ES2053908T3 - Proceso mejorado para la sintesis de acido 3-cloro-2,4,5-trifluorobenzoico. - Google Patents

Proceso mejorado para la sintesis de acido 3-cloro-2,4,5-trifluorobenzoico.

Info

Publication number
ES2053908T3
ES2053908T3 ES89120030T ES89120030T ES2053908T3 ES 2053908 T3 ES2053908 T3 ES 2053908T3 ES 89120030 T ES89120030 T ES 89120030T ES 89120030 T ES89120030 T ES 89120030T ES 2053908 T3 ES2053908 T3 ES 2053908T3
Authority
ES
Spain
Prior art keywords
chloro
trifluorobenzoic acid
improved process
synthesis
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89120030T
Other languages
English (en)
Inventor
James Norton Wemple
Floyd Gregory Spence
Gregory Lee Karrick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of ES2053908T3 publication Critical patent/ES2053908T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ES DESCRITO UN PROCESO MEJORADO PARA LA PREPARACION DEL ACIDO TRIFLUOROBENZOICO-2,4,5-CLORO-3 QUE CONCIERNE A LA REACCION DE UN DIESTER DEL ACIDO BENCENODICARBOXILICO-1,2-TETRAFLUORO-3,4,5,6 CON UN AMINO SUSTITUIDO PARA DAR EL ACIDO TRIFLUOROBENZOICO-2,4,5-AMINO-3 SEGUIDO POR LA SUBSECUENTE CONVERSION DEL AMINO INTERMEDIO EN ACIDO TRIFLUOROBENZOICO-2,4,5-CLORO-3.
ES89120030T 1988-10-28 1989-10-27 Proceso mejorado para la sintesis de acido 3-cloro-2,4,5-trifluorobenzoico. Expired - Lifetime ES2053908T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/264,296 US4885386A (en) 1988-10-28 1988-10-28 Process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic acid

Publications (1)

Publication Number Publication Date
ES2053908T3 true ES2053908T3 (es) 1994-08-01

Family

ID=23005412

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89120030T Expired - Lifetime ES2053908T3 (es) 1988-10-28 1989-10-27 Proceso mejorado para la sintesis de acido 3-cloro-2,4,5-trifluorobenzoico.

Country Status (11)

Country Link
US (1) US4885386A (es)
EP (1) EP0366149B1 (es)
JP (1) JP2886908B2 (es)
AT (1) ATE84518T1 (es)
CA (1) CA1313883C (es)
DE (1) DE68904395T2 (es)
DK (1) DK537789A (es)
ES (1) ES2053908T3 (es)
GR (1) GR3006784T3 (es)
IE (1) IE63335B1 (es)
PT (1) PT92117B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3631906A1 (de) * 1986-09-19 1988-03-31 Bayer Ag Verfahren zur herstellung von benzoesaeure-derivaten
GB2289048A (en) * 1993-10-12 1995-11-08 Nippon Catalytic Chem Ind Process for producing 3-substituted 2,4,5-trifluorobenzoic acid,and 4-amino-3,5,6-trifluorophthalic acid
ES2126798T3 (es) * 1994-02-23 1999-04-01 Asahi Glass Co Ltd Procedimiento de preparacion de anhidrido tetrafluoroftalico.
CN109293513B (zh) * 2018-10-09 2021-10-08 江西富祥药业股份有限公司 一种西他沙星中间体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3044904A1 (de) * 1980-11-28 1982-07-01 Basf Ag, 6700 Ludwigshafen Fluorierte anthranilsaeure und anthranilsaeurenitril sowie verfahren zu ihrer herstellung
DE3142856A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4-dichlor-5-fluor-benzoylchlorid
IN162769B (es) * 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
US4771054A (en) * 1985-01-23 1988-09-13 Warner-Lambert Company Antibacterial agents
AU5427286A (en) * 1985-03-08 1986-09-11 Kyorin Pharmaceutical Co. Ltd. 7-(1-pyrrolidinyl)-3-quinolinecarboxylic acid derivatives
US4782180A (en) * 1985-09-09 1988-11-01 Warner-Lambert Company Process for tetrafluorobenzoic acid
DE3631906A1 (de) * 1986-09-19 1988-03-31 Bayer Ag Verfahren zur herstellung von benzoesaeure-derivaten
US4782179A (en) * 1987-02-13 1988-11-01 Nippon Shokubai Kagaku Kogyo Co., Ltd. 3-amino-2,4,5-trifluorobenzoic acid and a method for manufacture thereof

Also Published As

Publication number Publication date
GR3006784T3 (es) 1993-06-30
DE68904395D1 (de) 1993-02-25
EP0366149A1 (en) 1990-05-02
JPH02178254A (ja) 1990-07-11
EP0366149B1 (en) 1993-01-13
JP2886908B2 (ja) 1999-04-26
ATE84518T1 (de) 1993-01-15
IE893478L (en) 1990-04-28
CA1313883C (en) 1993-02-23
DK537789A (da) 1990-04-29
IE63335B1 (en) 1995-04-19
PT92117A (pt) 1990-04-30
DK537789D0 (da) 1989-10-27
DE68904395T2 (de) 1993-05-06
PT92117B (pt) 1995-06-30
US4885386A (en) 1989-12-05

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