ES2089665T3 - Terazosina polimorfa y composicion farmaceutica. - Google Patents
Terazosina polimorfa y composicion farmaceutica.Info
- Publication number
- ES2089665T3 ES2089665T3 ES93115607T ES93115607T ES2089665T3 ES 2089665 T3 ES2089665 T3 ES 2089665T3 ES 93115607 T ES93115607 T ES 93115607T ES 93115607 T ES93115607 T ES 93115607T ES 2089665 T3 ES2089665 T3 ES 2089665T3
- Authority
- ES
- Spain
- Prior art keywords
- terazosin
- polymorphic
- pharmaceutical composition
- new
- polymorph
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- VCKUSRYTPJJLNI-UHFFFAOYSA-N terazosin Chemical compound N=1C(N)=C2C=C(OC)C(OC)=CC2=NC=1N(CC1)CCN1C(=O)C1CCCO1 VCKUSRYTPJJLNI-UHFFFAOYSA-N 0.000 title 1
- 229960001693 terazosin Drugs 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000009246 food effect Effects 0.000 abstract 1
- 235000021471 food effect Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE DESCRIBE UN NUEVO POLIMORFO CRISTALINO ANHIDRIDO DE MONOHIDROCLORURO DE 1 INIL) PO QUE FORMULACIONES FARMACEUTICAS QUE CONTIENEN EL COMPONENTE. EL NUEVO POLIMORFO EXHIBE UN EFECTO DE COMIDA DISMINUIDA CUANDO SE ADMINISTRA A SUJETOS HUMANOS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5491793A | 1993-04-29 | 1993-04-29 | |
| US08/090,721 US5294615A (en) | 1993-04-29 | 1993-07-13 | Terazosin polymorph and pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2089665T3 true ES2089665T3 (es) | 1996-10-01 |
Family
ID=26733641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93115607T Expired - Lifetime ES2089665T3 (es) | 1993-04-29 | 1993-09-28 | Terazosina polimorfa y composicion farmaceutica. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5294615A (es) |
| EP (1) | EP0623612B1 (es) |
| JP (1) | JP2755895B2 (es) |
| DE (1) | DE69300913T2 (es) |
| DK (1) | DK0623612T3 (es) |
| ES (1) | ES2089665T3 (es) |
| GR (1) | GR3018433T3 (es) |
| HK (1) | HK124397A (es) |
| MX (1) | MX9306196A (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5596109A (en) * | 1992-03-24 | 1997-01-21 | Smithkline Beecham Corporation | N-t-butyl-androst-3,5-diene-17β-carboxamide-3-carboxylic acid polymorph A |
| US5412095A (en) * | 1993-04-29 | 1995-05-02 | Abbott Laboratories | Terazosin monohydrochloride and processes and intermediate for its production |
| JPH07206857A (ja) * | 1993-12-28 | 1995-08-08 | Synthelabo Sa | アルフゾシン塩酸塩の二水和物 |
| US5504207A (en) * | 1994-10-18 | 1996-04-02 | Abbott Laboratories | Process and intermediate for the preparation of terazosin hydrochloride dihydrate |
| US5587377A (en) * | 1995-10-24 | 1996-12-24 | Invamed, Inc. | Terazosin crystalline polymorph and pharmaceutical compositions thereof |
| DE19546573A1 (de) * | 1995-12-13 | 1997-06-19 | Uetikon Chemie Gmbh | Kristallines Polymorph von Terazosin-Hydrochlorid, sowie Verfahren zu seiner Herstellung |
| US5952003A (en) * | 1996-08-01 | 1999-09-14 | Novartis Corporation | Terazosin capsules |
| IT1286789B1 (it) * | 1996-11-29 | 1998-07-17 | Alfa Chem Ital | Processo per la produzione della forma i del terazosin monocloridato anidro |
| IT1286790B1 (it) * | 1996-11-29 | 1998-07-17 | Alfa Chem Ital | Processo per la produzione della forma i del terazosin monocloridrato anidro |
| EP0849265A1 (de) * | 1996-12-20 | 1998-06-24 | HEUMANN PHARMA GmbH | Neue polymorphe Form von Doxazosin-Mesylat (Form II) |
| EP0849266B8 (de) * | 1996-12-20 | 2007-10-03 | Heumann PCS GmbH | Neue polymorphe Form von Doxazosinmesylat (Form III) |
| EP0849264A1 (de) * | 1996-12-20 | 1998-06-24 | HEUMANN PHARMA GmbH | Neue polymorphe Form von doxazosinmesylat (Form I) |
| US6248888B1 (en) | 1997-11-14 | 2001-06-19 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of terazosin hydrochloride dihydrate |
| UA72922C2 (uk) * | 1999-08-03 | 2005-05-16 | Ліллі Айкос Ллк | ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ З <font face="Symbol">b</font>-КАРБОЛІНОМ (ВАРІАНТИ) ТА СПОСІБ ЛІКУВАННЯ СЕКСУАЛЬНОЇ ДИСФУНКЦІЇ |
| US6200573B1 (en) | 1999-12-03 | 2001-03-13 | Starcor Pharmaceuticals, Inc. | Method of medical management for lower urinary tract symptoms and benign prostatic hyperplasia |
| DE10000792A1 (de) * | 2000-01-11 | 2001-07-19 | Bernhard C Lippold | Formulierungen von Wirkstoffen in Form einer festen Dispersion |
| ATE405577T1 (de) * | 2000-11-17 | 2008-09-15 | Lilly Co Eli | Lactam dipeptid und dessen verwendung zur inhibierung der beta-amyloid peptid frisetzung |
| US20030138483A1 (en) * | 2001-05-25 | 2003-07-24 | Sergio Petriconi | Soft elastic capsules and compositions thereof |
| US8496960B2 (en) * | 2001-10-23 | 2013-07-30 | Purdue Pharma L.P. | Terazosin transdermal device and methods |
| IL163666A0 (en) | 2002-02-22 | 2005-12-18 | New River Pharmaceuticals Inc | Active agent delivery systems and methods for protecting and administering active agents |
| TWI353979B (en) | 2002-04-10 | 2011-12-11 | Nippon Zoki Pharmaceutical Co | Novel crystal form of 5-hydroxy-1-methylhydantoin |
| US7097967B2 (en) * | 2002-10-24 | 2006-08-29 | Lg Life Sciences Ltd. | Method of predicting drug-food interaction |
| KR20040076203A (ko) * | 2003-02-24 | 2004-08-31 | 주식회사 엘지생명과학 | 음식물-약물 상호작용을 방지하기 위한 경구 투여용약제학적 조성물 및 방법 |
| AU2007286186A1 (en) * | 2006-08-08 | 2008-02-21 | Auspex Pharmaceuticals, Inc. | Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects |
| CN102321563B (zh) | 2011-10-24 | 2013-04-03 | 江南大学 | 一株拟无枝酸菌及利用其全细胞转化制备香草醛的方法 |
| US9096428B2 (en) * | 2013-03-08 | 2015-08-04 | Taiwan Semiconductor Manufacturing Company, Ltd. | Methods and apparatus for MEMS structure release |
| US11224572B1 (en) | 2020-08-17 | 2022-01-18 | Novitium Pharma LLC | Stable oral liquid composition of terazosin |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4026894A (en) * | 1975-10-14 | 1977-05-31 | Abbott Laboratories | Antihypertensive agents |
| GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
| US5122514A (en) * | 1990-04-23 | 1992-06-16 | Abbott Laboratories | Psoriasis treatment |
| US5212176A (en) * | 1990-06-29 | 1993-05-18 | Abbott Laboratories | R(+)-terazosin |
| JP2652272B2 (ja) * | 1990-12-31 | 1997-09-10 | 住化ファインケム株式会社 | 1−(4−アミノ−6,7−ジメトキシ−2−キナゾリニル)−4−(2−テトラヒドロフロイル)ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法 |
-
1993
- 1993-07-13 US US08/090,721 patent/US5294615A/en not_active Expired - Fee Related
- 1993-09-28 EP EP93115607A patent/EP0623612B1/en not_active Revoked
- 1993-09-28 ES ES93115607T patent/ES2089665T3/es not_active Expired - Lifetime
- 1993-09-28 DK DK93115607.9T patent/DK0623612T3/da active
- 1993-09-28 DE DE69300913T patent/DE69300913T2/de not_active Revoked
- 1993-10-05 MX MX9306196A patent/MX9306196A/es not_active IP Right Cessation
- 1993-10-14 JP JP5257010A patent/JP2755895B2/ja not_active Expired - Lifetime
-
1994
- 1994-01-06 US US08/178,184 patent/US5362730A/en not_active Expired - Fee Related
-
1995
- 1995-12-15 GR GR950403563T patent/GR3018433T3/el unknown
-
1997
- 1997-06-26 HK HK124397A patent/HK124397A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0623612A1 (en) | 1994-11-09 |
| US5294615A (en) | 1994-03-15 |
| GR3018433T3 (en) | 1996-03-31 |
| DE69300913D1 (de) | 1996-01-11 |
| HK124397A (en) | 1997-09-12 |
| JP2755895B2 (ja) | 1998-05-25 |
| DK0623612T3 (da) | 1996-02-05 |
| EP0623612B1 (en) | 1995-11-29 |
| DE69300913T2 (de) | 1996-05-02 |
| MX9306196A (es) | 1994-01-31 |
| US5362730A (en) | 1994-11-08 |
| JPH06312984A (ja) | 1994-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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