ES2054095T3 - Procedimiento para la preparacion de nuevos derivados tieniloxi-alquilaminicos. - Google Patents

Procedimiento para la preparacion de nuevos derivados tieniloxi-alquilaminicos.

Info

Publication number
ES2054095T3
ES2054095T3 ES89890235T ES89890235T ES2054095T3 ES 2054095 T3 ES2054095 T3 ES 2054095T3 ES 89890235 T ES89890235 T ES 89890235T ES 89890235 T ES89890235 T ES 89890235T ES 2054095 T3 ES2054095 T3 ES 2054095T3
Authority
ES
Spain
Prior art keywords
pct
date
alkyl
tieniloxi
alquilaminicos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89890235T
Other languages
English (en)
Inventor
Dieter Dr Binder
Gerhard Dr Dipl-Ing Greier
Franz Dr Dipl-Ing Rovenszky
Friedrich Dr Dipl-I Hillebrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ebewe Pharma GmbH Nfg KG
Original Assignee
Ebewe Pharma GmbH Nfg KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ebewe Pharma GmbH Nfg KG filed Critical Ebewe Pharma GmbH Nfg KG
Application granted granted Critical
Publication of ES2054095T3 publication Critical patent/ES2054095T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Abstract

EL INVENTO SE REFIERE A UN NUEVO DERIVADO TIENILOXI-ALQUILAMINO DE FORMULA (I), TRATA DE LAS SALES DE ADICION DE ACIDOS Y DESCRIBE LA APLICACION DEL COMPUESTO DE FORMULA (I) PARA EL TRATAMIENTO DE PERTURBACIONES DEL RITMO CARDIACO. SIENDO: R1 HIDROGENO, HALOGENO, ALQUILO, CF3 O ALCOXI; R2 Y R3 IGUALES O DIFRENTES, ALQUILO, CICLOALQUILO, ALQUENILO O ALQUINILO DE C8; EL RESTO DE FORMULA (II) SE COLOCA EN EL ANILLO TIOFENO EN POSICION 4 O 5 Y N UN NUMERO ENTERO DE 1 A 5. TOMANDO R2 Y R3 CON EL NITROGENO UN ANILLO SATURADO DE CINCO A 7 MIEMBROS O UN ANILLO HETEROCICLICO SATURADO QUE CONTIENE EN EL ANILLO UN ATOMO DE OXIGENO O NITROGENO Y SE SUBSTITUYE EL NITROGENO ADICIONAL A TRAVES DE UN RESTO ALQUILO DE C1 A 3.
ES89890235T 1988-09-15 1989-09-12 Procedimiento para la preparacion de nuevos derivados tieniloxi-alquilaminicos. Expired - Lifetime ES2054095T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0226688A AT391316B (de) 1988-09-15 1988-09-15 Neue thienyloxy-alkylamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES2054095T3 true ES2054095T3 (es) 1994-08-01

Family

ID=3531160

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89890235T Expired - Lifetime ES2054095T3 (es) 1988-09-15 1989-09-12 Procedimiento para la preparacion de nuevos derivados tieniloxi-alquilaminicos.

Country Status (12)

Country Link
US (1) US5100911A (es)
EP (1) EP0360784B1 (es)
JP (1) JP2834506B2 (es)
AT (2) AT391316B (es)
AU (1) AU620646B2 (es)
CA (1) CA1338716C (es)
DE (1) DE58902884D1 (es)
ES (1) ES2054095T3 (es)
GR (1) GR3007087T3 (es)
HU (1) HU208970B (es)
WO (1) WO1990002743A1 (es)
ZA (1) ZA896991B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
FR2764800B1 (fr) * 1997-06-23 1999-09-10 Sanofi Sa Composition pharmaceutique solide contenant des derives de benzofuranne
FR2813308B1 (fr) * 2000-08-23 2005-07-01 Sanofi Synthelabo Aminoalkoxybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation ainsi que les compositions les contenant
FR2813307B1 (fr) * 2000-08-23 2002-11-08 Sanofi Synthelabo Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
FR2813306B1 (fr) * 2000-08-23 2005-10-21 Sanofi Synthelabo Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
FR2967067A1 (fr) 2010-11-10 2012-05-11 Sanofi Aventis Composition pharmaceutique et forme galenique a base de dronedarone et son procede de preparation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1297109C (en) * 1986-01-17 1992-03-10 Dieter Binder 2-pyridinyl or 2-quinolinyl-methoxy-thiophene derivatives
FR2600065B1 (fr) * 1986-06-13 1988-09-09 Roussel Uclaf Nouveaux derives de l'acide 5-((2-benzofuranyl) carbonyl) thiophene acetique, leurs sels, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
DE3770117D1 (de) * 1986-10-29 1991-06-20 Binder Dieter Neue 1-/ 3-(2-dialkylaminoaethoxy)-2-thienyl/-3-phenyl-1-propanone und ihre saeureadditionssalze und verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Also Published As

Publication number Publication date
JPH03501389A (ja) 1991-03-28
AU4301189A (en) 1990-04-02
HU208970B (en) 1994-02-28
ATA226688A (de) 1990-03-15
AT391316B (de) 1990-09-25
WO1990002743A1 (de) 1990-03-22
EP0360784B1 (de) 1992-12-02
DE58902884D1 (de) 1993-01-14
GR3007087T3 (es) 1993-07-30
HUT58086A (en) 1992-01-28
AU620646B2 (en) 1992-02-20
EP0360784A1 (de) 1990-03-28
JP2834506B2 (ja) 1998-12-09
HU895522D0 (en) 1990-09-28
US5100911A (en) 1992-03-31
CA1338716C (en) 1996-11-12
ATE82972T1 (de) 1992-12-15
ZA896991B (en) 1990-06-27

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