ES2088588T3 - Nuevos derivados triciclicos de tiazol y oxazol con efecto antivirico. - Google Patents

Nuevos derivados triciclicos de tiazol y oxazol con efecto antivirico.

Info

Publication number
ES2088588T3
ES2088588T3 ES92918311T ES92918311T ES2088588T3 ES 2088588 T3 ES2088588 T3 ES 2088588T3 ES 92918311 T ES92918311 T ES 92918311T ES 92918311 T ES92918311 T ES 92918311T ES 2088588 T3 ES2088588 T3 ES 2088588T3
Authority
ES
Spain
Prior art keywords
pct
atoms
ring
substituted
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92918311T
Other languages
English (en)
Inventor
Harald Zilch
Herbert Leinert
Alfred Mertens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2088588T3 publication Critical patent/ES2088588T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A DERIVADOS TIAZOLO ,3 LA CUAL HET ES UN ANILLO HETEROCICLICO CON 3-7 ATOMOS DE ANILLO QUE PUEDEN SER SUSTITUIDOS POR 1,2 O 3 RESTOS R1, PUDIENDO SER IGUALES O DIFERENTES; Y ES OXIGENO O ATOMO DE AZUFRE, O GRUPOS SO O SO2; X PUEDE SER UN ATOMO DE OXIGENO O AZUFRE; R SIGNIFICA UN RESTO ALIFATICO CON 1-9 ATOMOS DE C QUE PUEDE SER SUSTITUIDO POR FENILO, O POR UN ANILLO FENILO, O POR UN ANILLO CARBOCICLICO CON 7-15 ATOMOS DE C O POR UN SISTEMA DE ANILLO HETEROCICLICO CON 5 A 6 ATOMOS DE ANILLO CADA UNO. LOS MENCIONADOS ANILLOS FENILO, ANILLOS CARBOCICLICOS O SISTEMA DE ANILLO HETEROCICLICO PUEDEN SER SUSTITUIDOS SI ES NECESARIO UNA O VARIAS VECES Y LOS RESTOS R1 CO. SE DESCRIBEN TAMBIEN SUS TAUTOMEROS, ENANTIOMEROS, DIASTEREOMEROS Y SALES TOLERABLES FISIOLOGICAMENTE, ASI COMO LOS MEDICAMENTOS QUE CONTIENEN LOS COMPUESTOS DE LA FORMULA (I).
ES92918311T 1991-09-07 1992-09-02 Nuevos derivados triciclicos de tiazol y oxazol con efecto antivirico. Expired - Lifetime ES2088588T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4129779A DE4129779A1 (de) 1991-09-07 1991-09-07 Neue tricyclische thiazol- und oxazol-derivate und diese enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES2088588T3 true ES2088588T3 (es) 1996-08-16

Family

ID=6440096

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92918311T Expired - Lifetime ES2088588T3 (es) 1991-09-07 1992-09-02 Nuevos derivados triciclicos de tiazol y oxazol con efecto antivirico.

Country Status (9)

Country Link
US (1) US5512564A (es)
EP (1) EP0602097B1 (es)
JP (1) JPH06510295A (es)
AT (1) ATE137240T1 (es)
AU (1) AU2482892A (es)
CA (1) CA2117062A1 (es)
DE (2) DE4129779A1 (es)
ES (1) ES2088588T3 (es)
WO (1) WO1993005047A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4311782A1 (de) * 1993-04-09 1994-10-13 Boehringer Mannheim Gmbh Indazol-Derivate und diese enthaltende Arzneimittel
FR2757059B1 (fr) * 1996-12-12 1999-01-29 Rhone Poulenc Rorer Sa Nouvelle application therapeutique des derives du pyrrole
EP1102755B1 (en) 1998-08-07 2006-01-04 Chiron Corporation Substituted isoxazole derivatives as estrogen receptor modulators
EP1132389A1 (en) * 2000-03-06 2001-09-12 Vernalis Research Limited New aza-indolyl derivatives for the treatment of obesity
FR2814700B1 (fr) 2000-10-03 2003-01-10 Mavic Sa Corps de roue libre d'un moyeu arriere de bicyclette et moyeu equipe d'un tel corps
WO2002066479A1 (fr) * 2001-02-23 2002-08-29 Banyu Pharmaceutical Co.,Ltd. Derives de l'isoindole
DE602004031258D1 (de) * 2003-12-24 2011-03-10 Biota Scient Management Polycyclische mittel zur behandlung von infektione
TWI423972B (zh) * 2006-09-28 2014-01-21 Biota Scient Management 治療呼吸系融合細胞病毒感染之多環劑
TWI508968B (zh) 2010-02-08 2015-11-21 Biota Scient Management 用於治療呼吸道融合性病毒感染的化合物
US8796303B2 (en) 2010-11-26 2014-08-05 Biota Scientific Management Pty Ltd. Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE564592A (es) * 1957-02-11
US3334113A (en) * 1963-12-18 1967-08-01 Sandoz Ag 9b-phenyl-1, 2, 3, 9b-tetrahydro-5h-imidazo[2,1-a]isoindol-5-ones
CH433321A (de) * 1964-02-11 1967-04-15 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
US3336306A (en) * 1965-10-22 1967-08-15 American Home Prod Oxazoloisoindolones and related compounds
DE4035809A1 (de) * 1990-11-10 1992-05-14 Boehringer Mannheim Gmbh Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel
IL100119A0 (en) * 1990-11-27 1992-08-18 Boehringer Mannheim Gmbh Optically-active thiazoloisoindolinone derivatives with antiviral action
DE4103177A1 (de) * 1991-02-02 1992-08-06 Boehringer Mannheim Gmbh Thiazolo-(2,3-a)isoindol-derivate und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0602097A1 (de) 1994-06-22
JPH06510295A (ja) 1994-11-17
DE59206130D1 (de) 1996-05-30
DE4129779A1 (de) 1993-03-11
WO1993005047A1 (de) 1993-03-18
EP0602097B1 (de) 1996-04-24
ATE137240T1 (de) 1996-05-15
US5512564A (en) 1996-04-30
AU2482892A (en) 1993-04-05
CA2117062A1 (en) 1993-03-18

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