ES2057571T3 - Receptor de pdgf-alfa. - Google Patents

Receptor de pdgf-alfa.

Info

Publication number
ES2057571T3
ES2057571T3 ES90908996T ES90908996T ES2057571T3 ES 2057571 T3 ES2057571 T3 ES 2057571T3 ES 90908996 T ES90908996 T ES 90908996T ES 90908996 T ES90908996 T ES 90908996T ES 2057571 T3 ES2057571 T3 ES 2057571T3
Authority
ES
Spain
Prior art keywords
pdgf
disclosed
dna molecules
alpha
receiver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90908996T
Other languages
English (en)
Inventor
James D Kelly
Mark J Murray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ES2057571T3 publication Critical patent/ES2057571T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

MOLECULAS AISLADAS DE ADN QUE CODIFICAN UN NUEVO RECEPTOR PDGF. EL RECEPTOR ENLAZA LAS ISOFORMAS AA, AB Y BB DEL PDGF CON ALTA AFINIDAD. TAMBIEN SE MUESTRAN LAS CELULAS TRANSFECTADAS O TRANSFORMADAS CON LAS MOLECULAS DE ADN. LAS CELULAS SE PUEDEN UTILIZAR DENTRO DE METODOS PARA LA DETECCION DE ACTIVIDAD AGONISTA O ANTAGONISTA EN UN COMPUESTO DE TEST.
ES90908996T 1989-05-22 1990-05-21 Receptor de pdgf-alfa. Expired - Lifetime ES2057571T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35501889A 1989-05-22 1989-05-22

Publications (1)

Publication Number Publication Date
ES2057571T3 true ES2057571T3 (es) 1994-10-16

Family

ID=23395910

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90908996T Expired - Lifetime ES2057571T3 (es) 1989-05-22 1990-05-21 Receptor de pdgf-alfa.

Country Status (10)

Country Link
US (2) US5371205A (es)
EP (1) EP0474744B1 (es)
JP (1) JPH04505260A (es)
AT (1) ATE109510T1 (es)
AU (1) AU5749690A (es)
CA (1) CA2057854C (es)
DE (1) DE69011329T2 (es)
DK (1) DK0474744T3 (es)
ES (1) ES2057571T3 (es)
WO (1) WO1990014425A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110737A (en) 1988-02-02 2000-08-29 The Regents Of The University Of California Human platelet-derived growth factor receptor, type A
US5468468A (en) * 1989-02-09 1995-11-21 The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services Method for making a monoclonal antibody, monoclonal antibodies to α PD
US6228600B1 (en) 1992-07-20 2001-05-08 The United States Of America As Represented By The Department Of Health And Human Services Immunoassays for the alpha platelet-derived growth factor receptor
CA2044626C (en) 1989-02-09 2001-10-16 Toshimitsu Matsui Type a platelet-derived growth factor receptor gene
JPH06503966A (ja) * 1990-12-21 1994-05-12 クリエイティブ　バイオモレキュルズ　インコーポレイテッド 生合成したｐｄｇｆアンタゴニスト
US6605442B1 (en) * 1992-03-19 2003-08-12 The Rockefeller University Methods of testing drugs or agents that modulate the activity of receptor recognition factors
US5326695A (en) * 1992-05-15 1994-07-05 Ludwig Institute For Cancer Research Platelet derived growth factor agonists
US5444151A (en) * 1992-05-15 1995-08-22 Ludwig Institute For Cancer Research Platelet derived growth factor antagonists
US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
US6107046A (en) * 1992-10-09 2000-08-22 Orion Corporation Antibodies to Flt4, a receptor tyrosine kinase and uses thereof
US5776755A (en) * 1992-10-09 1998-07-07 Helsinki University Licensing, Ltd. FLT4, a receptor tyrosine kinase
DE69942981D1 (de) 1998-10-09 2011-01-05 Vegenics Ltd Flt4 (vegfr-3) als ziel für tumornachweis (imaging) und antitumortherapie
US6667173B2 (en) 2000-12-01 2003-12-23 The Schepens Eye Research Institute Nucleic acids encoding platelet derived growth factor-alpha receptors
CN1494552A (zh) 2001-01-19 2004-05-05 ·��ά��֢�о�Ժ Flt4(VEGFR-3)作为靶用于肿瘤成像和抗肿瘤治疗
JP4588447B2 (ja) * 2002-08-09 2010-12-01 セラヴァンス， インコーポレーテッド 過剰増殖および関連疾患に関連するオンコキナーゼ融合ポリペプチド、これをコードする核酸、ならびにこれを検出する方法および同定する方法
KR20050085006A (ko) * 2002-11-15 2005-08-29 각고호우징 게이오기주크 ＰＤＧＦ수용체 α유전자의 엑손 1β및 그 이용
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
JP2008504002A (ja) 2003-11-12 2008-02-14 バイオジェン・アイデック・エムエイ・インコーポレイテッド 新生児Ｆｃレセプター（ＦｃＲｎ）結合ポリペプチド改変体、ダイマーＦｃ結合タンパク質、およびそれらに関連する方法
CN101137673B (zh) 2005-01-05 2013-12-04 比奥根艾迪克Ma公司 Cripto结合分子
WO2007021860A2 (en) * 2005-08-11 2007-02-22 Bayer Healthcare Llc QUANTITATIVE ASSAYS FOR PDGFR-β IN BODY FLUIDS
US20130216513A1 (en) 2010-07-09 2013-08-22 Biogen Idec Hemophilia Inc. Chimeric Clotting Factors
WO2013012733A1 (en) 2011-07-15 2013-01-24 Biogen Idec Ma Inc. Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto
CA2860579A1 (en) 2012-01-10 2013-07-18 Biogen Idec Ma Inc. Enhancement of transport of therapeutic molecules across the blood brain barrier
RS60026B1 (sr) 2013-02-18 2020-04-30 Vegenics Pty Ltd Molekuli koji vezuju ligande i njihove upotrebe
CN107636159B (zh) 2015-02-04 2022-06-14 百时美施贵宝公司 选择治疗性分子的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU607306B2 (en) * 1988-02-02 1991-02-28 Regents Of The University Of California, The Human platelet-derived growth factor receptor

Also Published As

Publication number Publication date
DE69011329D1 (de) 1994-09-08
CA2057854C (en) 2000-01-11
JPH04505260A (ja) 1992-09-17
ATE109510T1 (de) 1994-08-15
AU5749690A (en) 1990-12-18
US5371205A (en) 1994-12-06
DE69011329T2 (de) 1994-12-08
WO1990014425A1 (en) 1990-11-29
US5618678A (en) 1997-04-08
EP0474744A1 (en) 1992-03-18
DK0474744T3 (da) 1994-11-21
EP0474744B1 (en) 1994-08-03
CA2057854A1 (en) 1990-11-23

Similar Documents

Publication Publication Date Title
ES2057571T3 (es) Receptor de pdgf-alfa.
ES2183801T3 (es) Composiciones del receptor de acetilcolina nicotinico neuronal humano y procedimientos que lo usan.
TR200003461T2 (tr) Adenosin A3 Alıcı Modülatörleri
SE9601245D0 (sv) Chimeric superantigens and their use
PT694042E (pt) Inibidor do factor de crescimento de celulas endoteliais vasculares
FI972390A (fi) Sytokiini nimeltä Lerk-7
GB2215909B (en) Method and apparatus for the quantitative,depth differential analysis of solid samples with the use of two ion beams
MX9709265A (es) Superantigenos modificados/quimericos y sus usos.
MY108526A (en) Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
DE3063025D1 (en) Compositions, methods and elements for detecting or assaying peroxidatively active substances
NO171223C (no) Monoklonalt reseptormolekyl eller del derav som omfatter det antistoffbindende sete, for in vitro bruk, samt in vitro anvendelse derav
NO861979L (no) Uorganisk/polymerfiberkompositt, fremgangsmaate for fremstilling av denne og anvendelse innbefattende dimensjonsstabil separator.
SE9602062D0 (sv) Method for detection of mutations
EP0349988A3 (en) Method to determine a specific substance capable of binding
WO1998018430A3 (en) P2y receptor antagonists
MX9802730A (es) Agonistas receptores hematopoyeticos multifuncionales.
DK445187D0 (da) Apparat til undersoegelse af fejl i materialer, isaer i stoebegods
DK0862627T3 (da) Neuropeptid Y-Y5 receptor
ATE71149T1 (de) Monoklonale antikoerper.
WO1998002455A3 (en) Transcriptional intermediary factor-2 (tfif2)
DE69623280D1 (de) Inhibierung der amulin-freisetzung
AU6189486A (en) Monoclonal antibodies to prosomal proteins
NO984233L (no) Cytokin kalt lerk-8
GB9520411D0 (en) Method of testing
ES1024968U (es) Teja perfeccionada.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 474744

Country of ref document: ES