ATE138911T1 - Hexahydro(cd>indole - Google Patents

Hexahydro(cd>indole

Info

Publication number
ATE138911T1
ATE138911T1 AT91301502T AT91301502T ATE138911T1 AT E138911 T1 ATE138911 T1 AT E138911T1 AT 91301502 T AT91301502 T AT 91301502T AT 91301502 T AT91301502 T AT 91301502T AT E138911 T1 ATE138911 T1 AT E138911T1
Authority
AT
Austria
Prior art keywords
hexahydro
indole
amino
indoles
useful
Prior art date
Application number
AT91301502T
Other languages
English (en)
Inventor
Thomas Joseph Kress
James Patrick Wepsiec
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE138911T1 publication Critical patent/ATE138911T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT91301502T 1990-02-26 1991-02-26 Hexahydro(cd>indole ATE138911T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/485,193 US5039820A (en) 1990-02-26 1990-02-26 4-amino-6-iodo-hexahydrobenz(cd)indoles

Publications (1)

Publication Number Publication Date
ATE138911T1 true ATE138911T1 (de) 1996-06-15

Family

ID=23927258

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91301502T ATE138911T1 (de) 1990-02-26 1991-02-26 Hexahydro(cd>indole

Country Status (13)

Country Link
US (1) US5039820A (de)
EP (1) EP0444853B1 (de)
JP (1) JP3011465B2 (de)
KR (1) KR0177166B1 (de)
AT (1) ATE138911T1 (de)
CA (1) CA2037116C (de)
DE (1) DE69119933T2 (de)
DK (1) DK0444853T3 (de)
ES (1) ES2088460T3 (de)
GR (1) GR3020474T3 (de)
HU (1) HU219590B (de)
IE (1) IE73230B1 (de)
IL (1) IL97307A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97309A (en) * 1990-02-26 1996-11-14 Lilly Co Eli Intermediates for hexahydrobenz] [DC indoles and a process for making their pure enantiomers
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
US5229410A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5347013A (en) * 1991-03-28 1994-09-13 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5643934A (en) * 1991-03-28 1997-07-01 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz [CD]indoles
US5385928A (en) * 1994-05-18 1995-01-31 Eli Lilly And Company Tetrahydrobenz [CD] indazoles, compositions and use
US5498727A (en) * 1994-07-19 1996-03-12 Agouron Pharmaceuticals, Inc. Preparation of benzindole compounds from naphthalene compounds
ZA9610853B (en) * 1995-12-29 1998-04-06 Smithkline Beecham Corp Processes and intermediates for preparing pharmaceuticals.
TW430660B (en) * 1996-05-30 2001-04-21 Mochida Pharm Co Ltd Novel benzindole derivatives for neuron cell protection, processes for production, and the pharmaceutical compounds containing them
KR20010035079A (ko) * 2000-12-16 2001-05-07 홍정원 바이오 보드 및 이 바이오 보드를 이용한 물품 보관함

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74222A (en) * 1984-02-06 1988-07-31 Lilly Co Eli 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
DE3525564A1 (de) * 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists

Also Published As

Publication number Publication date
IL97307A0 (en) 1992-05-25
HU219590B (hu) 2001-05-28
JP3011465B2 (ja) 2000-02-21
DE69119933T2 (de) 1996-10-31
IL97307A (en) 1995-06-29
US5039820A (en) 1991-08-13
IE910623A1 (en) 1991-08-28
DE69119933D1 (de) 1996-07-11
IE73230B1 (en) 1997-05-21
ES2088460T3 (es) 1996-08-16
CA2037116C (en) 2003-10-28
EP0444853A2 (de) 1991-09-04
JPH04211652A (ja) 1992-08-03
KR0177166B1 (ko) 1999-03-20
EP0444853A3 (en) 1992-02-19
HUT56540A (en) 1991-09-30
GR3020474T3 (en) 1996-10-31
KR910021374A (ko) 1991-12-20
EP0444853B1 (de) 1996-06-05
CA2037116A1 (en) 1991-08-27
DK0444853T3 (da) 1996-06-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee