ES2056332T3 - (quinolin-2-il-metoxi)fenil-tioureas substituidas. - Google Patents

(quinolin-2-il-metoxi)fenil-tioureas substituidas.

Info

Publication number
ES2056332T3
ES2056332T3 ES90119313T ES90119313T ES2056332T3 ES 2056332 T3 ES2056332 T3 ES 2056332T3 ES 90119313 T ES90119313 T ES 90119313T ES 90119313 T ES90119313 T ES 90119313T ES 2056332 T3 ES2056332 T3 ES 2056332T3
Authority
ES
Spain
Prior art keywords
alkyl
halogen
optionally substituted
cyano
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90119313T
Other languages
English (en)
Inventor
Siegfried Dr Raddatz
Klaus Dr Mohrs
Burkhard Dr Fugmann
Romanis Fruchtmann
Christian Dr Kohlsdorfer
Reiner Prof Muller-Peddinghaus
Pia Dr Theisen-Popp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2056332T3 publication Critical patent/ES2056332T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A UNA QUINOLINA ETOXI ANILINA CON ISOCIANATO Y SE EMPLEA COMO MEDICAMENTO PARA INHIBIR LAS REACCIONES ENZIMATICAS DEL METABOLISMO DEL ACIDO ARAQUIDANICO.
ES90119313T 1989-10-21 1990-10-09 (quinolin-2-il-metoxi)fenil-tioureas substituidas. Expired - Lifetime ES2056332T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3935139A DE3935139A1 (de) 1989-10-21 1989-10-21 Substituierte (chinolin-2-yl-methoxy)phenyl-thioharnstoffe

Publications (1)

Publication Number Publication Date
ES2056332T3 true ES2056332T3 (es) 1994-10-01

Family

ID=6391944

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90119313T Expired - Lifetime ES2056332T3 (es) 1989-10-21 1990-10-09 (quinolin-2-il-metoxi)fenil-tioureas substituidas.

Country Status (8)

Country Link
US (1) US5120744A (es)
EP (1) EP0424722B1 (es)
JP (1) JPH03135957A (es)
AT (1) ATE108180T1 (es)
CA (1) CA2028042A1 (es)
DE (2) DE3935139A1 (es)
DK (1) DK0424722T3 (es)
ES (1) ES2056332T3 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204358A (en) * 1987-11-25 1993-04-20 Merck Frosst Canada, Inc. Hetaryl styryl quinolines as leukotriene inhibitors
KR20070001922A (ko) 2003-12-12 2007-01-04 와이어쓰 심장혈관질환 치료에 유용한 퀴놀린

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5764675A (en) * 1980-10-07 1982-04-19 Nissan Chem Ind Ltd Substituted phenylurea derivative, its preparation, and selective herbicide containing said compound
US4425343A (en) * 1980-10-24 1984-01-10 Nissan Chemical Industries, Ltd. Benzoazine ether or thioether linkage containing urea compounds, process for producing same and insecticides containing said compounds
JPS5772968A (en) * 1980-10-24 1982-05-07 Nissan Chem Ind Ltd Aniline derivative and its preparation
US4530931A (en) * 1983-01-03 1985-07-23 Usv Pharmaceutical Corp. 8-Quinoline carbanilates for the inhibition of lipolysis
IE58870B1 (en) * 1985-03-08 1993-11-17 Leo Pharm Prod Ltd Pyridine derivatives
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4732978A (en) * 1985-10-03 1988-03-22 American Home Products Corporation Novel substituted naphthyloxymethyl quinoline derivatives as anti-inflammatory and antiallergy agents
EP0256985A3 (de) * 1986-08-15 1989-11-15 Ciba-Geigy Ag Substituierte Thioharnstoffe, Isothioharnstoffe und Carbodiimide
US4769461A (en) * 1986-09-16 1988-09-06 American Home Products Corporation Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents
ATE70976T1 (de) * 1987-03-18 1992-01-15 American Home Prod Sulfonylcarboxamide.
US4769387A (en) * 1987-11-13 1988-09-06 Abbott Laboratories Dibenzofuran lipoxygenase inhibiting compounds, compositions and use
DE3908298A1 (de) * 1989-03-14 1990-09-20 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-n,n'-sulfonylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
US5120744A (en) 1992-06-09
EP0424722A3 (en) 1991-10-09
ATE108180T1 (de) 1994-07-15
DE3935139A1 (de) 1991-04-25
DE59006355D1 (de) 1994-08-11
CA2028042A1 (en) 1991-04-22
DK0424722T3 (da) 1994-10-17
EP0424722B1 (de) 1994-07-06
JPH03135957A (ja) 1991-06-10
EP0424722A2 (de) 1991-05-02

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