ES2078434T3 - Hexahidrobenz(cd)indoles y procedimiento para su preparacion. - Google Patents

Hexahidrobenz(cd)indoles y procedimiento para su preparacion.

Info

Publication number
ES2078434T3
ES2078434T3 ES91301500T ES91301500T ES2078434T3 ES 2078434 T3 ES2078434 T3 ES 2078434T3 ES 91301500 T ES91301500 T ES 91301500T ES 91301500 T ES91301500 T ES 91301500T ES 2078434 T3 ES2078434 T3 ES 2078434T3
Authority
ES
Spain
Prior art keywords
indoles
preparation
hexahidrobenz
procedure
hexahydrobenz
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91301500T
Other languages
English (en)
Inventor
Thomas Joseph Kress
Marvin Robert Leanna
Michael John Martinelli
Barry Curtis Peterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2078434T3 publication Critical patent/ES2078434T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

NUEVOS INTERMEDIOS Y PROCESOS DE LO ANTERIOR, SUMINISTRAN UN METODO PARA DERIVAR 4-AMINO-1,2,2A,3,4,5-HEXAHIDROBENZ[CD]INDOLES, QUE SON A SU VEZ INTERMEDIOS COMO AGENTES UTILES CNS, DE LOS KORNFELD-WOODWARD KETONE Y COMPUESTOS SIMILARES. EMBODIMENTOS PREFERENTES SUMINISTRAN MEDIOS PARA LA PRODUCCION DE ENANTIOMERES SUSTANCIALMENTE PUROS DEL 4-AMINO-1,2,2A,3,4,5, -HEXAHIDROBENZ[CD]INDOLE.
ES91301500T 1990-02-26 1991-02-26 Hexahidrobenz(cd)indoles y procedimiento para su preparacion. Expired - Lifetime ES2078434T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48519490A 1990-02-26 1990-02-26

Publications (1)

Publication Number Publication Date
ES2078434T3 true ES2078434T3 (es) 1995-12-16

Family

ID=23927262

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91301500T Expired - Lifetime ES2078434T3 (es) 1990-02-26 1991-02-26 Hexahidrobenz(cd)indoles y procedimiento para su preparacion.

Country Status (13)

Country Link
EP (1) EP0444851B1 (es)
JP (1) JP2968070B2 (es)
KR (2) KR0171418B1 (es)
AT (1) ATE127454T1 (es)
CA (1) CA2037098C (es)
DE (1) DE69112670T2 (es)
DK (1) DK0444851T3 (es)
ES (1) ES2078434T3 (es)
GR (1) GR3017777T3 (es)
HU (1) HU215965B (es)
IE (1) IE68887B1 (es)
IL (2) IL97309A (es)
PH (1) PH31173A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
IL74222A (en) * 1984-02-06 1988-07-31 Lilly Co Eli 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
TW219933B (es) * 1990-02-26 1994-02-01 Lilly Co Eli
US5039820A (en) * 1990-02-26 1991-08-13 Eli Lilly And Company 4-amino-6-iodo-hexahydrobenz(cd)indoles
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
HU215965B (hu) 1999-03-29
HU63191D0 (en) 1991-09-30
DE69112670D1 (de) 1995-10-12
JPH04211653A (ja) 1992-08-03
CA2037098A1 (en) 1991-08-27
JP2968070B2 (ja) 1999-10-25
EP0444851B1 (en) 1995-09-06
IL97309A0 (en) 1992-05-25
DE69112670T2 (de) 1996-03-07
IL97309A (en) 1996-11-14
PH31173A (en) 1998-03-20
IE910624A1 (en) 1991-08-28
KR0176247B1 (ko) 1999-03-20
CA2037098C (en) 2006-04-18
HUT68729A (en) 1995-07-28
KR0171418B1 (ko) 1999-02-01
IE68887B1 (en) 1996-07-24
IL111027A0 (en) 1994-11-28
GR3017777T3 (en) 1996-01-31
IL111027A (en) 1996-05-14
KR910021404A (ko) 1991-12-20
EP0444851A3 (en) 1992-02-19
KR910021376A (ko) 1991-12-20
DK0444851T3 (da) 1995-10-23
EP0444851A2 (en) 1991-09-04
ATE127454T1 (de) 1995-09-15

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