ES2088992T3 - Metodo para determinar los niveles de factores de coagulacion intrinsecos y extrinsecos y proteina c. - Google Patents
Metodo para determinar los niveles de factores de coagulacion intrinsecos y extrinsecos y proteina c.Info
- Publication number
- ES2088992T3 ES2088992T3 ES90313862T ES90313862T ES2088992T3 ES 2088992 T3 ES2088992 T3 ES 2088992T3 ES 90313862 T ES90313862 T ES 90313862T ES 90313862 T ES90313862 T ES 90313862T ES 2088992 T3 ES2088992 T3 ES 2088992T3
- Authority
- ES
- Spain
- Prior art keywords
- reaction rate
- clot formation
- protein
- intrinsic
- levels
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/809—Multifield plates or multicontainer arrays
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/452,802 US5169786A (en) | 1989-12-19 | 1989-12-19 | Method of determining levels of extrinsic and intrinsic clotting factors and protein c |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2088992T3 true ES2088992T3 (es) | 1996-10-01 |
Family
ID=23797999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90313862T Expired - Lifetime ES2088992T3 (es) | 1989-12-19 | 1990-12-18 | Metodo para determinar los niveles de factores de coagulacion intrinsecos y extrinsecos y proteina c. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5169786A (de) |
EP (1) | EP0434377B1 (de) |
AT (1) | ATE126894T1 (de) |
CA (1) | CA2032561C (de) |
DE (1) | DE69021849T2 (de) |
DK (1) | DK0434377T3 (de) |
ES (1) | ES2088992T3 (de) |
GR (1) | GR1001222B (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6114135A (en) * | 1991-11-08 | 2000-09-05 | Goldstein; Sheldon | Multiple coagulation test system and method of using a multiple coagulation test system |
SE470274B (sv) * | 1991-11-13 | 1993-12-20 | Bjoern Dahlbaeck | Användning av en in vitro-metod för diagnos av blodkoagulationssjukdomar |
DE69207607T3 (de) * | 1991-11-13 | 2006-07-06 | T.A.C. Thrombosis And Coagulation Ab | Verfahren zur diagnose von störungen der blutgerinnung |
ES2223043T3 (es) * | 1992-11-12 | 2005-02-16 | Sheldon Goldstein | Dispositivo y procedimiento de ensayos de coagulacion multiples. |
DE69411898T3 (de) * | 1993-01-29 | 2004-07-08 | T.A.C. Thrombosis And Coagulation Ab | Neue antikoagulant-cofaktor aktivität |
US5378431A (en) * | 1993-06-14 | 1995-01-03 | Becton, Dickinson And Company | Dual pathway clotting enhancer for blood collection tube |
ATE177536T1 (de) * | 1993-06-30 | 1999-03-15 | Diagnostische Forsch Stiftung | Messung des aktivierten partiellen thromboplastinzeit (aptt) in einer einstufen- reaktion |
EP0656424B1 (de) * | 1993-12-03 | 2002-02-06 | Baxter Aktiengesellschaft | Test zur Bestimmung der Empfindlichkeit gegenüber aktiviertem Protein C |
US5705395A (en) * | 1994-11-14 | 1998-01-06 | The Scripps Research Institute | Method for diagnosis of thrombotic disorders |
US6867045B1 (en) | 1994-11-14 | 2005-03-15 | The Scripps Research Institute | Method for diagnosis of thrombotic disorders |
US5708591A (en) | 1995-02-14 | 1998-01-13 | Akzo Nobel N.V. | Method and apparatus for predicting the presence of congenital and acquired imbalances and therapeutic conditions |
US6898532B1 (en) | 1995-06-07 | 2005-05-24 | Biomerieux, Inc. | Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample |
US6321164B1 (en) * | 1995-06-07 | 2001-11-20 | Akzo Nobel N.V. | Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade |
US6429017B1 (en) * | 1999-02-04 | 2002-08-06 | Biomerieux | Method for predicting the presence of haemostatic dysfunction in a patient sample |
US5780255A (en) * | 1995-06-09 | 1998-07-14 | Instrumentation Laboratory, S.P.A. | Protein C pathway screening test |
US20030143759A1 (en) * | 1995-10-20 | 2003-07-31 | Bjorn Dahlback | Assays for determining anticoagulant cofactor activity |
US5766869A (en) * | 1995-11-30 | 1998-06-16 | Ahs Hospital Corp. | Factor V ratio blood test for susceptibility to thromboembolism |
US5839443A (en) * | 1996-05-16 | 1998-11-24 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting thrombosis in a patient whose blood is subjected to extracorporeal circulation |
US6379975B1 (en) | 1996-11-27 | 2002-04-30 | T.A.C. Thrombosis And Coagulation Aktiebolag | Methods and reagents for determining protein S |
DE19724239A1 (de) * | 1997-06-09 | 1998-12-10 | Max Planck Gesellschaft | Dysprothrombinämie |
US6502040B2 (en) | 1997-12-31 | 2002-12-31 | Biomerieux, Inc. | Method for presenting thrombosis and hemostasis assay data |
US6194394B1 (en) * | 1998-07-01 | 2001-02-27 | Sigma-Aldrich Co. | Coagulation controls for prothrombin time (PT) and activated partial thromboplastin time (APTT) assays |
US6524861B1 (en) | 1999-01-22 | 2003-02-25 | Medical Laboratory Automation, Inc. | Blood coagulation analyzer |
CA2362055C (en) * | 1999-02-04 | 2010-07-20 | Akzo Nobel N.V. | A method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample |
US20050250688A1 (en) * | 1999-04-01 | 2005-11-10 | The Trustees Of Columbia University In The City Of New York | Methods for treating an ischemic disorder and improving stroke outcome |
US20020132370A1 (en) * | 2000-02-23 | 2002-09-19 | Lassen Michael Rud | Detection of a blood coagulation activity marker in a body fluid sample |
US7179612B2 (en) | 2000-06-09 | 2007-02-20 | Biomerieux, Inc. | Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality |
US6855509B2 (en) | 2000-12-19 | 2005-02-15 | Instrumentation Laboratory Company | Protein S functional assay and kit therefor |
US7148067B2 (en) * | 2004-08-31 | 2006-12-12 | The Board Of Trustees Of The University Of Illinois | Thromboplastin reagents |
CN101151533A (zh) * | 2005-02-16 | 2008-03-26 | 伊利诺斯大学理事会 | 基于金属螯合脂质的促凝血剂 |
CA2600907C (en) * | 2005-03-04 | 2016-06-28 | The Board Of Trustees Of The University Of Illinois | Coagulation and fibrinolytic cascades modulator |
WO2009046194A2 (en) * | 2007-10-05 | 2009-04-09 | The Board Of Trustees Of The University Of Illinois | Fibrin sealant |
US20100297257A1 (en) | 2007-11-09 | 2010-11-25 | National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs) | Anticoagulant antagonist and hemophillia procoagulant |
US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
SE1050124A1 (sv) * | 2010-02-08 | 2011-08-09 | Linkoping Biocontrols Ab | Stabil lösning |
WO2011159820A1 (en) * | 2010-06-15 | 2011-12-22 | Bayer Healthcare Llc | Device |
WO2012109743A1 (en) * | 2011-02-18 | 2012-08-23 | Precision Biologic Inc. | Methods and compositions relating to coagulation assays |
CN107748267B (zh) * | 2017-10-13 | 2019-02-26 | 山东艾科达生物科技有限公司 | 一种测定活化部分凝血活酶时间(aptt)的试剂盒 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3307392A (en) * | 1964-05-04 | 1967-03-07 | Research Corp | Automatic prothrombin timer apparatus and method |
US3458287A (en) * | 1965-04-29 | 1969-07-29 | Medical Laboratory Automation | Method and means of determining endpoint times in blood clotting tests |
US3658480A (en) * | 1970-04-13 | 1972-04-25 | Bio Data Corp | Coagulation timing apparatus, and method |
US4047890A (en) * | 1973-11-01 | 1977-09-13 | Bio/Data Corporation | Method and apparatus for determining deficiencies in enzymatic reactors particularly clotting factor levels in blood plasmas |
US4289498A (en) * | 1979-01-08 | 1981-09-15 | Ortho Diagnostics, Inc. | One-stage prothrombin assay and compositions useful therein |
US4766083A (en) * | 1982-04-04 | 1988-08-23 | Wako Pure Chemical Industries, Ltd. | Method for the photometric determination of biological agglutination |
DE3407280A1 (de) * | 1984-02-28 | 1985-09-19 | Gödecke AG, 1000 Berlin | Testsatz zur bestimmung der aktivierten partiellen thromboplastinzeit (ptt) mit erhoehter heparinempfindlichkeit |
DE3413311A1 (de) * | 1984-04-09 | 1985-10-17 | Behringwerke Ag, 3550 Marburg | Reagenz zur bestimmung der thromboplastinzeit |
GB8426004D0 (en) * | 1984-10-15 | 1984-11-21 | Ortho Diagnostic Systems Inc | Coagulation monitoring |
IT1197891B (it) * | 1986-10-17 | 1988-12-21 | Instrumentation Lab Spa | Metodo per la determinazione dell'attivita' biologica della proteina c nel plasma umano, e relativi reagenti |
-
1989
- 1989-12-19 US US07/452,802 patent/US5169786A/en not_active Expired - Lifetime
-
1990
- 1990-12-11 GR GR900100852A patent/GR1001222B/el not_active IP Right Cessation
- 1990-12-18 DK DK90313862.6T patent/DK0434377T3/da active
- 1990-12-18 EP EP90313862A patent/EP0434377B1/de not_active Expired - Lifetime
- 1990-12-18 DE DE69021849T patent/DE69021849T2/de not_active Expired - Lifetime
- 1990-12-18 CA CA002032561A patent/CA2032561C/en not_active Expired - Lifetime
- 1990-12-18 ES ES90313862T patent/ES2088992T3/es not_active Expired - Lifetime
- 1990-12-18 AT AT90313862T patent/ATE126894T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GR900100852A (en) | 1992-05-12 |
EP0434377B1 (de) | 1995-08-23 |
DE69021849D1 (de) | 1995-09-28 |
CA2032561C (en) | 2000-04-18 |
DE69021849T2 (de) | 1995-12-21 |
ATE126894T1 (de) | 1995-09-15 |
EP0434377A1 (de) | 1991-06-26 |
CA2032561A1 (en) | 1991-06-20 |
DK0434377T3 (da) | 1995-09-25 |
US5169786A (en) | 1992-12-08 |
GR1001222B (el) | 1993-06-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2088992T3 (es) | Metodo para determinar los niveles de factores de coagulacion intrinsecos y extrinsecos y proteina c. | |
DE69832628D1 (de) | Rekombinant-kaninchengewebefaktor basiertes prothrombinzeitreagenz | |
ES547898A0 (es) | Un metodo para determinar la presencia de un componente de coagulacion | |
DE69018910D1 (de) | Verfahren zur Bestimmung des endogenen Thrombinpotentials von Plasma und Blut und Reagenziensatz zur Verwendung in besagtem Verfahren. | |
DE59813326D1 (de) | Verfahren zur Bestimmung des antikoagulatorischen Potentials einer Probe und Verfahren zur Bestimmung der Glykosilierung von Thrombomodulin | |
ES542020A0 (es) | Procedimiento para la determincion fotometrica del tiempo de tromboplastina. | |
DE69801210T2 (de) | Verbesserte in vitro Verfahren, Testkits und Reagenzien zum Screening von Blutgerinnungsfehlern | |
US5780255A (en) | Protein C pathway screening test | |
DE59708506D1 (de) | Verfahren zum durchführen von bluttests | |
DK173090A (da) | Forbedrede ekstraktionsmetoder til fremstilling af thromboplastinreagenser | |
AU1538202A (en) | A reagent and kit for determining global coagulability and hemostatic potential | |
ATE16944T1 (de) | Reagens zur optischen bestimmung des blutgerinnungsverhaltens. | |
Calatzis et al. | The prothrombinase-induced clotting test: A new technique for the monitoring of anticoagulants | |
DE59309374D1 (de) | Reagens zur Bestimmung der aktivierten partiellen Thromboplastinzeit (aPTT) | |
FI932194A0 (fi) | Anvaendningen av protrombinfragment | |
ATE191278T1 (de) | Tetrahydroxychinon als eine aktivatorkomponente für den aktivierten partiellen thromboplastinzeit-test der blutgerinnung und als anzeiger von blutgerinnungsstörungen | |
ATE265685T1 (de) | Verbesserter blutgerinnungstest | |
Clatzis et al. | The prothrombinase-induced clotting test: a new technique for the monitoring of anticoagulants | |
ATE200710T1 (de) | Verfahren zur diagnose von blutgerinnungsstörungen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 434377 Country of ref document: ES |
|
FG2A | Definitive protection |
Ref document number: 434377 Country of ref document: ES |