ES2099577T3 - Nuevas triazolopirimidonas, su obtencion y su empleo. - Google Patents

Nuevas triazolopirimidonas, su obtencion y su empleo.

Info

Publication number
ES2099577T3
ES2099577T3 ES94901898T ES94901898T ES2099577T3 ES 2099577 T3 ES2099577 T3 ES 2099577T3 ES 94901898 T ES94901898 T ES 94901898T ES 94901898 T ES94901898 T ES 94901898T ES 2099577 T3 ES2099577 T3 ES 2099577T3
Authority
ES
Spain
Prior art keywords
triazolopirimidonas
employment
obtaining
new
triazolopyrimidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94901898T
Other languages
English (en)
Inventor
Rainer Schlecker
Hans-Joerg Treiber
Berthold Behl
Hans Peter Hofmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2099577T3 publication Critical patent/ES2099577T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN TRIAZOLOPIRIMIDONAS DE LA FORMULA (I), DONDE A, B,Y X POSEEN EL SIGNIFICADO DADO EN LA DESCRIPCION, ASI COMO SU ELABORACION. LOS NUEVOS COMPUESTOS SON APROPIADOS PARA TRATAMIENTO DE ENFERMEDADES DEL SISTEMA NERVIOSO CENTRAL. ENTRE ELLAS SE ENCUENTRAN ENFERMEDADES ESPECIALES, COMO LAS ORIGINADAS MEDIANTE DESORDENES AGUDOS O CRONICOS DE LA CIRCULACION Y/O METABOLISMO CELULAR, TALES COMO ALTERACIONES CEREBRALES ISQUEMICAS, ENCEFALOPATIA VASCULAR Y ENFERMEDADES DEMENCIALES RESULTANTES, EPILEPSIA, ENFERMEDAD DE PARKINSON, DEPRESION, MIGRAÑA, ASI COMO LESIONES TRAUMATICAS DEL CEREBRO Y DE LA ESPINA DORSAL.
ES94901898T 1992-12-10 1993-11-27 Nuevas triazolopirimidonas, su obtencion y su empleo. Expired - Lifetime ES2099577T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4241562A DE4241562A1 (de) 1992-12-10 1992-12-10 Neue Triazolopyrimidone, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ES2099577T3 true ES2099577T3 (es) 1997-05-16

Family

ID=6474848

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94901898T Expired - Lifetime ES2099577T3 (es) 1992-12-10 1993-11-27 Nuevas triazolopirimidonas, su obtencion y su empleo.

Country Status (22)

Country Link
US (1) US5654310A (es)
EP (1) EP0673378B1 (es)
JP (1) JP3490445B2 (es)
CN (1) CN1098414A (es)
AT (1) ATE150023T1 (es)
AU (1) AU674371B2 (es)
CA (1) CA2151243A1 (es)
CZ (1) CZ144995A3 (es)
DE (2) DE4241562A1 (es)
DK (1) DK0673378T3 (es)
ES (1) ES2099577T3 (es)
FI (1) FI952856A0 (es)
GR (1) GR3022980T3 (es)
HU (1) HUT72300A (es)
IL (1) IL107916A (es)
MX (1) MX9307735A (es)
NO (1) NO952291L (es)
NZ (1) NZ258558A (es)
PL (1) PL309329A1 (es)
RU (1) RU95121818A (es)
WO (1) WO1994013673A1 (es)
ZA (1) ZA939228B (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053600A (en) * 1973-03-08 1977-10-11 Sandoz, Inc. Tricyclic 1,2,4-triazolo-quinazolines
US4128644A (en) * 1977-07-29 1978-12-05 E. R. Squibb & Sons, Inc. Pyrazolo(1,5-c)quinazoline derivatives and related compounds
DE3146599A1 (de) * 1981-11-25 1983-07-07 Basf Ag, 6700 Ludwigshafen Neue triazolochinazoline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
EP0217748B1 (en) * 1985-09-30 1991-02-06 Ciba-Geigy Ag 2-Substituted-e-fused-[1,2,4,]triazolo-[1,5-c]pyrimidines pharmaceutical compositions and uses thereof
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof

Also Published As

Publication number Publication date
JPH08504412A (ja) 1996-05-14
HUT72300A (en) 1996-04-29
IL107916A (en) 1996-09-12
MX9307735A (es) 1994-06-30
FI952856A (fi) 1995-06-09
DK0673378T3 (da) 1997-07-21
WO1994013673A1 (de) 1994-06-23
CZ144995A3 (en) 1995-12-13
HU9501692D0 (en) 1995-08-28
NO952291D0 (no) 1995-06-09
EP0673378A1 (de) 1995-09-27
EP0673378B1 (de) 1997-03-12
CA2151243A1 (en) 1994-06-23
AU674371B2 (en) 1996-12-19
DE59305812D1 (de) 1997-04-17
ATE150023T1 (de) 1997-03-15
US5654310A (en) 1997-08-05
IL107916A0 (en) 1994-04-12
NO952291L (no) 1995-06-09
JP3490445B2 (ja) 2004-01-26
NZ258558A (en) 1997-06-24
DE4241562A1 (de) 1994-06-16
FI952856A0 (fi) 1995-06-09
AU5628594A (en) 1994-07-04
CN1098414A (zh) 1995-02-08
PL309329A1 (en) 1995-10-02
RU95121818A (ru) 1997-06-10
GR3022980T3 (en) 1997-06-30
ZA939228B (en) 1995-06-09

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