ES2074563T3 - Procedimiento de preparacion de compuestos y metodo para el tratamiento de la septicemia y/o el choque septico. - Google Patents
Procedimiento de preparacion de compuestos y metodo para el tratamiento de la septicemia y/o el choque septico.Info
- Publication number
- ES2074563T3 ES2074563T3 ES90902432T ES90902432T ES2074563T3 ES 2074563 T3 ES2074563 T3 ES 2074563T3 ES 90902432 T ES90902432 T ES 90902432T ES 90902432 T ES90902432 T ES 90902432T ES 2074563 T3 ES2074563 T3 ES 2074563T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- gram
- septic shock
- negative bacteria
- septicemia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
COMPOSICIONES FARMACEUTICAS USADAS PARA EL TRATAMIENTO O PROFILAXIS DE ATAQUES DE BACTERIAS GRAM-NEGATIVAS O DE CHOQUES SEPTICOS, QUE CONTIENEN UNA CANTIDAD SUFICIENTE ANTIBACTERIANA DE INMUNOGLOBULINAS POLICLONICAS CONTRA BACTERIAS GRAM-NEGATIVAS Y UNA CANTIDAD EFECTIVA DE PROTEINA C PARA DISOLVER COAGULOS EN LA SANGRE. LAS COMPOSICIONES PUEDEN CONTENER ADEMAS UNO O MAS COFACTORES DE PROTEINA C Y ANTICUERPOS MONOCLONICOS CONTRA ENDOTOXINAS DE BACTERIAS GRAM-NEGATIVAS. UN METODO PARA EL TRATAMIENTO O PROFILAXIS DE INFECCIONES BACTERIANAS GRAM-NEGATIVAS, O DE CHOQUES SEPTICOS, COMPRENDE LA ADMINISTRACION, JUNTOS O POR SEPARADO, DE UNA CANTIDAD ANTIBACTERIANA EFECTIVA DE INMUNOGLOBULINAS POLICLONICAS CONTRA BACTERIAS GRAM-NEGATIVAS Y DE UNA CANTIDAD EFECTIVA DE PROTEINA C PARA DISOLVER COAGULOS SANGUINEOS. EL METODO PUEDE INCLUIR OPCIONALMENTE ADMINISTRAR UNO O MAS COFACTORES DE PROTEINA C Y ANTICUERPOS MONOCLONICOS CONTRA ENDOTOXINAS DE BACTERIAS GRAM-NEGATIVAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/300,836 US5093117A (en) | 1989-01-24 | 1989-01-24 | Compositions and method for the treatment or prophylaxis of sepsis or septic shock |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2074563T3 true ES2074563T3 (es) | 1995-09-16 |
Family
ID=23160797
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90902432T Expired - Lifetime ES2074563T3 (es) | 1989-01-24 | 1990-01-17 | Procedimiento de preparacion de compuestos y metodo para el tratamiento de la septicemia y/o el choque septico. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5093117A (es) |
EP (1) | EP0406398B1 (es) |
JP (1) | JP3038006B2 (es) |
CA (1) | CA1339990C (es) |
DE (1) | DE69019072T2 (es) |
DK (1) | DK0406398T3 (es) |
ES (1) | ES2074563T3 (es) |
WO (1) | WO1990008556A1 (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5571786A (en) * | 1990-08-16 | 1996-11-05 | Immuno Aktiengesellschaft | Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation |
AT402260B (de) * | 1990-08-16 | 1997-03-25 | Immuno Ag | Protein c-hältige pharmazeutische präparation |
AT397615B (de) * | 1991-05-14 | 1994-05-25 | Immuno Ag | Arzneimittel enthaltend protein c |
WO1994002172A1 (en) | 1992-07-24 | 1994-02-03 | Oklahoma Medical Research Foundation | Blockade of protein c activation reduces microvascular surgical blood loss |
US7060484B1 (en) | 1993-11-12 | 2006-06-13 | Gilead Sciences, Inc. | Polypeptides and coagulation therapy |
DE69434332T2 (de) * | 1993-11-12 | 2006-02-02 | Gilead Sciences, Inc., Foster City | Thrombin mutanten |
US5580856A (en) * | 1994-07-15 | 1996-12-03 | Prestrelski; Steven J. | Formulation of a reconstituted protein, and method and kit for the production thereof |
US20060127387A1 (en) * | 1997-04-22 | 2006-06-15 | Zikria Bashir A | Compositions based on polysaccharides and protein C and methods of using the same for preventing and treating sepsis and other conditions |
US6159468A (en) * | 1997-04-28 | 2000-12-12 | Eli Lilly And Company | Activated protein C formulations |
US6630137B1 (en) | 1997-04-28 | 2003-10-07 | Eli Lilly And Company | Activated protein C formulations |
DE19726248C2 (de) * | 1997-06-20 | 2000-03-02 | Mucos Pharma Gmbh & Co | Verwendung proteolytischer Enzyme und Rutosid zur Behandlung von septischem Schock |
US6953568B1 (en) | 1998-08-25 | 2005-10-11 | Oklahoma Medical Research Foundation | Targeting of molecules to large vessel endothelium using EPCR |
WO2000023101A1 (en) * | 1998-10-22 | 2000-04-27 | Eli Lilly And Company | Methods for treating sepsis |
JP2002542148A (ja) * | 1998-12-21 | 2002-12-10 | イーライ・リリー・アンド・カンパニー | 敗血症の処置のための組み合わせ療法 |
US6679870B1 (en) | 1999-07-23 | 2004-01-20 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
US6685694B2 (en) | 1999-07-23 | 2004-02-03 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
US7592304B2 (en) * | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
US7632803B2 (en) | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
US20030158111A1 (en) * | 1999-10-01 | 2003-08-21 | David Bar-Or | Methods and products for oral care |
US7204981B2 (en) * | 2000-03-28 | 2007-04-17 | Eli Lilly And Company | Methods of treating diseases with activated protein C |
WO2001089558A2 (en) | 2000-05-24 | 2001-11-29 | Eli Lilly And Company | Formulations and use of activated protein c and protein c zymogen for treating hypercoagulable states |
CA2437099A1 (en) * | 2001-01-30 | 2002-10-10 | The Lauridsen Group, Incorporated | Methods and compositions for treatment of immune dysfunction disorders |
EP1357943A2 (en) * | 2001-01-30 | 2003-11-05 | The Lauridsen Group Incorporated | Methods and compositions for modulating the immune system of animals |
US20030190314A1 (en) * | 2001-01-30 | 2003-10-09 | The Lauridsen Group | Methods and compositions of treatment for modulating the immune system of animals |
WO2003007686A2 (en) * | 2001-07-19 | 2003-01-30 | Dmi Biosciences, Inc. | Use of copper chelators to inhibit the inactivation of protein c |
AU2003213146A1 (en) * | 2002-03-08 | 2003-09-22 | Eli Lilly And Company | Activated protein c formulations |
ES2387275T3 (es) | 2003-05-15 | 2012-09-19 | Genentech, Inc. | Métodos y composiciones para la prevención y el tratamiento de la sepsis |
AU2005313971B2 (en) * | 2004-12-08 | 2011-10-13 | Immunomedics, Inc. | Methods and compositions for immunotherapy and detection of inflammatory and immune-dysregulatory disease, infectious disease, pathologic angiogenesis and cancer |
US8834862B2 (en) * | 2005-04-19 | 2014-09-16 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent |
ITFI20070063A1 (it) * | 2007-03-15 | 2008-09-16 | Kedrion Spa | Concentrato di proteina c contenente proteina s, sua preparazione ed uso. |
US20150150954A1 (en) | 2012-07-04 | 2015-06-04 | The University Of Sydney | Treatment of inflammatory skin disorders |
WO2015157791A1 (en) | 2014-04-16 | 2015-10-22 | The University Of Sydney | Treatment of abnormal cutaneous scarring |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4587121A (en) * | 1983-06-14 | 1986-05-06 | Miles Laboratories, Inc. | High titer Pseudomonas immune serum globulin |
GB8319538D0 (en) * | 1983-07-20 | 1983-08-24 | Beecham Group Plc | Compounds |
US5179018A (en) * | 1983-10-14 | 1993-01-12 | Centocor, Inc. | Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria |
DE3516119A1 (de) * | 1985-05-04 | 1986-11-06 | Biotest Pharma GmbH, 6000 Frankfurt | Polyvalentes hyperimmunglobulin-praeparat |
US5258288A (en) * | 1986-07-25 | 1993-11-02 | Genzyme Corporation | Vector containing DNA encoding mature human protein S |
-
1989
- 1989-01-24 US US07/300,836 patent/US5093117A/en not_active Expired - Lifetime
- 1989-09-29 CA CA000615182A patent/CA1339990C/en not_active Expired - Fee Related
-
1990
- 1990-01-17 ES ES90902432T patent/ES2074563T3/es not_active Expired - Lifetime
- 1990-01-17 EP EP90902432A patent/EP0406398B1/en not_active Expired - Lifetime
- 1990-01-17 DE DE69019072T patent/DE69019072T2/de not_active Expired - Fee Related
- 1990-01-17 DK DK90902432.5T patent/DK0406398T3/da active
- 1990-01-17 WO PCT/US1990/000215 patent/WO1990008556A1/en active IP Right Grant
- 1990-01-17 JP JP02502465A patent/JP3038006B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0406398A1 (en) | 1991-01-09 |
US5093117A (en) | 1992-03-03 |
CA1339990C (en) | 1998-08-11 |
JP3038006B2 (ja) | 2000-05-08 |
WO1990008556A1 (en) | 1990-08-09 |
JPH03503536A (ja) | 1991-08-08 |
EP0406398B1 (en) | 1995-05-03 |
DE69019072D1 (de) | 1995-06-08 |
EP0406398A4 (en) | 1991-07-03 |
DK0406398T3 (da) | 1995-07-17 |
DE69019072T2 (de) | 1995-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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