A (ru)
EP (1) EP0939603A4 (ru)
JP (1) JP2001506164A (ru)
KR (1) KR100695761B1 (ru)
AU (1) AU7491798A (ru)
CA (1) CA2290957C (ru)
EA (1) EA002288B1 (ru)
IL (1) IL128106A (ru)
PL (1) PL331145A1 (ru)
WO (1) WO1998052469A1 (ru)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002953A (en) * 1998-05-06 1999-12-14 Optix Lp Non-invasive IR transmission measurement of analyte in the tympanic membrane
US6080110A (en) * 1999-04-19 2000-06-27 Tel, Inc. Heartbeat monitor for wearing during exercise
US6442411B1 (en) 1999-04-21 2002-08-27 Optix, Lp Method for improving calibration of an instrument for non-invasively measuring constituents in arterial blood
DE19952215C2 (de) * 1999-10-29 2001-10-31 Roche Diagnostics Gmbh Testelement-Analysesystem
DE10020615C2 (de) * 2000-04-27 2002-02-28 Glukomeditech Ag Verfahren zur langzeitstabilen und gut reproduzierbaren spektrometrischen Messung der Konzentrationen der Bestandteile wässriger Lösungen sowie Vorrichtung zur Durchführung dieses Verfahrens
US6549861B1 (en) 2000-08-10 2003-04-15 Euro-Celtique, S.A. Automated system and method for spectroscopic analysis
WO2002016905A2 (en) 2000-08-21 2002-02-28 Euro-Celtique, S.A. Near infrared blood glucose monitoring system
US6549796B2 (en) * 2001-05-25 2003-04-15 Lifescan, Inc. Monitoring analyte concentration using minimally invasive devices
US20030171655A1 (en) * 2002-03-08 2003-09-11 Newman Richard W. Combination otoscope
US20040132171A1 (en) * 2003-01-06 2004-07-08 Peter Rule Wearable device for measuring analyte concentration
US7406185B2 (en) * 2003-04-16 2008-07-29 Ligh Tuning Technology Inc. Thermoelectric sensor for fingerprint thermal imaging
US6975892B2 (en) 2003-10-21 2005-12-13 Oculir, Inc. Methods for non-invasive analyte measurement from the conjunctiva
US6958039B2 (en) * 2003-05-02 2005-10-25 Oculir, Inc. Method and instruments for non-invasive analyte measurement
US6968222B2 (en) * 2003-05-02 2005-11-22 Oculir, Inc. Methods and device for non-invasive analyte measurement
US20050043630A1 (en) * 2003-08-21 2005-02-24 Buchert Janusz Michal Thermal Emission Non-Invasive Analyte Monitor
CA2556592C (en) 2004-02-26 2014-01-28 Lars Gustaf Liljeryd Metabolic monitoring, a method and apparatus for indicating a health-related condition of a subject
US20060258919A1 (en) * 2004-04-14 2006-11-16 Oculir, Inc. Non-Invasive Analyte Measurement Device for Measuring Tears and Other Ocular Elements Using Electromagnetic Radiation and Method of Using the Same
US20080009688A1 (en) * 2004-04-14 2008-01-10 Oculir, Inc. Methods for non-invasive analyte measurement
ITMI20041644A1 (it) * 2004-08-11 2004-11-11 Eni Spa Procedimento per lo stoccaggio di zolfo ad emissione zero
CN101188968B (zh) * 2005-03-09 2010-09-29 拉米尔·法里托维奇·穆辛 微量热学测定组织局部代谢率、细胞间质水含量、血液生化成分的浓度和心血管系统张力的方法和装置
WO2006112837A1 (en) * 2005-04-17 2006-10-26 Janusz Michal Buchert Thermal emission non-invasive analyte monitor
JPWO2006132218A1 (ja) * 2005-06-07 2009-01-08 オムロンヘルスケア株式会社 生体成分計測センサ
CN101184438A (zh) * 2005-06-07 2008-05-21 欧姆龙健康医疗事业株式会社 生物体信息计测传感器
CN101184440A (zh) * 2005-06-07 2008-05-21 欧姆龙健康医疗事业株式会社 生物体信息计测传感器
WO2007007459A1 (ja) * 2005-07-12 2007-01-18 Omron Healthcare Co., Ltd. 生体の成分に関する情報を正確に測定できる生化学計測器
EP1955652A1 (en) * 2005-10-21 2008-08-13 Matsushita Electric Industrial Co., Ltd. Biometric information measuring device
WO2007049562A1 (ja) * 2005-10-24 2007-05-03 Matsushita Electric Industrial Co., Ltd. 生体成分濃度測定装置
JP4071822B2 (ja) * 2006-03-10 2008-04-02 松下電器産業株式会社 生体成分濃度測定装置
CN101400301A (zh) * 2006-03-10 2009-04-01 松下电器产业株式会社 生物体成分浓度测定装置
US8326390B2 (en) * 2006-07-25 2012-12-04 Edward Belotserkovsky Optical non-invasive blood monitoring system and method
US7486976B1 (en) 2006-07-25 2009-02-03 Edward Belotserkovsky Optical non-invasive blood monitoring system and method
US8401604B2 (en) * 2008-04-11 2013-03-19 Glucovista, Llc Apparatus and methods for non-invasive measurement of a substance within a body
WO2010033104A1 (en) * 2008-09-20 2010-03-25 Edward Belotserkovsky Optical non-invasive blood monitoring system and method
US20110082711A1 (en) 2009-10-06 2011-04-07 Masimo Laboratories, Inc. Personal digital assistant or organizer for monitoring glucose levels
US10067054B2 (en) 2012-10-16 2018-09-04 K Sciences Gp, Llc Simple sugar concentration sensor and method
US8843186B2 (en) 2012-11-21 2014-09-23 Folim G. Halaka Non-invasive reagentless glucose determination
US9693694B2 (en) 2012-11-21 2017-07-04 Folim G. Halaka Cancer cell detection using dielectrophoretic dynamic light scattering (DDLS) spectroscopy
US10772541B2 (en) 2014-08-21 2020-09-15 I. R. Med Ltd. System and method for noninvasive analysis of subcutaneous tissue
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
RU2607494C1 (ru) * 2015-07-15 2017-01-10 Федеральное государственное бюджетное образовательное учреждение высшего образования "Тамбовский государственный технический университет"(ФГБОУ ВО "ТГТУ") Неинвазивный способ определения концентрации глюкозы в крови
US10973470B2 (en) 2015-07-19 2021-04-13 Sanmina Corporation System and method for screening and prediction of severity of infection
US10888280B2 (en) 2016-09-24 2021-01-12 Sanmina Corporation System and method for obtaining health data using a neural network
US10744261B2 (en) 2015-09-25 2020-08-18 Sanmina Corporation System and method of a biosensor for detection of vasodilation
US10194871B2 (en) 2015-09-25 2019-02-05 Sanmina Corporation Vehicular health monitoring system and method
US10932727B2 (en) 2015-09-25 2021-03-02 Sanmina Corporation System and method for health monitoring including a user device and biosensor
US10321860B2 (en) 2015-07-19 2019-06-18 Sanmina Corporation System and method for glucose monitoring
US10952682B2 (en) 2015-07-19 2021-03-23 Sanmina Corporation System and method of a biosensor for detection of health parameters
US10750981B2 (en) 2015-09-25 2020-08-25 Sanmina Corporation System and method for health monitoring including a remote device
US10736580B2 (en) 2016-09-24 2020-08-11 Sanmina Corporation System and method of a biosensor for detection of microvascular responses
US9636457B2 (en) 2015-07-19 2017-05-02 Sanmina Corporation System and method for a drug delivery and biosensor patch
US9788767B1 (en) 2015-09-25 2017-10-17 Sanmina Corporation System and method for monitoring nitric oxide levels using a non-invasive, multi-band biosensor
US10874333B2 (en) 2015-09-15 2020-12-29 Massachusetts Institute Of Technology Systems and methods for diagnosis of middle ear conditions and detection of analytes in the tympanic membrane
US10945676B2 (en) 2015-09-25 2021-03-16 Sanmina Corporation System and method for blood typing using PPG technology
US11426100B1 (en) * 2015-12-08 2022-08-30 Socrates Health Solutions, Inc. Blood glucose trend meter
CN108601529B (zh) 2015-12-31 2022-02-25 威尔图比有限公司 用于生理测量的无创监测的设备、系统和方法
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
RU2629796C1 (ru) 2016-05-23 2017-09-04 Общество с ограниченной ответственностью "Лаборатория межклеточных технологий "Интерсел Рэнд" (ООО "Интерсел Рэнд") Способ и мультисенсорное устройство для неинвазивного мониторинга уровня глюкозы в крови
TWI597690B (zh) * 2016-09-23 2017-09-01 財團法人國家實驗硏究院 影像式血糖濃度檢測裝置及其方法
EP3443887A1 (de) * 2017-08-18 2019-02-20 Swiss Spectral AG Vorrichtung und verfahren zur nicht-invasiven bestimmung von analyten ohne externe strahlungsquelle
CA3075474C (en) * 2017-09-11 2023-12-19 Muralidharan GOPALAKRISHNAN Non-invasive multifunctional telemetry apparatus and real-time system for monitoring clinical signals and health parameters
CN108261286B (zh) * 2017-11-29 2021-10-12 北京华夏光谷光电科技有限公司 一种无损血糖检测与激光针刺耳穴的复用耳罩
US10466783B2 (en) 2018-03-15 2019-11-05 Sanmina Corporation System and method for motion detection using a PPG sensor
EP4216570A1 (en) * 2018-09-19 2023-07-26 Sonion Nederland B.V. A housing comprising a sensor
RU2752711C2 (ru) 2019-11-18 2021-07-30 Общество с ограниченной ответственностью «Лаборатория межклеточных технологий «Интерсел Рэнд» (ООО «Интерсел Рэнд») Способ и устройство для спектроскопии живой ткани

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3958560A (en) * 1974-11-25 1976-05-25 Wayne Front March Non-invasive automatic glucose sensor system
US4790324A (en) * 1984-10-23 1988-12-13 Intelligent Medical Systems, Inc. Method and apparatus for measuring internal body temperature utilizing infrared emissions
EP0786649B1 (en) * 1985-04-17 2002-07-03 Thermoscan Inc. Infrared electronic thermometer and method for measuring temperature
US4890621A (en) * 1988-01-19 1990-01-02 Northstar Research Institute, Ltd. Continuous glucose monitoring and a system utilized therefor
US4882492A (en) * 1988-01-19 1989-11-21 Biotronics Associates, Inc. Non-invasive near infrared measurement of blood analyte concentrations
JP2826337B2 (ja) * 1988-04-12 1998-11-18 シチズン時計株式会社 放射体温計
US5402778A (en) * 1993-01-19 1995-04-04 Nim Incorporated Spectrophotometric examination of tissue of small dimension
US5086229A (en) * 1989-01-19 1992-02-04 Futrex, Inc. Non-invasive measurement of blood glucose
US5115133A (en) * 1990-04-19 1992-05-19 Inomet, Inc. Testing of body fluid constituents through measuring light reflected from tympanic membrane
US5079421A (en) * 1990-04-19 1992-01-07 Inomet, Inc. Invasive FTIR blood constituent testing
US5313951A (en) * 1990-07-19 1994-05-24 Shi Zhao Device and a method to measure the infrared radiation of the human body
US5159936A (en) * 1990-08-17 1992-11-03 Mark Yelderman Noncontact infrared tympanic thermometer
US5469855A (en) * 1991-03-08 1995-11-28 Exergen Corporation Continuous temperature monitor
US5127742A (en) * 1991-04-19 1992-07-07 Thermoscan Inc. Apparatus and method for temperature measurement by radiation
US5178464A (en) * 1991-04-19 1993-01-12 Thermoscan Inc. Balance infrared thermometer and method for measuring temperature
US5452716A (en) * 1992-02-25 1995-09-26 Novo Nordisk A/S Method and device for in vivo measuring the concentration of a substance in the blood
US5370114A (en) * 1992-03-12 1994-12-06 Wong; Jacob Y. Non-invasive blood chemistry measurement by stimulated infrared relaxation emission
US5615672A (en) * 1993-01-28 1997-04-01 Optiscan, Inc. Self-emission noninvasive infrared spectrophotometer with body temperature compensation
US5515847A (en) * 1993-01-28 1996-05-14 Optiscan, Inc. Self-emission noninvasive infrared spectrophotometer
US5313941A (en) * 1993-01-28 1994-05-24 Braig James R Noninvasive pulsed infrared spectrophotometer
US5368038A (en) * 1993-03-08 1994-11-29 Thermoscan Inc. Optical system for an infrared thermometer
US5460177A (en) * 1993-05-07 1995-10-24 Diasense, Inc. Method for non-invasive measurement of concentration of analytes in blood using continuous spectrum radiation
US5383452A (en) * 1993-07-01 1995-01-24 Buchert; Janusz Method, apparatus and procedure for non-invasive monitoring blood glucose by measuring the polarization ratio of blood luminescence
US5626139A (en) * 1994-09-23 1997-05-06 Artech Industries, Inc. Tympanic thermometer
US5666956A (en) * 1996-05-20 1997-09-16 Buchert; Janusz Michal Instrument and method for non-invasive monitoring of human tissue analyte by measuring the body's infrared radiation

Also Published As

Publication number Publication date
CA2290957C (en) 2004-12-14
IL128106A0 (en) 1999-11-30
AU7491798A (en) 1998-12-11
EA002288B1 (ru) 2002-02-28
EP0939603A4 (en) 2005-12-14
US5823966A (en) 1998-10-20
JP2001506164A (ja) 2001-05-15
IL128106A (en) 2004-08-31
WO1998052469A1 (en) 1998-11-26
KR20000029457A (ko) 2000-05-25
EP0939603A1 (en) 1999-09-08
CA2290957A1 (en) 1998-11-26
KR100695761B1 (ko) 2007-03-16
PL331145A1 (en) 1999-06-21

Similar Documents

Publication Publication Date Title
EA199900145A1 (ru) Неинвазивный непрерывный контроль за уровнем глюкозы в крови
US4380240A (en) Apparatus for monitoring metabolism in body organs
US5179951A (en) Blood constituent measurement
AU2599697A (en) Instrument and method for non-invasive monitoring of human tissue analyte by measuring the body's infrared radiation
TW336891B (en) Device for non-invasive determination of a glucose concentration in the blood of a subject
US5343818A (en) Photoplethysmographics using energy-reducing waveform shaping
CA2221864A1 (en) Active pulse blood constituent monitoring
AU2002358128A1 (en) Method and device for monitoring analyte concentration by optical detection
AU4694499A (en) Trace level detection of analytes using artificial olfactometry
CA2215163A1 (en) Isolated layer pulse oximetry
DE59914832D1 (de) Vorrichtung zur nichtinvasiven bestimmung des sauerstoffumsatzes in geweben
ES2101728T3 (es) Determinacion no invasiva de la concentracion de glucosa en el cuerpo de un paciente.
US20050049468A1 (en) Increasing the performance of an optical pulsoximeter
AU4634799A (en) Non-invasive measurement of blood analytes
DE69635075D1 (de) System zur überwachung des blutglucosespiegels
AU2002226251A1 (en) Breast cap
WO2007112431B1 (en) Synchronization of illumination source and sensor for improved visualization of subcutaneous structures
IL155349A0 (en) Analyte concentration determination devices and methods of using the same
ES2822555T3 (es) Dispositivo para la medición no invasiva de la glucemia
SE8503687L (sv) For oforstorande undersokning avsedd fotometer for multipelvaglengdspulsat ljus
CA2465889A1 (en) Reagent-less whole-blood glucose meter
DE59510901D1 (de) Photoakustischer Gassensor und dessen Verwendung
EP1491135A3 (en) Method and apparatus for monitoring blood constituents
US20070270702A1 (en) Portable electronic device
WO2005063117A3 (en) Glucometer comprising an implantable light source

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ