ES2053575T3 - Lipasas y extractos lipasicos, su procedimiento de preparacion y su aplicacion en terapeutica. - Google Patents

Lipasas y extractos lipasicos, su procedimiento de preparacion y su aplicacion en terapeutica.

Info

Publication number
ES2053575T3
ES2053575T3 ES87401984T ES87401984T ES2053575T3 ES 2053575 T3 ES2053575 T3 ES 2053575T3 ES 87401984 T ES87401984 T ES 87401984T ES 87401984 T ES87401984 T ES 87401984T ES 2053575 T3 ES2053575 T3 ES 2053575T3
Authority
ES
Spain
Prior art keywords
lipasic
lipases
therapeutics
extracts
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87401984T
Other languages
English (en)
Inventor
Herve Moreau
Robert Verger
Daniel Lecat
Jean-Louis Junien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jouveinal SA
Original Assignee
Jouveinal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal SA filed Critical Jouveinal SA
Application granted granted Critical
Publication of ES2053575T3 publication Critical patent/ES2053575T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)

Abstract

SE HACE SUBIR EN ESTOMAGOS DE CONEJOS O DE CABALLOS UNA EXTRACCION POR UN MEDIO ACUOSO ACIDO, SE AUMENTE EL EXTRACTO LIPASICO POR ADICION DE SALES HIDROSOLUBLES, DESPUES, POR UNA FILTRACION SOBRE TAMIZ MOLECULAR, SEGUIDAMENTE UNA SEPARACION POR CROMATOGRAFIA DE INTERCAMBIO IONICO, SE RECOGE UNA FRACCION DE ELUCION CONTENIENDO LA LIPASA. SE EMPLEA COMO MEDICAMENTO PARA LUCHAR CONTRA LAS MALAS ABSORCIONES GASTRICAS DE MATERIAS GRASAS.
ES87401984T 1986-09-17 1987-09-04 Lipasas y extractos lipasicos, su procedimiento de preparacion y su aplicacion en terapeutica. Expired - Lifetime ES2053575T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8612996A FR2603804B1 (fr) 1986-09-17 1986-09-17 Lipases et extraits lipasiques, leur procede de preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES2053575T3 true ES2053575T3 (es) 1994-08-01

Family

ID=9339032

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87401984T Expired - Lifetime ES2053575T3 (es) 1986-09-17 1987-09-04 Lipasas y extractos lipasicos, su procedimiento de preparacion y su aplicacion en terapeutica.

Country Status (17)

Country Link
US (1) US5075231A (es)
EP (1) EP0261016B1 (es)
JP (1) JPS6379589A (es)
KR (1) KR960011522B1 (es)
AT (1) ATE86661T1 (es)
AU (1) AU602349B2 (es)
CA (1) CA1308678C (es)
DE (1) DE3784607T2 (es)
DK (1) DK483087A (es)
ES (1) ES2053575T3 (es)
FI (1) FI87232C (es)
FR (1) FR2603804B1 (es)
IE (1) IE59972B1 (es)
IS (1) IS3251A7 (es)
NO (1) NO170316C (es)
NZ (1) NZ221568A (es)
ZA (1) ZA876322B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2683549B1 (fr) * 1991-11-13 1994-11-18 Jouveinal Inst Rech Acides nucleiques codant pour la lipase gastrique de lapin et derives polypeptidiques, leur utilisation pour la production de ces polypeptides, et compositions pharmaceutiques a base de ces derniers.
US5998189A (en) * 1992-12-16 1999-12-07 Warner-Lambert Company Polypeptide derivatives of dog gastric lipase and pharmaceutical compositions containing same
FR2699179B1 (fr) * 1992-12-16 1995-01-06 Jouveinal Inst Rech Acides nucléiques codant pour la lipase gastrique de chien et dérivés polypeptidiques, leur utilisation pour la production de ces polypeptides, et compositions pharmaceutiques à base de ces derniers.
FR2733249B1 (fr) * 1995-04-20 1997-06-06 Biocem Lipase gastrique de chien recombinante et polypeptides derives produits par les plantes, leurs procedes d'obtention et leurs utilisations
JP2000026311A (ja) * 1998-07-02 2000-01-25 Amano Pharmaceut Co Ltd 胃排出能亢進剤組成物
US6770468B1 (en) 1999-09-14 2004-08-03 Genzyme Glycobiology Research Institute, Inc. Phosphodiester-α-GlcNAcase of the lysosomal targeting pathway
US6534300B1 (en) 1999-09-14 2003-03-18 Genzyme Glycobiology Research Institute, Inc. Methods for producing highly phosphorylated lysosomal hydrolases
WO2001049282A2 (en) * 2000-01-06 2001-07-12 Martek Biosciences Corporation Therapeutic preparations of highly unsaturated fatty acids
EP1149585A1 (en) * 2000-04-27 2001-10-31 Warner-Lambert Company Use of recombinant gastric lipase for treating functional dyspepsia
US6800472B2 (en) 2001-12-21 2004-10-05 Genzyme Glycobiology Research Institute, Inc. Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase
US6905856B2 (en) 2001-12-21 2005-06-14 Genzyme Glycobiology Research Institute, Inc. Soluble GlcNAc phosphotransferase
DE102005010604B3 (de) * 2005-03-06 2006-07-20 Lange Uhren Gmbh Uhr
KR100828146B1 (ko) * 2006-04-28 2008-05-08 김우식 췌장 리파아제의 선택적 추출방법
EP1870649A1 (en) 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
US8221747B2 (en) 2007-02-20 2012-07-17 Aptalis Pharma Limited Stable pancreatic enzyme compositions
CA2702577A1 (en) 2007-10-15 2009-04-23 Jbs United, Inc. Method for increasing performance of offspring
SI2621476T1 (sl) 2010-10-01 2014-12-31 Aptalis Pharma Limited Gastrorezistentne obloĹľene pankrelipazne formulacije z nizko trdnostjo
ES2558756T3 (es) 2011-08-08 2016-02-08 Aptalis Pharma Limited Método para la prueba de disolución de composiciones sólidas que contienen enzimas digestivas
ES2784227T3 (es) 2013-08-09 2020-09-23 Allergan Pharmaceuticals Int Ltd Composición de enzimas digestivos adecuada para la administración entérica
BR112016000658A2 (pt) * 2013-11-05 2018-03-20 Allergan Pharmaceuticals International Limited pancreatina de alta atividade, processo para a preparação de pancreatina de aa tendo atividade lipásica específica de pelo menos aproximadamente 120 usp iu/mg e método de tratamento de um paciente sujeito a uma condição patológica associada com a insuficiência enzimática pandreática
CA2947998A1 (en) 2014-06-19 2015-12-23 Aptalis Pharma Ltd. Methods for removing viral contaminants from pancreatic extracts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3256150A (en) * 1964-04-20 1966-06-14 Dairyland Food Lab Method for treating malabsorption syndrome
GB1139991A (en) * 1965-07-19 1969-01-15 Armour Pharma Stabilized enzyme composition
FR6622M (es) * 1967-09-12 1969-01-13
GB2142337A (en) * 1983-07-01 1985-01-16 Celltech Ltd Preparation of lingual lipase protein
GB8421210D0 (en) * 1984-08-21 1984-09-26 Celltech Ltd Polypeptide and polypeptide composition

Also Published As

Publication number Publication date
AU7795687A (en) 1988-03-24
DK483087D0 (da) 1987-09-15
DE3784607T2 (de) 1993-10-07
NZ221568A (en) 1991-11-26
NO170316B (no) 1992-06-29
NO873885L (no) 1988-03-18
NO873885D0 (no) 1987-09-16
FI874038A0 (fi) 1987-09-16
DK483087A (da) 1988-03-18
CA1308678C (en) 1992-10-13
DE3784607D1 (de) 1993-04-15
ATE86661T1 (de) 1993-03-15
NO170316C (no) 1992-10-07
US5075231A (en) 1991-12-24
FR2603804B1 (fr) 1989-10-27
IE872401L (en) 1988-03-17
KR880004084A (ko) 1988-06-01
FI87232C (fi) 1992-12-10
AU602349B2 (en) 1990-10-11
FI874038A (fi) 1988-03-18
JPS6379589A (ja) 1988-04-09
EP0261016A1 (fr) 1988-03-23
IE59972B1 (en) 1994-05-04
EP0261016B1 (fr) 1993-03-10
IS3251A7 (is) 1987-11-30
KR960011522B1 (ko) 1996-08-23
ZA876322B (en) 1988-03-02
FR2603804A1 (fr) 1988-03-18
FI87232B (fi) 1992-08-31

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