ES2061873T3 - Enriquecimiento y concentracion de proteinas por ultrafiltracion. - Google Patents

Enriquecimiento y concentracion de proteinas por ultrafiltracion.

Info

Publication number
ES2061873T3
ES2061873T3 ES89118796T ES89118796T ES2061873T3 ES 2061873 T3 ES2061873 T3 ES 2061873T3 ES 89118796 T ES89118796 T ES 89118796T ES 89118796 T ES89118796 T ES 89118796T ES 2061873 T3 ES2061873 T3 ES 2061873T3
Authority
ES
Spain
Prior art keywords
ultrafiltration
enrichment
concentration
proteins
whey
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89118796T
Other languages
English (en)
Inventor
Christopher Thurman Cordle
Ronald Lewis Thomas
Larry Grant Criswell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2061873T3 publication Critical patent/ES2061873T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/14Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1425Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of whey, e.g. treatment of the UF permeate

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE PRESENTA UN PROCESO DE ULTRAFILTRADO PARA EL ENRIQUECIMIENTO Y CONCENTRACION DE PROTEINAS SELECCIONADAS DE ENTRE LAS PROTEINAS QUE CONTIENEN FLUIDOS. DE FORMA ILUSTRATIVA, IGG SE CONCENTRA A PARTIR DE SUERO POR MEDIO DE MULTIPLES PASOS DE ULTRA FILTRACION, USANDO UNA MEMBRANA DE ULTRA FILTRACION DE OXIDO METALICO, QUE SE CARACTERIZAN POR LOS DIFERENTES PH''S.
ES89118796T 1988-10-12 1989-10-10 Enriquecimiento y concentracion de proteinas por ultrafiltracion. Expired - Lifetime ES2061873T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/256,813 US4897465A (en) 1988-10-12 1988-10-12 Enrichment and concentration of proteins by ultrafiltration

Publications (1)

Publication Number Publication Date
ES2061873T3 true ES2061873T3 (es) 1994-12-16

Family

ID=22973692

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89118796T Expired - Lifetime ES2061873T3 (es) 1988-10-12 1989-10-10 Enriquecimiento y concentracion de proteinas por ultrafiltracion.

Country Status (13)

Country Link
US (1) US4897465A (es)
EP (1) EP0363896B1 (es)
JP (1) JPH02218691A (es)
KR (1) KR900005998A (es)
AT (1) ATE109792T1 (es)
AU (1) AU624633B2 (es)
CA (1) CA1330050C (es)
DE (1) DE68917407T2 (es)
ES (1) ES2061873T3 (es)
IE (1) IE64919B1 (es)
IL (1) IL91781A (es)
MX (1) MX163729B (es)
NZ (1) NZ230993A (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729031D0 (en) * 1987-12-11 1988-01-27 Express Foods Group Ltd Isolation of immunoglobulin rich fraction from whey
US5030720A (en) * 1988-09-01 1991-07-09 Merck & Co., Inc. Pres2+S hepatitis B vaccine derived from plasma
US5130237A (en) * 1989-06-19 1992-07-14 Clemson University Substrate conversion with an enzyme immobilized on an ultrafiltration membrane
DE4026365A1 (de) * 1990-08-21 1992-02-27 Biotest Pharma Gmbh Sterilfiltrierte kolostralmilch
US5270450A (en) * 1991-02-28 1993-12-14 Abbott Laboratories Soy protein isolates
IE914558A1 (en) * 1991-02-28 1992-09-09 Abbott Lab Isolation of proteins by ultrafiltration
CH687055A5 (de) * 1993-12-03 1996-09-13 Bucher Guyer Ag Masch Verfahren und Vorrichtung zum Eindicken von Fest/Fluessig-Gemischen mittels Membrantechnologie.
US5310877A (en) * 1993-04-08 1994-05-10 E. I. Du Pont De Nemours And Company Method for separating serum albumin and gamma globulin
US5344565A (en) * 1993-07-26 1994-09-06 Pall Corporation Method of treating a clogged porous medium
NL9301653A (nl) * 1993-09-24 1995-04-18 X Flow Bv Werkwijze voor het verwijderen van troebelheid veroorzakende bestanddelen uit een vloeistof met behulp van microfiltratie.
US5468844A (en) * 1994-01-07 1995-11-21 Protose Technologies Inc. Process for the membrane-filtering of protein solutions
US5707678A (en) * 1995-04-12 1998-01-13 Galagen Inc. Method for microfiltration of milk or colostral whey
US5654025A (en) * 1995-10-30 1997-08-05 Raghunath; Bala Ultrafiltration of cooled milk
US6268487B1 (en) 1996-05-13 2001-07-31 Genzyme Transgenics Corporation Purification of biologically active peptides from milk
CA2197515A1 (en) * 1996-07-15 1998-01-16 Reyad Mahmoud Methods of treating milk products
CA2264630C (en) 1996-09-06 2006-12-12 Pall Corporation Shear separation method and system
WO1998054195A1 (en) 1997-05-30 1998-12-03 Bion, Inc. Large-scale isolation and purification of hif
TW409035B (en) 1997-06-04 2000-10-21 Gist Brocades Bv Starch-based enzyme granulates
US6068993A (en) * 1997-07-02 2000-05-30 Biobras Sa Vector for expression of heterologous protein and methods for extracting recombinant protein and for purifying isolated recombinant insulin
EP1071744B1 (en) * 1998-04-14 2003-06-25 Dsm N.V. Membrane filtration
US6313273B1 (en) * 1999-08-25 2001-11-06 Abbott Laboratories Soy proteins and methods for their production
CA2408124A1 (en) * 2000-05-05 2001-11-15 Harry M. Meade Transgenically produced decorin
US20040219281A1 (en) * 2000-11-21 2004-11-04 Cargill, Incorporated Modified oilseed material
US7429399B2 (en) * 2001-06-18 2008-09-30 Solae, Llc Modified oilseed material
US6630195B1 (en) 2000-11-21 2003-10-07 Cargill, Incorporated Process for producing oilseed protein products
AU2001297915B2 (en) 2000-11-21 2006-06-15 Cargill, Inc Modified oilseed material
US6875459B2 (en) * 2001-09-10 2005-04-05 Henry B. Kopf Method and apparatus for separation of milk, colostrum, and whey
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
MY150740A (en) * 2002-10-24 2014-02-28 Abbvie Biotechnology Ltd Low dose methods for treating disorders in which tnf? activity is detrimental
WO2004050847A2 (en) * 2002-11-27 2004-06-17 Gtc Biotherapeutics, Inc. Modified antibodies stably produced in milk and methods of producing same
US7354616B2 (en) * 2003-11-25 2008-04-08 Solae, Llc Modified oilseed material with a high gel strength
US7282571B2 (en) * 2004-02-03 2007-10-16 Cytoskeleton Inc. Methods for stabilizing proteins
US20050220978A1 (en) * 2004-03-31 2005-10-06 Cargill, Incorporated Dispersible protein composition
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
US20080019905A9 (en) * 2005-02-18 2008-01-24 Strome Scott E Method of using an anti-CD137 antibody as an agent for radioimmunotherapy or radioimmunodetection
CN101484470B (zh) * 2005-10-21 2014-07-23 阿伊沃生物制剂有限公司 具有增强的抗体依赖性细胞毒性活性的抗体及其生产方法和用途
RU2476442C2 (ru) 2007-03-29 2013-02-27 Эббот Лэборетриз Кристаллические антитела против il-12 человека
US20110229460A1 (en) * 2008-05-01 2011-09-22 Gtc Biotherapeutics, Inc. anti-cd137 antibody as an agent in the treatment of inflammatory conditions
NZ606283A (en) * 2008-11-28 2014-08-29 Abbvie Inc Stable antibody compositions and methods for stabilizing same
EP2435474A2 (en) 2009-05-27 2012-04-04 Baxter International Inc A method to produce a highly concentrated immunoglobulin preparation for subcutaneous use
US8993294B2 (en) 2009-08-10 2015-03-31 Danisco Us Inc. Cross-flow membrane filtration-based process for protein recovery
CA2872907A1 (en) 2012-05-09 2013-11-14 The University Of Akron Enzyme-based protein separation and enrichment from soy meal, wheat meal, and other protein-rich materials derived from plant seeds, fruits and other biomass
KR102163004B1 (ko) 2012-08-22 2020-10-07 크래프트 푸즈 그룹 브랜즈 엘엘씨 발효유 성분을 갖는 가공 치즈 및 제조 방법
EP3636657A1 (en) * 2018-10-08 2020-04-15 Ablynx N.V. Chromatography-free antibody purification method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431201A (en) * 1967-08-29 1969-03-04 Atomic Energy Commission Hyperfiltration process having ion exchange pretreatment
ES369944A1 (es) * 1969-07-26 1971-12-01 Inst Llorente S A Procedimiento para separar proteinas en estado de gran pu- reza a partir de mezclas complejas proteicas.
US3977967A (en) * 1973-05-10 1976-08-31 Union Carbide Corporation Ultrafiltration apparatus and process for the treatment of liquids
NL7603369A (en) * 1976-03-31 1977-10-04 Stichting Bedrijven Van Het Selective removal of inorganic ions from aq. protein concentrates - by ultrafiltration and diafiltration at controlled pH
FR2459619B1 (fr) * 1979-06-26 1983-07-29 Agronomique Inst Nat Rech Procede pour l'obtention a partir de lactoserum, d'un produit enrichi en alpha-lactalbumine et applications dudit procede
DE3432718C1 (de) * 1984-09-06 1986-05-22 Biotest Pharma GmbH, 6000 Frankfurt Verfahren zur Herstellung einer Loesung von Milch- und/oder Kolostralimmunglobulinen
FR2605322B1 (fr) * 1986-10-20 1989-04-28 Applic Tech Nles Procede de separation de certaines proteines du lactoserum ou du lait.

Also Published As

Publication number Publication date
IE64919B1 (en) 1995-09-20
US4897465A (en) 1990-01-30
IE893057L (en) 1990-04-12
NZ230993A (en) 1991-11-26
AU4257089A (en) 1990-04-26
CA1330050C (en) 1994-06-07
IL91781A (en) 1994-06-24
EP0363896B1 (en) 1994-08-10
MX163729B (es) 1992-06-17
IL91781A0 (en) 1990-06-10
DE68917407T2 (de) 1995-02-02
JPH02218691A (ja) 1990-08-31
AU624633B2 (en) 1992-06-18
ATE109792T1 (de) 1994-08-15
KR900005998A (ko) 1990-05-07
DE68917407D1 (de) 1994-09-15
EP0363896A2 (en) 1990-04-18
EP0363896A3 (en) 1991-08-14

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