ES2080023A1 - Capsidas y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que contienen dichos productos recombinantes. - Google Patents

Capsidas y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que contienen dichos productos recombinantes.

Info

Publication number
ES2080023A1
ES2080023A1 ES09401493A ES9401493A ES2080023A1 ES 2080023 A1 ES2080023 A1 ES 2080023A1 ES 09401493 A ES09401493 A ES 09401493A ES 9401493 A ES9401493 A ES 9401493A ES 2080023 A1 ES2080023 A1 ES 2080023A1
Authority
ES
Spain
Prior art keywords
rhdv
proteins
recombinant
disease virus
diagnostic kits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09401493A
Other languages
English (en)
Other versions
ES2080023B1 (es
Inventor
Duran Juan Plana
Alvarez Jose Ignacio Casal
Sanchez Isabel Climent
Garcia Maria Jose Rodriguez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Farma SA
Original Assignee
Cyanamid Iberica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES09401493A priority Critical patent/ES2080023B1/es
Application filed by Cyanamid Iberica SA filed Critical Cyanamid Iberica SA
Priority to SI9530719T priority patent/SI0704528T1/xx
Priority to DK95304719T priority patent/DK0704528T3/da
Priority to DE69534242T priority patent/DE69534242T2/de
Priority to ES95304719T priority patent/ES2240968T3/es
Priority to AT95304719T priority patent/ATE296887T1/de
Priority to EP95304719A priority patent/EP0704528B1/en
Priority to PT95304719T priority patent/PT704528E/pt
Priority to CN951150588A priority patent/CN1217954C/zh
Publication of ES2080023A1 publication Critical patent/ES2080023A1/es
Application granted granted Critical
Publication of ES2080023B1 publication Critical patent/ES2080023B1/es
Priority to HK98115794A priority patent/HK1014547A1/xx
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/16011—Caliciviridae
    • C12N2770/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

CAPSIDAS Y PROTEINAS RECOMBINANTES DEL VIRUS DE LA ENFERMEDAD HEMORRAGICA DEL CONEJO (RHDV), KITS DE DIAGNOSTICO Y VACUNAS QUE CONTIENEN DICHOS PRODUCTOS RECOMBINANTES. SE HAN PRODUCIDO CAPSIDAS Y PROTEINAS RECOMBINANTES DEL VIRUS DE LA ENFERMEDAD HEMORRAGICA DEL CONEJO (RHDV), EN UN SISTEMA DE EXPRESION DE BACULOVIRUS RECOMBINANTES REPLICADOS EN UN CULTIVO DE CELULAS DE INSECTO. ESTAS CAPSIDAS Y PROTEINAS RECOMBINANTES SON INMUROGENICA Y ANTIGENICAMENTE ANALOGAS A LA PROTEINA VP60 NATIVA DEL RHDV, Y SON ADECUADAS PARA FORMULAR VACUNAS CAPACES DE PROTEGER EFICAZMENTE A LOS CONEJOS DEL RHDV ASI COMO PARA PREPARAR KITS DE DIAGNOSTICO ADECUADOS PARA DETECTAR TANTO LA PRESENCIA DE ANTICUERPOS QUE RECONOCEN AL RHDV COMO LA PRESENCIA DE RHDV EN UNA MUESTRA BIOLOGICA DE CONEJO. ESTA INVENCION TIENE INTERES EN VETERINARIA.
ES09401493A 1994-07-08 1994-07-08 Capsidas y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que contienen dichos productos recombinantes. Expired - Fee Related ES2080023B1 (es)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ES09401493A ES2080023B1 (es) 1994-07-08 1994-07-08 Capsidas y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que contienen dichos productos recombinantes.
PT95304719T PT704528E (pt) 1994-07-08 1995-07-05 Capsides e proteinas recombinantes do virus da doenca hemorragica dos coelhos ("rhdv"), estojos ("kits") de diagnostico e vacinas que as incluem
DE69534242T DE69534242T2 (de) 1994-07-08 1995-07-05 Hämorrhagie-Virus
ES95304719T ES2240968T3 (es) 1994-07-08 1995-07-05 Capsides y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que las contienen.
AT95304719T ATE296887T1 (de) 1994-07-08 1995-07-05 Hämorrhagie-virus aus kaninchen (rhdv), rekombinante hullen und dessen proteine, diagnosesätze und impfstoffe die sie enthalten
EP95304719A EP0704528B1 (en) 1994-07-08 1995-07-05 Rabbit hemorrhagic disease virus (RHDV) recombinant capsids and proteins, diagnostic kits and vaccines containing them
SI9530719T SI0704528T1 (en) 1994-07-08 1995-07-05 Rabbit hemorrhagic disease virus (RHDV) recombinant capsids and proteins, diagnostic kits and vaccines containing them
DK95304719T DK0704528T3 (da) 1994-07-08 1995-07-05 Hæmorrhagisk sygdomsvirus hos kaniner (RHDV), rekombinante capsider og proteiner, diagnostiske kits og vacciner indeholdende dem
CN951150588A CN1217954C (zh) 1994-07-08 1995-07-07 兔出血病病毒重组衣壳和蛋白质及含有它们的诊断药盒和疫苗
HK98115794A HK1014547A1 (en) 1994-07-08 1998-12-28 Rabbit hemorrhagic disease virus (rhdv) recombinant capsids and proteins, diagnostic kits and vaccines containing them.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09401493A ES2080023B1 (es) 1994-07-08 1994-07-08 Capsidas y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que contienen dichos productos recombinantes.

Publications (2)

Publication Number Publication Date
ES2080023A1 true ES2080023A1 (es) 1996-01-16
ES2080023B1 ES2080023B1 (es) 1996-08-16

Family

ID=8286840

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09401493A Expired - Fee Related ES2080023B1 (es) 1994-07-08 1994-07-08 Capsidas y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que contienen dichos productos recombinantes.
ES95304719T Expired - Lifetime ES2240968T3 (es) 1994-07-08 1995-07-05 Capsides y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que las contienen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES95304719T Expired - Lifetime ES2240968T3 (es) 1994-07-08 1995-07-05 Capsides y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que las contienen.

Country Status (9)

Country Link
EP (1) EP0704528B1 (es)
CN (1) CN1217954C (es)
AT (1) ATE296887T1 (es)
DE (1) DE69534242T2 (es)
DK (1) DK0704528T3 (es)
ES (2) ES2080023B1 (es)
HK (1) HK1014547A1 (es)
PT (1) PT704528E (es)
SI (1) SI0704528T1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113907046A (zh) * 2021-11-09 2022-01-11 福建省连江县刘氏兔业养殖场 一种含特异性转移因子的ty26种兔群的选育方法和相应兔品系的培育方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2080024B1 (es) * 1994-07-06 1996-08-16 Univ Oviedo Vacuna subunitaria recombinante contra la enfermedad hemorragica virica de los conejos.
CA2454920C (en) * 2001-07-26 2013-06-25 Otago Innovation Limited Antigenic compositions
PL205229B1 (pl) * 2005-07-08 2010-03-31 Panstwowy Inst Weterynaryjny P Sposób wytwarzania rekombinowanej szczepionki przeciwko krwotocznej chorobie królików, szczepionka oraz zastosowanie antygenu rekombinowanego białka do wytwarzania szczepionki
PL205228B1 (pl) * 2005-07-08 2010-03-31 Panstwowy Inst Weterynaryjny P Zestaw diagnostyczny do badania surowic zwierząt na obecność przeciwciał RHD oraz zestaw diagnostyczny do wykrywania wirusa RHD
CN103033622B (zh) * 2011-12-26 2015-03-25 武汉中博生物股份有限公司 猪圆环病毒2型elisa抗原检测试剂盒及其制备方法和其应用
CN104694481B (zh) * 2015-04-01 2017-07-07 中国农业科学院哈尔滨兽医研究所 杂交瘤细胞株McAb 1H2及兔出血症RHDVa型病毒单克隆抗体
CN105486861B (zh) * 2015-07-02 2017-07-11 山东省滨州畜牧兽医研究院 一种兔瘟病毒抗体快速检测卡及其制备方法
CN107164252B (zh) * 2016-03-08 2020-10-20 上海海利生物技术股份有限公司 一种rhdv的亚单位疫苗
CN115725511B (zh) * 2022-08-29 2024-02-09 四川农业大学 一种杂交瘤细胞株R2McAb2A1及其分泌的单克隆抗体和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991001332A1 (en) * 1989-07-21 1991-02-07 The Upjohn Company Feline calicivirus capsid protein and nucleotide sequence
ES2026827A6 (es) * 1991-03-26 1992-05-01 Ercros Sa Procedimiento para la produccion de una vacuna subunidad contra el parvovirus porcino.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2690838B1 (fr) * 1992-05-06 1996-07-12 Rhone Merieux Ensemble de vaccination contre la maladie hemorragique virale du lapin et vaccins conditionnes pour etre utilises dans cet ensemble.
ES2080024B1 (es) * 1994-07-06 1996-08-16 Univ Oviedo Vacuna subunitaria recombinante contra la enfermedad hemorragica virica de los conejos.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991001332A1 (en) * 1989-07-21 1991-02-07 The Upjohn Company Feline calicivirus capsid protein and nucleotide sequence
ES2026827A6 (es) * 1991-03-26 1992-05-01 Ercros Sa Procedimiento para la produccion de una vacuna subunidad contra el parvovirus porcino.

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BISHOP D.H.L. "Baculovirus expression vectors" Seminars in virology. 1992. Vol. 3, pßg. 253-264 *
LUCKOW, V.A. et al. "Trends in the development of baculovirus expression vectors" Biotechnology. Enero 1988. Vol. 6, pßg. 47-55 *
MEYERS G. et al. "Genomic and subgenomic RNAs of rabbit Hemorrhagic disease virus are both protein-linked and packaged into particles" Virology. 1991. Vol. 184, pßg. 677-686 *
MEYERS G. et al. "Rabbit hemorrhagic disease virus: Molecular Cloning and nucleotide sequencing of a calicivirus genome" Virology. 1991. Vol. 184, pßg. 664-676 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113907046A (zh) * 2021-11-09 2022-01-11 福建省连江县刘氏兔业养殖场 一种含特异性转移因子的ty26种兔群的选育方法和相应兔品系的培育方法

Also Published As

Publication number Publication date
ES2240968T3 (es) 2005-10-16
CN1134461A (zh) 1996-10-30
DK0704528T3 (da) 2005-07-04
EP0704528B1 (en) 2005-06-01
HK1014547A1 (en) 1999-09-30
EP0704528A3 (en) 1998-03-04
PT704528E (pt) 2005-09-30
DE69534242D1 (de) 2005-07-07
DE69534242T2 (de) 2006-05-11
ES2080023B1 (es) 1996-08-16
EP0704528A2 (en) 1996-04-03
CN1217954C (zh) 2005-09-07
SI0704528T1 (en) 2005-10-31
ATE296887T1 (de) 2005-06-15

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