ES2098543T3 - Un proceso para la purificacion de extractos acuosos que contienen proteinas alergenicamente activas, extractos obtenibles de acuerdo con este proceso, asi como su uso. - Google Patents
Un proceso para la purificacion de extractos acuosos que contienen proteinas alergenicamente activas, extractos obtenibles de acuerdo con este proceso, asi como su uso.Info
- Publication number
- ES2098543T3 ES2098543T3 ES92920684T ES92920684T ES2098543T3 ES 2098543 T3 ES2098543 T3 ES 2098543T3 ES 92920684 T ES92920684 T ES 92920684T ES 92920684 T ES92920684 T ES 92920684T ES 2098543 T3 ES2098543 T3 ES 2098543T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- allergenic
- molecular weight
- proteins
- low
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
EL INVENTO SE REFIERE A LA ELIMINACION DE DIVERSOS COMPONENTES DE BAJO PESO MOLECULAR ALERGOLOGICAMENTE IRRELEVANTES DE LOS EXTRACTOS ACUOSOS USUALES EN PROTEINAS ALERGENICAMENTE ACTIVAS DE POLEN DE PLANTAS. SE DESCRIBE LA DESORCION Y ELIMINACION SUBSECUENTE, DESDE EXTRACTOS DE PROTEINAS DE POLEN ALERGENICO PREPARADOS TRADICIONALMENTE, DE PIGMENTOS DE BAJO PESO MOLECULAR Y OTROS COMPUESTOS QUE NORMALMENTE SE RETIENEN POR PODEROSAS FUERZAS ELECTROSTATICA Y/O HIDROFOBICA. LA PREPARACION DE TALES PROTEINAS DE POLEN DEPIGMENTADO NO DISMINUYE SU POTENCIA ALERGENICA O SU ESPECIFICIDAD INMUNOLOGICA. EL INVENTO POSIBILITA LA PRODUCCION DE PROTEINAS DE POLEN ALERGENICO TOTALMENTE ACTIVO DESPROVISTAS DE ADHESION DE SUBSTANCIAS DE BAJO PESO MOLECULAR QUE INTERFIEREN CON SU SEGURIDAD, PRECISION DIAGNOSTICA Y EFICACIA CLINICA. LAS PROTEINAS DE POLEN PURIFICADO REPRESENTAN MATERIALES DE INICIO MEJORADOS POR DERIVACION QUIMICA, ES DECIR, LA PREPARACION DE VACUNAS ATENUADAS DE INMUNOTERAPIA. EL INVENTO TAMBIEN PROPORCIONA PRODUCTOS APROPIADOS PARA LA INVESTIGACION DE LA ESTRUCTURA MOLECULAR DE EPITOPES ALERGENICOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002145169A CA2145169C (en) | 1992-09-21 | 1992-09-21 | A process for the purification of aqueous extracts containing allergenically active proteins, extracts obtainable according to this process as well as their use |
PCT/NL1992/000160 WO1994006821A1 (en) | 1992-09-21 | 1992-09-21 | A process for the purification of aqueous extracts containing allergenically active proteins, extracts obtainable according to this process as well as their use |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2098543T3 true ES2098543T3 (es) | 1997-05-01 |
Family
ID=4155482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92920684T Expired - Lifetime ES2098543T3 (es) | 1992-09-21 | 1992-09-21 | Un proceso para la purificacion de extractos acuosos que contienen proteinas alergenicamente activas, extractos obtenibles de acuerdo con este proceso, asi como su uso. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5770698A (es) |
EP (1) | EP0662080B1 (es) |
AT (1) | ATE148708T1 (es) |
AU (1) | AU675629B2 (es) |
DE (3) | DE69217395T2 (es) |
ES (1) | ES2098543T3 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6350590B1 (en) * | 1997-10-30 | 2002-02-26 | C.B.F. Leti, S.A. | Tolerogenic fragments of natural allergens |
US6562630B2 (en) * | 2000-10-12 | 2003-05-13 | Thomas H. Bryant | Method for preparation and use of preservative-free immunoassay reagents |
IL139308A0 (en) * | 2000-10-26 | 2001-11-25 | Marikovsky Moshe | Peptides from amyloid precursor protein which inhibit tumor growth and metastasis |
SE0004891D0 (sv) * | 2000-12-29 | 2000-12-29 | Pharmacia Diagnostics Ab | Use of a pure allergen component |
US20060269576A1 (en) * | 2005-05-27 | 2006-11-30 | Curalogic, A/S | Non-injection immunotherapy |
EP1872792A1 (en) | 2006-06-29 | 2008-01-02 | Biotech Tools S.A. | A method for the production of hydrolyzed allergen |
KR100828107B1 (ko) * | 2006-09-29 | 2008-05-08 | 주식회사 코스트리 | 저백피 추출물을 함유하는 화장료 조성물 |
US20100278880A1 (en) * | 2008-01-02 | 2010-11-04 | Biotech Tools S.A. | Pharmaceutical formulation for allergen preparation |
EP2258391A1 (en) * | 2009-06-05 | 2010-12-08 | Stallergenes S.A. | Reduction of in vitro genotoxicity of pollen extracts by removal of flavonoids |
RU2572230C2 (ru) | 2010-02-12 | 2015-12-27 | Лабораториос Лети, С.Л. | Способ получения экстракта аллергена |
US9175052B2 (en) | 2013-05-17 | 2015-11-03 | R.J. Reynolds Tobacco Company | Tobacco-derived protein compositions |
EP2974741A1 (en) * | 2014-07-16 | 2016-01-20 | Stallergenes | Composition of allergen extracts having reduced toxicity and method of production thereof |
FR3049866B1 (fr) | 2016-04-07 | 2019-09-06 | Nfl Biosciences | Extrait de feuilles de tabac et utilisation pour le traitement de l'addiction au tabac |
JP2019530702A (ja) | 2016-10-05 | 2019-10-24 | アシット バイオテック エスエー | アレルギーの予防 |
US11408895B1 (en) | 2018-04-09 | 2022-08-09 | Hob Biotech Group Corp., Ltd. | Allergen characterization, potent allergen product formulation, comprehensive allergen reagent, and allergy assay |
US11617789B2 (en) | 2018-11-09 | 2023-04-04 | Jubilant HollisterStier LLC | Process for the preparation of allergenic extracts |
CR20210432A (es) | 2019-01-17 | 2022-01-05 | Leti Pharma S L | Métodos para purificar un extracto de alérgeno |
IT202200011459A1 (it) * | 2022-05-31 | 2023-12-01 | Anallergo S P A | Uso della ultrafiltrazione per la produzione di estratti allergenici purificati |
WO2024089465A2 (en) | 2022-10-24 | 2024-05-02 | Nfl Biosciences | Methods of treatment involving tobacco leaf extracts to help smoking cessation |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8900652A (nl) * | 1989-03-16 | 1990-10-16 | Leti Lab | Primair-toxische stoffen of allergenen, isoleerbaar uit plantaardig materiaal, alsmede werkwijzen ter bereiding ervan en de toepassing ervan. |
-
1992
- 1992-09-21 DE DE69217395T patent/DE69217395T2/de not_active Expired - Lifetime
- 1992-09-21 AT AT92920684T patent/ATE148708T1/de active
- 1992-09-21 US US08/403,832 patent/US5770698A/en not_active Expired - Lifetime
- 1992-09-21 AU AU26486/92A patent/AU675629B2/en not_active Expired
- 1992-09-21 DE DE200512000034 patent/DE122005000034I1/de active Pending
- 1992-09-21 DE DE122005000035C patent/DE122005000035I2/de active Active
- 1992-09-21 ES ES92920684T patent/ES2098543T3/es not_active Expired - Lifetime
- 1992-09-21 EP EP92920684A patent/EP0662080B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5770698A (en) | 1998-06-23 |
EP0662080B1 (en) | 1997-02-05 |
DE69217395D1 (de) | 1997-03-20 |
DE122005000034I1 (de) | 2005-10-20 |
AU2648692A (en) | 1994-04-12 |
DE122005000035I1 (de) | 2005-10-20 |
ATE148708T1 (de) | 1997-02-15 |
DE122005000035I2 (de) | 2008-03-27 |
DE69217395T2 (de) | 1997-05-22 |
AU675629B2 (en) | 1997-02-13 |
EP0662080A1 (en) | 1995-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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