ES2096617T3 - Uso de estafiloquinasa para la preparacion de una composicion farmaceutica para tratar trombosis arterial. - Google Patents
Uso de estafiloquinasa para la preparacion de una composicion farmaceutica para tratar trombosis arterial.Info
- Publication number
- ES2096617T3 ES2096617T3 ES91201670T ES91201670T ES2096617T3 ES 2096617 T3 ES2096617 T3 ES 2096617T3 ES 91201670 T ES91201670 T ES 91201670T ES 91201670 T ES91201670 T ES 91201670T ES 2096617 T3 ES2096617 T3 ES 2096617T3
- Authority
- ES
- Spain
- Prior art keywords
- staphylokinase
- preparation
- pharmaceutical composition
- arterial thrombosis
- treat arterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101710145796 Staphylokinase Proteins 0.000 title abstract 4
- 206010003178 Arterial thrombosis Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 108010023197 Streptokinase Proteins 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 239000003527 fibrinolytic agent Substances 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 208000010125 myocardial infarction Diseases 0.000 abstract 1
- 229960005202 streptokinase Drugs 0.000 abstract 1
- 229960000103 thrombolytic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
EL PRESENTE INVENTO DESCRIBE EL USO DE ESTAFILOQUINASA PARA LA PREPARACION DE UN COMPUESTO FARMACEUTICO PARA TRATAR LA TROMBOSIS ARTERIAL, COMO POR EJEMPLO INFARTO DE MIOCARDIO. ESTA DEMOSTRADO QUE LA ESTAFILOQUINASA PUEDE SER PARTICULARMENTE UTIL COMO AGENTE TROMBOLITICO PARA LA LISIS DE COAGULOS RICOS EN PLAQUETAS. ADEMAS ESTA DEMOSTRADO QUE LA ESTAFILOQUINASA, A DIFERENCIA DE LA ESTREPTOQUINASA NO INDUCE INDUCCION ANTICUERPO TRAS SU ADMINISTRACION REPETIDA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP91201670A EP0525252B1 (en) | 1991-06-28 | 1991-06-28 | Use of staphylokinase for the preparation of a pharmaceutical composition for treating arterial thrombosis |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2096617T3 true ES2096617T3 (es) | 1997-03-16 |
Family
ID=8207747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91201670T Expired - Lifetime ES2096617T3 (es) | 1991-06-28 | 1991-06-28 | Uso de estafiloquinasa para la preparacion de una composicion farmaceutica para tratar trombosis arterial. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5336495A (es) |
EP (1) | EP0525252B1 (es) |
AT (1) | ATE147989T1 (es) |
DE (1) | DE69124370T2 (es) |
DK (1) | DK0525252T3 (es) |
ES (1) | ES2096617T3 (es) |
GR (1) | GR3023211T3 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0621899B1 (de) * | 1991-12-30 | 1996-06-19 | Medac Gesellschaft für klinische Spezialpräparate mbH | Expression signalpeptid-freier staphylokinasen |
US6383483B1 (en) | 1995-01-06 | 2002-05-07 | Désiré José Collen | Staphylokinase derivatives with cysteine substitutions |
US5951980A (en) * | 1995-01-06 | 1999-09-14 | Leuven Research & Development Vzw | Identification, production and use of new staphylokinase derivatives with reduced immunogenicity |
WO1999040198A2 (en) * | 1998-02-04 | 1999-08-12 | Thromb-X N.V. | Identification, production and use of staphylokinase derivatives with reduced immunogenicity and/or reduced clearance |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0135980B1 (ko) * | 1988-04-14 | 1998-04-25 | 구와하라 쥰 | 플라스미노겐 액티베이터 및 혈전용해제 |
-
1991
- 1991-06-28 ES ES91201670T patent/ES2096617T3/es not_active Expired - Lifetime
- 1991-06-28 DE DE69124370T patent/DE69124370T2/de not_active Expired - Lifetime
- 1991-06-28 EP EP91201670A patent/EP0525252B1/en not_active Expired - Lifetime
- 1991-06-28 DK DK91201670.6T patent/DK0525252T3/da active
- 1991-06-28 AT AT91201670T patent/ATE147989T1/de not_active IP Right Cessation
-
1993
- 1993-07-14 US US08/091,885 patent/US5336495A/en not_active Expired - Lifetime
-
1997
- 1997-04-21 GR GR970400872T patent/GR3023211T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3023211T3 (en) | 1997-07-30 |
ATE147989T1 (de) | 1997-02-15 |
DK0525252T3 (da) | 1997-07-28 |
US5336495A (en) | 1994-08-09 |
EP0525252A1 (en) | 1993-02-03 |
DE69124370T2 (de) | 1997-05-15 |
DE69124370D1 (de) | 1997-03-06 |
EP0525252B1 (en) | 1997-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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