ES2117197T3 - Procedimiento para la extraccion y purificacion de alfa1-antitripsina (alfa1-pi) a partir de la fraccion de cohn iv-1. - Google Patents
Procedimiento para la extraccion y purificacion de alfa1-antitripsina (alfa1-pi) a partir de la fraccion de cohn iv-1.Info
- Publication number
- ES2117197T3 ES2117197T3 ES94119902T ES94119902T ES2117197T3 ES 2117197 T3 ES2117197 T3 ES 2117197T3 ES 94119902 T ES94119902 T ES 94119902T ES 94119902 T ES94119902 T ES 94119902T ES 2117197 T3 ES2117197 T3 ES 2117197T3
- Authority
- ES
- Spain
- Prior art keywords
- alfa1
- cohn
- trypsine
- fraction
- extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000605 extraction Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title abstract 2
- 239000002753 trypsin inhibitor Substances 0.000 title abstract 2
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
SE DESCRIBE UN PROCEDIMIENTO PARA LA EXTRACCION Y SUBSIGUIENTE PURIFICACION DE ALFA1-ANTITRIPSINA (ALFA1-PL) A PARTIR DE UNA FRACCION DE COHN IV-1, CUYO PROCESO CONSISTE EN LOS PASOS SIGUIENTES: A) SOLUBILIZACION DE LA PASTA INICIAL CONSTITUIDA POR LA FRACCION DE COHN IV-1 Y UNA PRECIPITACION FRACCIONADA; B) CROMATOGRAFIA DE INTERACCION HIDROFOBA; C) INACTIVACION VIRAL; Y D) OPERACIONES FINALES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITFI930260A IT1271463B (it) | 1993-12-16 | 1993-12-16 | Processo per l'estrazione e purificazione dell'alfal-antitripsina (alfal-pi)dalla frazione iv-1 di cohn. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2117197T3 true ES2117197T3 (es) | 1998-08-01 |
Family
ID=11350681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94119902T Expired - Lifetime ES2117197T3 (es) | 1993-12-16 | 1994-12-16 | Procedimiento para la extraccion y purificacion de alfa1-antitripsina (alfa1-pi) a partir de la fraccion de cohn iv-1. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0717049B1 (es) |
AT (1) | ATE164594T1 (es) |
DE (1) | DE69409390T2 (es) |
ES (1) | ES2117197T3 (es) |
IT (1) | IT1271463B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2318732A (en) | 1996-11-01 | 1998-05-06 | Johnson & Johnson Medical | Wound healing compositions containing alpha-1-antitrypsin |
DE19932782A1 (de) * | 1999-07-14 | 2001-01-18 | Biotest Pharma Gmbh | Verfahren zur chromatographischen Fraktionierung von Plasma oder Serum, so erhaltene Präparate und deren Verwendung |
US7777006B2 (en) | 2002-12-31 | 2010-08-17 | Csl Behring L.L.C. | Method for purification of alpha-1-antitrypsin |
CN111454351A (zh) * | 2019-06-17 | 2020-07-28 | 国药集团上海血液制品有限公司 | 一种α1-抗胰蛋白酶的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2610633B1 (fr) * | 1987-02-05 | 1992-09-18 | Lille Transfusion Sanguine | Procede d'obtention d'un concentre d'a 1-antitrypsine a partir de plasma humain et son utilisation a titre de medicament |
-
1993
- 1993-12-16 IT ITFI930260A patent/IT1271463B/it active IP Right Grant
-
1994
- 1994-12-16 ES ES94119902T patent/ES2117197T3/es not_active Expired - Lifetime
- 1994-12-16 AT AT94119902T patent/ATE164594T1/de active
- 1994-12-16 DE DE69409390T patent/DE69409390T2/de not_active Expired - Lifetime
- 1994-12-16 EP EP94119902A patent/EP0717049B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0717049A1 (en) | 1996-06-19 |
DE69409390D1 (de) | 1998-05-07 |
IT1271463B (it) | 1997-05-28 |
ATE164594T1 (de) | 1998-04-15 |
ITFI930260A1 (it) | 1995-06-16 |
DE69409390T2 (de) | 1998-10-29 |
EP0717049B1 (en) | 1998-04-01 |
ITFI930260A0 (it) | 1993-12-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0966447T3 (da) | Anvendelige små molekyler til behandling af betændelsessygdomme | |
DK0828717T3 (da) | Fremgangsmåde til fremstilling af 3-haloalkyl-1H-pyrazol | |
NO944857D0 (no) | Fluorenyl-inneholdende metallocener, fremgangsmåte for fremstilling derav og fremgangsmåte for polymerisering av olefiner ved anvendelse av metallocenene | |
ATE165345T1 (de) | Sulfonsaeurederivate zur behandlung von viruserkrankungen | |
NO951747L (no) | Fremgangsmåte ved fremstilling av xylitol | |
ES2138603T3 (es) | Procedimiento para el aislamiento de los factores ix, x y ii altamente purificados a partir del complejo protrombinico o del plasma humano. | |
ES2091324T3 (es) | Proceso para la preparacion de aspartama a partir de una dicetopiperazina y nuevos compuestos intermedios y derivados para dicho proceso. | |
ES2117197T3 (es) | Procedimiento para la extraccion y purificacion de alfa1-antitripsina (alfa1-pi) a partir de la fraccion de cohn iv-1. | |
IT8919153A0 (it) | Procedimento di depurazione di componenti polimorfi di genomi complessi. | |
WO1991006521A3 (en) | Chlorofluorohydrocarbon purification process | |
DE69002957T2 (de) | Vakuum-Destillationsverfahren. | |
NO973366L (no) | Fremgangsmåte for behandling av multippel sklerose | |
DK0837677T3 (da) | Bromerede hexahydroxybiphenylderivater | |
NO905012L (no) | Fremgangsmaate til fremstilling av cefemer, oksacefemer ogkarbacefemer og 3-sulfonyloksy-substituerte cefemer, oksacefemer og karbacefemer som utgangsprodukt ved fremgangsmaaten. | |
DE69003963D1 (de) | Vakuum-Destillationsverfahren. | |
MY113294A (en) | A process for the preparation of a virus inactivated fraction containing factor viii by means of chromatographic methods | |
DK0536564T3 (da) | Fremgangsmåde til fremstilling af streptolysin O, intakt streptolysin O fremstillet ved denne fremgangsmåde og dets anvendelse | |
IT1231151B (it) | Metodo di purificazione dei polieteri polioli. | |
SE8901725D0 (sv) | Skylt och saett vid dess framstaellning | |
ITTO920938A0 (it) | Metodo per la produzione di calzature, utilizzante mezzi di lavorazio-ne. | |
FI921844A0 (fi) | Menetelmä 2,6-di-isopropyylifenolin puhdistamiseksi | |
DE69006855D1 (de) | Klärverfahren. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 717049 Country of ref document: ES |