ES2084753T3 - Niclosamida en locion topica. - Google Patents

Niclosamida en locion topica.

Info

Publication number
ES2084753T3
ES2084753T3 ES91119316T ES91119316T ES2084753T3 ES 2084753 T3 ES2084753 T3 ES 2084753T3 ES 91119316 T ES91119316 T ES 91119316T ES 91119316 T ES91119316 T ES 91119316T ES 2084753 T3 ES2084753 T3 ES 2084753T3
Authority
ES
Spain
Prior art keywords
weight
niclosamide
percent
formulation
topical lotion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91119316T
Other languages
English (en)
Inventor
John I E Day
Rao E Ramineni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of ES2084753T3 publication Critical patent/ES2084753T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/15Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA INVENCION PRESENTA UNA FORMULACION TOPICA ANTIPENETRANTE DE NICLOSAMIDA. LA FORMULACION PREFERIDA CONTIENE ALREDEDOR DE UNO POR CIENTO EN PESO DE NICLOSAMIDA, 40 A 55 POR CIENTO EN PESO DE GLICOL PROPILENO Y UNO 20 A 30 POR CIENTO EN PESO DE ETANOL AL 95%, 20 A 25% EN PESO DE GLICOL POLIETILENO 400 Y DE APROXIMADAMENTE 0,1 A 10% EN PESO DE AGUA. ESTA FORMULACION CONSTITUYE UNA BARRERA EFECTIVA SOBRE LA PIEL, IMPIDIENDO LA PENETRACION DE SCHISTOSOMA CERCACIAE, EL ESTADO INFECCIOSO DEL CICLO DE VIDA DEL PARASITO.
ES91119316T 1990-11-26 1991-11-13 Niclosamida en locion topica. Expired - Lifetime ES2084753T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61777890A 1990-11-26 1990-11-26
US76081991A 1991-09-17 1991-09-17

Publications (1)

Publication Number Publication Date
ES2084753T3 true ES2084753T3 (es) 1996-05-16

Family

ID=27088095

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91119316T Expired - Lifetime ES2084753T3 (es) 1990-11-26 1991-11-13 Niclosamida en locion topica.

Country Status (8)

Country Link
EP (1) EP0487973B1 (es)
JP (1) JPH04266826A (es)
KR (1) KR920009388A (es)
AT (1) ATE135913T1 (es)
DE (1) DE69118327T2 (es)
DK (1) DK0487973T3 (es)
ES (1) ES2084753T3 (es)
GR (1) GR3019989T3 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2293683A1 (en) * 1997-06-11 1998-12-17 Bayer Aktiengesellschaft Anthelmintic compositions
ATE432072T1 (de) 2002-03-12 2009-06-15 Galderma Res & Dev Verwendung von adapalen zur behandlung dermatologischer erkrankungen
CN1985813B (zh) * 2006-12-07 2010-10-06 江苏省血吸虫病防治研究所 一种耕牛血吸虫病防护剂-氯硝柳胺乙醇胺盐喷雾剂及其制备方法
GB0711957D0 (en) * 2007-06-21 2007-08-01 Syntopix Ltd Formulations
CN102599158B (zh) * 2011-12-20 2013-10-23 中国计量学院 聚乙二醇-氯硝柳胺复合杀螺剂
CN103674954B (zh) * 2013-12-13 2015-12-02 江苏省血吸虫病防治研究所 一种用于检测日本血吸虫感染性水体的装置及检测方法
MX2017003251A (es) 2014-09-12 2017-12-20 Antibiotx Aps Uso antibacteriano de salicilanilidas halogenadas.
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
GB201604484D0 (en) * 2016-03-16 2016-04-27 Antibiotx Aps And Københavns Uni University Of Copenhagen Topical antibacterial compositions
GB201713653D0 (en) * 2017-08-24 2017-10-11 Antibiotx As Dosage regimen
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide
WO2021168328A1 (en) * 2020-02-21 2021-08-26 Yourchoice Therapeutics, Inc. Niclosamide formulations for use as contraceptive
AU2022217102A1 (en) * 2021-02-04 2023-08-31 Niclosavir Limited Niclosamide compositions having improved bioavailability

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659738A (en) * 1985-02-15 1987-04-21 The United States Of America As Represented By The Secretary Of The Army Topical prophylaxis against schistosomal infections
NZ223200A (en) * 1988-01-15 1989-01-06 Ancare Distributors Anthelmintic compositions containing 2',5-dicloro-4'-nitrosalicylanilide and non aqueous carrier

Also Published As

Publication number Publication date
JPH04266826A (ja) 1992-09-22
EP0487973B1 (en) 1996-03-27
ATE135913T1 (de) 1996-04-15
EP0487973A1 (en) 1992-06-03
DE69118327D1 (de) 1996-05-02
KR920009388A (ko) 1992-06-25
GR3019989T3 (en) 1996-08-31
DK0487973T3 (da) 1996-07-29
DE69118327T2 (de) 1996-08-29

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