ES2094701A1 - Procedimiento para la produccion de antitrombina iii - Google Patents

Procedimiento para la produccion de antitrombina iii

Info

Publication number
ES2094701A1
ES2094701A1 ES09501400A ES9501400A ES2094701A1 ES 2094701 A1 ES2094701 A1 ES 2094701A1 ES 09501400 A ES09501400 A ES 09501400A ES 9501400 A ES9501400 A ES 9501400A ES 2094701 A1 ES2094701 A1 ES 2094701A1
Authority
ES
Spain
Prior art keywords
antithrombin iii
production
affinity chromatography
purified
pasteurization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09501400A
Other languages
English (en)
Other versions
ES2094701B1 (es
Inventor
Debart Pere Ristol
Rodriguez Jesus Fernandez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grifols SA
Original Assignee
Grifols SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols SA filed Critical Grifols SA
Priority to ES9501400A priority Critical patent/ES2094701B1/es
Publication of ES2094701A1 publication Critical patent/ES2094701A1/es
Application granted granted Critical
Publication of ES2094701B1 publication Critical patent/ES2094701B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PRODUCCION DE ANTITROMBINA III. PROCEDIMIENTO DE OBTENCION DE UN CONCENTRADO DE ANTITROMBINA III ALTAMENTE PURIFICADO MEDIANTE UN PROCESO QUE PARTE DE UNA FRACCION O SOBRENADANTE DE PRECIPITACION DEL FRACCIONAMIENTO DE PLASMA HUMANO CON ETANOL EN FRIO, Y MEDIANTE CROMATOGRAFIA DE AFINIDAD SE AISLA Y PURIFICA LA ANTITROMBINA III. EL PRODUCTO OBTENIDO ES INACTIVO DE VIRUS POR PASTEURIZACION, SIENDO POSTERIORMENTE REPURIFICADO POR CROMATOGRAFIA DE AFINIDAD. EL PROCEDIMIENTO PROPORCIONA UN ALTO RENDIMIENTO DE PRODUCCION.
ES9501400A 1995-07-12 1995-07-12 Procedimiento para la produccion de antitrombina iii Expired - Fee Related ES2094701B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9501400A ES2094701B1 (es) 1995-07-12 1995-07-12 Procedimiento para la produccion de antitrombina iii

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9501400A ES2094701B1 (es) 1995-07-12 1995-07-12 Procedimiento para la produccion de antitrombina iii

Publications (2)

Publication Number Publication Date
ES2094701A1 true ES2094701A1 (es) 1997-01-16
ES2094701B1 ES2094701B1 (es) 1997-09-01

Family

ID=8291021

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9501400A Expired - Fee Related ES2094701B1 (es) 1995-07-12 1995-07-12 Procedimiento para la produccion de antitrombina iii

Country Status (1)

Country Link
ES (1) ES2094701B1 (es)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8604744A1 (es) * 1984-09-03 1985-11-01 Landerlan S A Metodo de preparacion de antitrombina iii
EP0252392A2 (en) * 1986-07-11 1988-01-13 Bayer Corporation Viral inactivation and purification of active proteins
WO1995005400A1 (en) * 1993-08-19 1995-02-23 Minnesota Mining And Manufacturing Company Heparin functional affinity supports

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8604744A1 (es) * 1984-09-03 1985-11-01 Landerlan S A Metodo de preparacion de antitrombina iii
EP0252392A2 (en) * 1986-07-11 1988-01-13 Bayer Corporation Viral inactivation and purification of active proteins
WO1995005400A1 (en) * 1993-08-19 1995-02-23 Minnesota Mining And Manufacturing Company Heparin functional affinity supports

Also Published As

Publication number Publication date
ES2094701B1 (es) 1997-09-01

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