ES2093813T3 - Pelicula universal de fijacion. - Google Patents
Pelicula universal de fijacion.Info
- Publication number
- ES2093813T3 ES2093813T3 ES92900474T ES92900474T ES2093813T3 ES 2093813 T3 ES2093813 T3 ES 2093813T3 ES 92900474 T ES92900474 T ES 92900474T ES 92900474 T ES92900474 T ES 92900474T ES 2093813 T3 ES2093813 T3 ES 2093813T3
- Authority
- ES
- Spain
- Prior art keywords
- binding
- solid
- substrate
- forms
- universal mounting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/553—Metal or metal coated
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Inorganic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Materials For Photolithography (AREA)
- Surface Treatment Of Optical Elements (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
LA INVENCION SE REFIERE A UNA MATRIZ DE LIGAMENTO QUE CONTIENE UN SUBSTRATO DE MATERIAL SOPORTE Y UNOS REACTIVOS DE FASE SOLIDA ABSORBIDOS EN GRUPOS DE ANCLAJE, QUE SE ENCUENTRAN LIGADOS AL MENOS POR MEDIO DE UN COMPUESTO PAREJA DE REACCION LIBRE. EL REACTIVO DE FASE SOLIDA FORMA UNA CAPA AGLOMERANTE DILUIDA Y ESENCIALMENTE HOMOGENEA LATERAL SOBRE LA SUPERFICIE DEL SUBSTRATO. ADEMAS, DE ACUERDO CON EL PROCESO DE ENSAYO DE UNA MUESTRA, SE UTILIZA UN REACTIVO DE FASE SOLIDA QUE FORMA UN COMPONENTE DE LA MATRIZ AGLOMERANTE DESCRITA. LA REACCION DE UNION O ENLACE ESPECIFICA ES DETERMINADA PREFERENTEMENTE POR MEDIO DE TECNICAS DE REFLEXION OPTICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4039677A DE4039677A1 (de) | 1990-12-12 | 1990-12-12 | Universalbindefilm |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2093813T3 true ES2093813T3 (es) | 1997-01-01 |
Family
ID=6420156
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92900474T Expired - Lifetime ES2093813T3 (es) | 1990-12-12 | 1991-12-12 | Pelicula universal de fijacion. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0515615B1 (es) |
JP (1) | JP3071823B2 (es) |
AT (1) | ATE142340T1 (es) |
DE (2) | DE4039677A1 (es) |
ES (1) | ES2093813T3 (es) |
WO (1) | WO1992010757A1 (es) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4219159A1 (de) * | 1992-06-11 | 1993-12-16 | Boehringer Mannheim Gmbh | Selbst assemblierende Monoschicht mit kurzkettigen Linkern |
US5763191A (en) * | 1990-12-12 | 1998-06-09 | Boehringer Mannheim Gmbh | Universal binding film |
US5591578A (en) | 1993-12-10 | 1997-01-07 | California Institute Of Technology | Nucleic acid mediated electron transfer |
US5952172A (en) | 1993-12-10 | 1999-09-14 | California Institute Of Technology | Nucleic acid mediated electron transfer |
US6071699A (en) | 1996-06-07 | 2000-06-06 | California Institute Of Technology | Nucleic acid mediated electron transfer |
US5824473A (en) | 1993-12-10 | 1998-10-20 | California Institute Of Technology | Nucleic acid mediated electron transfer |
DE4435728A1 (de) * | 1994-01-19 | 1995-07-20 | Boehringer Mannheim Gmbh | Biotinsilan-Verbindungen und diese Verbindungen enthaltende Bindematrix |
EP0664452B1 (de) * | 1994-01-19 | 2002-07-31 | Roche Diagnostics GmbH | Biotinsilan-Verbindungen und diese Verbindungen enthaltende Bindematrix |
DE4430023A1 (de) * | 1994-08-24 | 1996-02-29 | Boehringer Mannheim Gmbh | Elektrochemischer Sensor |
US5620850A (en) | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
US6472148B1 (en) | 1994-09-26 | 2002-10-29 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
DE4435727A1 (de) * | 1994-10-06 | 1996-04-11 | Boehringer Mannheim Gmbh | Bindematrix und Analyseelement zur Simultananalyse verschiedener Analyte |
US6444423B1 (en) | 1996-06-07 | 2002-09-03 | Molecular Dynamics, Inc. | Nucleosides comprising polydentate ligands |
SE9602545L (sv) | 1996-06-25 | 1997-12-26 | Michael Mecklenburg | Metod för att diskriminera komplexa biologiska prover |
US7160678B1 (en) | 1996-11-05 | 2007-01-09 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
US7014992B1 (en) * | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
US6096273A (en) * | 1996-11-05 | 2000-08-01 | Clinical Micro Sensors | Electrodes linked via conductive oligomers to nucleic acids |
US7393645B2 (en) | 1996-11-05 | 2008-07-01 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
US7045285B1 (en) | 1996-11-05 | 2006-05-16 | Clinical Micro Sensors, Inc. | Electronic transfer moieties attached to peptide nucleic acids |
US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
DE19715484A1 (de) * | 1997-04-14 | 1998-10-15 | Boehringer Mannheim Gmbh | Verfahren zum Aufbringen von Reagenzspots |
US6013459A (en) | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
US6686150B1 (en) | 1998-01-27 | 2004-02-03 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
EP1051517A2 (en) | 1998-01-27 | 2000-11-15 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
US6303325B1 (en) * | 1998-05-29 | 2001-10-16 | Dade Behring Inc. | Method for detecting analytes |
US6290839B1 (en) | 1998-06-23 | 2001-09-18 | Clinical Micro Sensors, Inc. | Systems for electrophoretic transport and detection of analytes |
US6761816B1 (en) | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
US6740518B1 (en) | 1998-09-17 | 2004-05-25 | Clinical Micro Sensors, Inc. | Signal detection techniques for the detection of analytes |
WO2000024941A1 (en) | 1998-10-27 | 2000-05-04 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
US6833267B1 (en) | 1998-12-30 | 2004-12-21 | Clinical Micro Sensors, Inc. | Tissue collection devices containing biosensors |
US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
DE19924606A1 (de) * | 1999-05-28 | 2000-11-30 | Graffinity Pharm Design Gmbh | Ligand-Anker-Konjugate |
AU779220B2 (en) | 1999-07-26 | 2005-01-13 | Clinical Micro Sensors, Inc. | Sequence determination of nucleic acids using electronic detection |
US6753143B2 (en) | 2000-05-01 | 2004-06-22 | Clinical Micro Sensors, Inc. | Target analyte detection using asymmetrical self-assembled monolayers |
EP1297338B1 (en) * | 2000-06-05 | 2007-04-18 | Novartis Vaccines and Diagnostics, Inc. | Microarrays for performing proteomic analyses |
US7148058B2 (en) | 2000-06-05 | 2006-12-12 | Chiron Corporation | Protein microarrays on mirrored surfaces for performing proteomic analyses |
US7153682B2 (en) | 2000-06-05 | 2006-12-26 | Chiron Corporation | Microarrays on mirrored substrates for performing proteomic analyses |
US6984522B2 (en) | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
JP3261125B1 (ja) | 2001-07-06 | 2002-02-25 | 有限会社大東土木 | 摩砕機 |
EP1489415A4 (en) | 2002-03-11 | 2006-02-22 | Toudai Tlo Ltd | POLY (ETHYLENE OXIDE) SURFACE WITH BRUSH TYPE STRUCTURE HAVING HIGH DENSITY |
WO2004048552A2 (en) | 2002-11-21 | 2004-06-10 | Celltech R & D, Inc. | Modulating immune responses |
US7842475B2 (en) * | 2008-01-08 | 2010-11-30 | Siemens Healthcare Diagnostics Inc. | Stabilization of solid support assay reagents |
JP2022099742A (ja) * | 2020-12-23 | 2022-07-05 | 昇陽國際半導體股▲ふん▼有限公司 | バイオプローブのリンカー |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0112721B1 (en) * | 1982-12-21 | 1988-05-18 | Ares-Serono N.V. | Assay technique |
WO1987006007A1 (fr) * | 1986-03-28 | 1987-10-09 | Toray Industries, Inc. | Substance physiologiquement active immobilisee |
GB8618133D0 (en) * | 1986-07-24 | 1986-09-03 | Pa Consulting Services | Biosensors |
CA1320718C (en) * | 1987-06-08 | 1993-07-27 | Richard Frederick Hammen | Chromatographic material |
GB2217447A (en) * | 1988-04-21 | 1989-10-25 | Atomic Energy Authority Uk | Bonding to metal surfaces |
-
1990
- 1990-12-12 DE DE4039677A patent/DE4039677A1/de not_active Withdrawn
-
1991
- 1991-12-12 JP JP04502451A patent/JP3071823B2/ja not_active Expired - Lifetime
- 1991-12-12 WO PCT/EP1991/002393 patent/WO1992010757A1/de active IP Right Grant
- 1991-12-12 DE DE59108149T patent/DE59108149D1/de not_active Expired - Lifetime
- 1991-12-12 EP EP92900474A patent/EP0515615B1/de not_active Expired - Lifetime
- 1991-12-12 ES ES92900474T patent/ES2093813T3/es not_active Expired - Lifetime
- 1991-12-12 AT AT92900474T patent/ATE142340T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE59108149D1 (de) | 1996-10-10 |
JPH05502515A (ja) | 1993-04-28 |
WO1992010757A1 (de) | 1992-06-25 |
EP0515615A1 (de) | 1992-12-02 |
DE4039677A1 (de) | 1992-06-17 |
ATE142340T1 (de) | 1996-09-15 |
JP3071823B2 (ja) | 2000-07-31 |
EP0515615B1 (de) | 1996-09-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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