ES2092116T3 - Policarbonatos y sus usos para la preparacion de matrices bioerosionables. - Google Patents

Policarbonatos y sus usos para la preparacion de matrices bioerosionables.

Info

Publication number
ES2092116T3
ES2092116T3 ES92911499T ES92911499T ES2092116T3 ES 2092116 T3 ES2092116 T3 ES 2092116T3 ES 92911499 T ES92911499 T ES 92911499T ES 92911499 T ES92911499 T ES 92911499T ES 2092116 T3 ES2092116 T3 ES 2092116T3
Authority
ES
Spain
Prior art keywords
compounds
formula
halifatic
integer
straight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92911499T
Other languages
English (en)
Inventor
Paolo Ferruti
Elisabetta Ranucci
Fabio Bignotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mediolanum Farmaceutici SpA
Original Assignee
Mediolanum Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farmaceutici SpA filed Critical Mediolanum Farmaceutici SpA
Application granted granted Critical
Publication of ES2092116T3 publication Critical patent/ES2092116T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
    • C08G64/02—Aliphatic polycarbonates
    • C08G64/0208—Aliphatic polycarbonates saturated
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
    • C08G64/18—Block or graft polymers
    • C08G64/183—Block or graft polymers containing polyether sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
    • C08G64/20—General preparatory processes
    • C08G64/38—General preparatory processes using other monomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyethers (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

SE PRESENTAN POLICARBONATOS DE LA FORMULA I EN LA QUE A ES UN ENTERO ENTRE 2 Y 300; R1 Y R2 QUE PUEDEN SER IGUALES O DIFERENTES, SON UNA CADENA HALIFATICA O ALICILICA RECTA O RAMIFICADA QUE TIENE ENTRE 2 Y 18 ATOMOS DE CARBONO; O R1 Y E2 SON UN RESIDUO DE POLIOXIALQUILENO DE LA FORMULA II EN LA QUE R3 ES HIDROGENO O METIL, N ES UN ENTERO ENTRE 1 Y 3 Y M ES UN ENTERO ENTRE 1 Y 200, O UN RESIDUO DE POLIESTER DE LA FORMULA III, EN LA QUE X ES Y SON ENTEROS ENTRE 1 Y 50, R4 Y R5, QUE PUEDEN SER IGUALES O DIFERENTES, SON CADENAS DE HIDROCARBONO HALIFATICO RECTAS O RAMIFICADAS QUE TIENEN ENTRE 1 Y 4 ATOMOS DE CARBONO, R6 ES UNA CADENA RECTA O RAMIFICADA HALIFATICA O HALICICLICA QUE TIENEN ENTRE 2 Y 18 ATOMOS DE CARBONO, O UN RESIDUO DE POLIOXIALQUILENO DE LA FORMULA II, TENIENDO EN CUENTA QUE LOS DOS GRUPOS -R4-COO Y R5-COO SE ENCUENTRAN DISTRIBUIDOS ALEATORIAMENTE EN EL RESIDUO DE POLIESTER, X E Y SE ENCUENTRAN EN CUALQUIER POSIBLE RELACION ENTRE 0 Y 100, LOS COMPUESTOS SE SINTETIZAN MEDIANTE LAREACCION DE LOS COMPUESTOS DE DIHIDROXIDO CON 1,1''-CARBONILDIIMIDAZOLA. ESTOS COMPUESTOS SON UTILES EN LA PREPARACION DE MATRICES BIOEROSIONABLES PARA COMPUESTOS BIOLOGICAMENTE ACTIVOS.
ES92911499T 1991-06-14 1992-06-05 Policarbonatos y sus usos para la preparacion de matrices bioerosionables. Expired - Lifetime ES2092116T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911645A IT1248061B (it) 1991-06-14 1991-06-14 Policarbonati e loro uso per la preparazione di matrici bioerodibili

Publications (1)

Publication Number Publication Date
ES2092116T3 true ES2092116T3 (es) 1996-11-16

Family

ID=11360124

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92911499T Expired - Lifetime ES2092116T3 (es) 1991-06-14 1992-06-05 Policarbonatos y sus usos para la preparacion de matrices bioerosionables.

Country Status (11)

Country Link
US (1) US5463012A (es)
EP (1) EP0588853B1 (es)
JP (1) JP3175772B2 (es)
AT (1) ATE143030T1 (es)
AU (1) AU1910892A (es)
DE (1) DE69213937T2 (es)
DK (1) DK0588853T3 (es)
ES (1) ES2092116T3 (es)
GR (1) GR3021602T3 (es)
IT (1) IT1248061B (es)
WO (1) WO1992022600A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110787A0 (en) 1993-08-27 1994-11-11 Sandoz Ag Biodegradable polymer, its preparation and pharmaceutical composition containing it
IT1266775B1 (it) * 1993-11-05 1997-01-21 Mediolanum Farmaceutici Srl Poliesterepolicarbonati ad alto peso molecolare e loro uso per la preparazione di matrici bioerodibili
ZA978537B (en) 1996-09-23 1998-05-12 Focal Inc Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
FR2777895A1 (fr) * 1998-04-28 1999-10-29 Debio Rech Pharma Sa Polymere sequence non-reticule,procede pour sa preparation, et ses utilisations
US6348558B1 (en) 1999-12-10 2002-02-19 Shearwater Corporation Hydrolytically degradable polymers and hydrogels made therefrom
US7074878B1 (en) * 1999-12-10 2006-07-11 Harris J Milton Hydrolytically degradable polymers and hydrogels made therefrom
JP4642882B2 (ja) * 2007-07-19 2011-03-02 花王株式会社 ポリエーテルポリカーボネート
FR2941700B1 (fr) 2009-02-02 2012-03-16 Arkema France Procede de synthese d'un alliage de copolymere a blocs presentant des proprietes antistatiques ameliorees.
KR101251017B1 (ko) 2011-03-03 2013-04-03 연세대학교 산학협력단 할로겐화 폴리카보네이트의 제조방법, 할로겐화 폴리카보네이트, 단량체의 제조방법 및 그 단량체
FR3073851B1 (fr) 2017-11-17 2019-11-08 Arkema France Film imper-respirant souple et etirable a base de copolymere a blocs
FR3073852B1 (fr) 2017-11-17 2019-10-11 Arkema France Mousse de copolymere a blocs
FR3073848B1 (fr) 2017-11-17 2020-11-13 Arkema France Copolymere a blocs presentant des resistances ameliorees a l'abrasion et a la dechirure
FR3073867B1 (fr) 2017-11-17 2019-11-08 Arkema France Materiau textile souple etirable et anti-bouloches a base de copolymere a blocs
FR3096683B1 (fr) 2019-05-27 2022-03-04 Arkema France copolyesteramide auto-ignifugé
FR3096684B1 (fr) 2019-05-29 2022-03-04 Arkema France Copolymère à blocs à résistance améliorée au sébum
CN111848933B (zh) * 2020-06-28 2022-08-23 吴君宇 一种可降解共聚酯的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1208196A (fr) * 1958-12-11 1960-02-22 Basf Ag Procédé pour la production de polyesters et de polyamides de l'anhydride carbonique à poids moléculaire élevé
JPS5190323A (es) * 1975-02-07 1976-08-07
US4105641A (en) * 1975-05-27 1978-08-08 Bayer Aktiengesellschaft Process for the preparation of aliphatic polycarbonates and polyurethanes therefrom
JPS5980454A (ja) * 1982-10-28 1984-05-09 Sumitomo Chem Co Ltd 制振性複合体
DE3607625A1 (de) * 1986-03-07 1987-09-10 Bayer Ag Verfahren zur herstellung von linearen aliphatischen polycarbonaten
US4665136A (en) * 1986-04-07 1987-05-12 Air Products And Chemicals, Inc. Process for producing novel block alkylene polycarbonate copolymers
US4716203A (en) * 1986-09-05 1987-12-29 American Cyanamid Company Diblock and triblock copolymers
WO1989005664A1 (en) * 1987-12-17 1989-06-29 Allied-Signal Inc. Medical devices fabricated from homopolymers and copolymers having recurring carbonate units
EP0335416A3 (en) * 1988-04-01 1990-12-27 Hodogaya Chemical Co., Ltd. Modified polyoxytetramethylene glycol and processes for its production
US5260367A (en) * 1989-02-15 1993-11-09 Toda Kogyo Corp. Vehicle damping sheet
JPH0751339B2 (ja) * 1989-04-12 1995-06-05 財団法人鉄道総合技術研究所 複合型制振材および振動体の制振施工法
DE3937272A1 (de) * 1989-11-09 1991-05-16 Boehringer Ingelheim Kg Neue copolymere aus trimethylencarbonat und optisch inaktiven laktiden

Also Published As

Publication number Publication date
ITMI911645A1 (it) 1992-12-14
DK0588853T3 (es) 1997-02-24
JP3175772B2 (ja) 2001-06-11
WO1992022600A1 (en) 1992-12-23
EP0588853A1 (en) 1994-03-30
JPH06508383A (ja) 1994-09-22
EP0588853B1 (en) 1996-09-18
DE69213937T2 (de) 1997-03-06
DE69213937D1 (de) 1996-10-24
US5463012A (en) 1995-10-31
GR3021602T3 (en) 1997-02-28
ITMI911645A0 (it) 1991-06-14
AU1910892A (en) 1993-01-12
ATE143030T1 (de) 1996-10-15
IT1248061B (it) 1995-01-05

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