ES2090411T3 - Procedimiento para la preparacion enzimatica de derivados de cefalosporano. - Google Patents
Procedimiento para la preparacion enzimatica de derivados de cefalosporano.Info
- Publication number
- ES2090411T3 ES2090411T3 ES92109410T ES92109410T ES2090411T3 ES 2090411 T3 ES2090411 T3 ES 2090411T3 ES 92109410 T ES92109410 T ES 92109410T ES 92109410 T ES92109410 T ES 92109410T ES 2090411 T3 ES2090411 T3 ES 2090411T3
- Authority
- ES
- Spain
- Prior art keywords
- cephalosporan
- derivatives
- procedure
- enzymatic preparation
- cooh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000002255 enzymatic effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 102000004316 Oxidoreductases Human genes 0.000 abstract 1
- 108090000854 Oxidoreductases Proteins 0.000 abstract 1
- 241000223252 Rhodotorula Species 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000007833 oxidative deamination reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12N9/0024—D-Amino acid oxidase (1.4.3.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/06—Cephalosporin C; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
SE DESCRIBE UN PROCESO PARA LA PRODUCCION ENZIMATICA DE DERIVADOS DE CEFALOSPORANO, O DE SUS SALES, QUE TIENEN LA FORMULA (I): EN DONDE R REPRESENTA UN GRUPO -CO-COOH O -COOH Y R'' ES H, OH O O-CO-R", SIENDO R" UN GRUPO ALKILO C1-C4, INCLUIDA LA DESAMINACION OXIDATIVA DE LOS COMPUESTOS, O DE SUS SALES, QUE TIENEN LA FORMULA (II): ANTE LA PRESENCIA DE UN MICROORGANISMO DEL TIPO RHODOTORULA O UNA OXIDASA D-AMINOACIDA DERIVADA DEL MISMO, CON FORMA LIBRE O INMOVILIZADA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI911509A IT1247964B (it) | 1991-06-03 | 1991-06-03 | Processo per la preparazione enzimatica di derivati cefalosporanici |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2090411T3 true ES2090411T3 (es) | 1996-10-16 |
Family
ID=11360034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92109410T Expired - Lifetime ES2090411T3 (es) | 1991-06-03 | 1992-06-03 | Procedimiento para la preparacion enzimatica de derivados de cefalosporano. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5296358A (es) |
| EP (1) | EP0517200B1 (es) |
| JP (1) | JP3131024B2 (es) |
| AT (1) | ATE141333T1 (es) |
| CA (1) | CA2070083A1 (es) |
| DE (1) | DE69212713T2 (es) |
| DK (1) | DK0517200T3 (es) |
| ES (1) | ES2090411T3 (es) |
| IT (1) | IT1247964B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5597704A (en) * | 1995-05-01 | 1997-01-28 | Food Industry Research And Development Institute | Bioconversion of cephalosporin C to glutaryl-7-aminocephalosporanic acid |
| ES2109194B1 (es) * | 1996-04-22 | 1998-07-16 | Antibioticos Sa | Un procedimiento para producir la enzima d-aminoacido oxidasa de rhodotorula gracilis en celulas hospedantes. |
| JPH10295392A (ja) * | 1997-04-22 | 1998-11-10 | Kanegafuchi Chem Ind Co Ltd | Ｌ−アルリジンアセタールの製造方法 |
| US5877013A (en) * | 1997-07-31 | 1999-03-02 | Food Industry Research And Development Institute | Rhodosporidium D-amino acid oxidase |
| DE19937187A1 (de) * | 1999-08-06 | 2001-03-01 | Qiagen Gmbh | Automatisierte Proteinreinigung im Multiwellformat durch Vakuumfiltration |
| CN1531539A (zh) | 2001-04-19 | 2004-09-22 | ��ŷ�����¶����ǹɷ�����˾ | 用α-酮酸衍生物制备头孢烷酸衍生物的酶促方法 |
| KR100512774B1 (ko) * | 2001-10-06 | 2005-09-07 | 종근당바이오 주식회사 | 7-아미노세팔로스포란산의 제조를 위한 세팔로스포린ｃ배양액의 전처리방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1121308A (en) * | 1964-10-30 | 1968-07-24 | Glaxo Lab Ltd | Cephalosporins |
| GB1272769A (en) * | 1968-08-02 | 1972-05-03 | Glaxo Lab Ltd | Improvements in or relating to cephalosporin derivatives |
| GB1385685A (en) * | 1971-04-21 | 1975-02-26 | Glaxo Lab Ltd | Cephalosporin derivatives |
| GB1474519A (es) * | 1973-05-14 | 1977-05-25 | ||
| DE4028119C1 (es) * | 1990-09-05 | 1991-12-05 | Hoechst Ag, 6230 Frankfurt, De |
-
1991
- 1991-06-03 IT ITMI911509A patent/IT1247964B/it active IP Right Grant
-
1992
- 1992-05-29 CA CA002070083A patent/CA2070083A1/en not_active Abandoned
- 1992-06-02 JP JP04140842A patent/JP3131024B2/ja not_active Expired - Fee Related
- 1992-06-03 ES ES92109410T patent/ES2090411T3/es not_active Expired - Lifetime
- 1992-06-03 EP EP92109410A patent/EP0517200B1/en not_active Expired - Lifetime
- 1992-06-03 DE DE69212713T patent/DE69212713T2/de not_active Expired - Fee Related
- 1992-06-03 DK DK92109410.8T patent/DK0517200T3/da active
- 1992-06-03 AT AT92109410T patent/ATE141333T1/de not_active IP Right Cessation
- 1992-06-03 US US07/893,048 patent/US5296358A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0517200B1 (en) | 1996-08-14 |
| CA2070083A1 (en) | 1992-12-04 |
| US5296358A (en) | 1994-03-22 |
| ITMI911509A0 (it) | 1991-06-03 |
| IT1247964B (it) | 1995-01-05 |
| ATE141333T1 (de) | 1996-08-15 |
| EP0517200A2 (en) | 1992-12-09 |
| DK0517200T3 (da) | 1996-09-02 |
| EP0517200A3 (en) | 1993-03-03 |
| DE69212713T2 (de) | 1997-03-06 |
| DE69212713D1 (de) | 1996-09-19 |
| JP3131024B2 (ja) | 2001-01-31 |
| ITMI911509A1 (it) | 1992-12-03 |
| JPH05244991A (ja) | 1993-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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