ES2051682T3 - Un procedimiento para la preparacion de una composicion de liberacion mantenida. - Google Patents

Un procedimiento para la preparacion de una composicion de liberacion mantenida.

Info

Publication number
ES2051682T3
ES2051682T3 ES86114067T ES86114067T ES2051682T3 ES 2051682 T3 ES2051682 T3 ES 2051682T3 ES 86114067 T ES86114067 T ES 86114067T ES 86114067 T ES86114067 T ES 86114067T ES 2051682 T3 ES2051682 T3 ES 2051682T3
Authority
ES
Spain
Prior art keywords
release composition
procedure
preparation
maintenance release
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES86114067T
Other languages
English (en)
Inventor
Keiji Fujioka
Shigeji Sato
Nobuhiko Tamura
Yoshihiro Takada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61223251A external-priority patent/JPH0761959B2/ja
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Application granted granted Critical
Publication of ES2051682T3 publication Critical patent/ES2051682T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/2036—Silicones; Polysiloxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPOSICION DE LIBERACION LENTA, APLICABLE A SERES HUMANOS Y MAMIFEROS, QUE COMPRENDE (A) UN ELASTOMERO DE SILICONA Y (B) UNA SUSTANCIA FARMACEUTICA OPCIONALMENTE CON (C) ALBUMINA. CUANDO LA SUSTANCIA FARMACEUTICA ES DE PESO MOLECULAR GRANDE Y PUEDE EJERCER SU EFECTO FARMACEUTICO EN CANTIDADES TRAZA, SU LIBERACION CONTINUA DURANTE UN PROLONGADO PERIODO DE TIEMPO SE LOGRA POR APLICACION DE ESTA INVENCION.
ES86114067T 1985-10-11 1986-10-10 Un procedimiento para la preparacion de una composicion de liberacion mantenida. Expired - Lifetime ES2051682T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22759085 1985-10-11
JP61223251A JPH0761959B2 (ja) 1985-10-11 1986-09-19 シリコンエラストマ−系徐放性製剤
JP61223250A JPS62174031A (ja) 1985-10-11 1986-09-19 高分子量薬物含有徐放性製剤

Publications (1)

Publication Number Publication Date
ES2051682T3 true ES2051682T3 (es) 1994-07-01

Family

ID=27330754

Family Applications (1)

Application Number Title Priority Date Filing Date
ES86114067T Expired - Lifetime ES2051682T3 (es) 1985-10-11 1986-10-10 Un procedimiento para la preparacion de una composicion de liberacion mantenida.

Country Status (7)

Country Link
US (1) US4985253A (es)
EP (1) EP0219076B1 (es)
AT (1) ATE73321T1 (es)
AU (1) AU594088B2 (es)
DE (1) DE3684220D1 (es)
ES (1) ES2051682T3 (es)
NZ (1) NZ217844A (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR870005646A (ko) * 1985-12-16 1987-07-06 로버트 엘. 미니어 수술후 유착형성 억제방법
US4889722A (en) * 1985-12-16 1989-12-26 Ethicon, Inc. Method for inhibiting post-surgical adhesion formation by the topical administration of tissue plasminogen activator
US4761289A (en) * 1986-10-10 1988-08-02 International Minerals & Chemical Corp. Sustained release implant and method for preparing same
US5028430A (en) * 1987-05-08 1991-07-02 Syntex (U.S.A.) Inc. Delivery systems for the controlled administration of LHRH analogs
AU621305B2 (en) * 1987-07-01 1992-03-12 Genentech Inc. Method and therapeutic compositions for the prevention of fibrin deposition or adhesions
JPH01186823A (ja) * 1988-01-21 1989-07-26 Dow Corning Kk 薬物透過性物質の製造方法
FR2650502B1 (fr) * 1989-08-07 1994-05-27 Delagrange Laboratoires Nouvelle forme galenique orale ameliorant la biodisponibilite
FR2653338B1 (fr) * 1989-10-23 1994-06-10 Dow Corning Sa Formulation pour des pansements a liberation prolongee de medicament et son utilisation.
US5273965A (en) * 1992-07-02 1993-12-28 Cambridge Biotech Corporation Methods for enhancing drug delivery with modified saponins
US5650398A (en) * 1992-07-02 1997-07-22 Cambridge Biotech Corporation Drug delivery enhancement via modified saponins
IL110787A0 (en) * 1993-08-27 1994-11-11 Sandoz Ag Biodegradable polymer, its preparation and pharmaceutical composition containing it
JP3720386B2 (ja) * 1993-12-27 2005-11-24 住友製薬株式会社 薬物放出制御製剤
EP0759761A1 (en) * 1994-03-18 1997-03-05 Alfred Schmidt The use of dimeticone for the local antibacterial therapy and/or the prevention and therapy of helicobacter pylori (hp) associated syndromes and infectious diseases
DE4409357C2 (de) * 1994-03-18 1996-10-17 Upmeyer Hans Juergen Verwendung von Dimeticon zur Eradikation von Heliobacter pylori
US6028062A (en) * 1995-03-15 2000-02-22 Upmeyer; Hans-Juergen Use of dimeticone for the local antibacterial therapy and/or the prevention and therapy of helicobacter pylori (Hp) associated syndromes and infectious diseases
US5908621A (en) 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
DE69632062T2 (de) 1995-11-02 2004-11-18 Schering Corp. Kontinuierliche, niedrigdosierte zytokine-infusionstherapie
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
TW586944B (en) 1998-05-29 2004-05-11 Sumitomo Pharma Controlled release agent having a multi-layer structure
ES2360180T3 (es) * 1998-09-10 2011-06-01 Dainippon Sumitomo Pharma Co., Ltd. Preparación de liberación mantenida de larga duración de un fármaco.
US6056976A (en) * 1998-11-12 2000-05-02 Leiras Oy Elastomer, its preparation and use
TW524696B (en) * 1999-11-10 2003-03-21 Sumitomo Pharma Sustained-release drug formulations
US6812205B2 (en) 2000-03-15 2004-11-02 The Brigham & Women's Hospital, Inc. Suppression of vascular disorders by mucosal administration of heat shock protein peptides
WO2001093826A1 (fr) * 2000-06-06 2001-12-13 Sumitomo Pharmaceuticals Company, Limited Preparations polymere synthetiques biocompatibles
NZ529347A (en) 2001-04-04 2008-01-31 Nordic Vaccine Technology As Use of at least one sterol capable of interacting with a nucleic acid and at least saponin to form immunostimulating complexes ( IMSCO )
PT1629844E (pt) 2004-07-13 2007-10-17 Bayer Schering Pharma Oy Sistema de distribuição a longo prazo com distribuição súbita inicial controlada
US7857856B2 (en) * 2005-03-15 2010-12-28 Warsaw Ortho Pedic, Inc. Composite spinal nucleus implant with water absorption and swelling capabilities
EP1874334A4 (en) * 2005-04-15 2011-03-30 Vascular Biogenics Ltd COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
WO2012018069A1 (ja) 2010-08-06 2012-02-09 大日本住友製薬株式会社 脊髄損傷治療用製剤
US11173291B2 (en) * 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11338119B2 (en) * 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US4004979A (en) * 1968-03-29 1977-01-25 Agence Nationale De Valorisation De La Recherche (Anvar) Preparation of active proteins cross-linked to inactive proteins
US4464468A (en) * 1968-03-29 1984-08-07 Agence Nationale De Valorisation De La Recherche (Anvar) Immobilization of active protein by cross-linking to inactive protein
BE791632A (fr) * 1971-11-20 1973-05-21 Schering Ag Supports a base de caoutchouc siliconique pour agents medicamenteux
DE2445971A1 (de) * 1974-09-24 1976-04-08 Schering Ag Arzneimittelwirkstofftraeger ii
US4053580A (en) * 1975-01-01 1977-10-11 G. D. Searle & Co. Microsealed pharmaceutical delivery device
US4391797A (en) * 1977-01-05 1983-07-05 The Children's Hospital Medical Center Systems for the controlled release of macromolecules
US4164560A (en) * 1977-01-05 1979-08-14 Folkman Moses J Systems for the controlled release of macromolecules
JPS5470384A (en) * 1977-08-22 1979-06-06 Inst Obu Kiyansaa Risaachi Roi High molecular complex
JPS54147916A (en) * 1978-05-12 1979-11-19 Sumitomo Chem Co Ltd Preparation of urokinase injection
US4191741A (en) * 1978-09-22 1980-03-04 Eli Lilly And Company Removable drug implant
US4376765A (en) * 1980-03-31 1983-03-15 Institut International De Pathologie Cellulaire Et Moleculaire Medicaments, their preparation and compositions containing same
US4357312A (en) * 1981-07-16 1982-11-02 The Children's Hospital Medical Center Method of making prolonged release body
US4478596A (en) * 1982-11-26 1984-10-23 Michelson Paul E Delivery system for physiologically active agents
US4613330A (en) * 1982-11-26 1986-09-23 Michelson Paul E Delivery system for desired agents
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
DE3484951D1 (de) * 1983-10-14 1991-09-26 Sumitomo Pharma Verlaengerte praeparate mit verzoegerter abgabe.
GB8400653D0 (en) * 1984-01-11 1984-02-15 Beecham Group Plc Conjugates
US4591496A (en) * 1984-01-16 1986-05-27 Massachusetts Institute Of Technology Process for making systems for the controlled release of macromolecules
US4559054A (en) * 1984-08-09 1985-12-17 Research Corporation Rate-controlled drug release system
US4650772A (en) * 1984-08-09 1987-03-17 Abbott Laboratories Monoclonal antibody stabilization
AU561608B1 (en) * 1985-11-04 1987-05-14 Paco Research Corp. Transdermal vasoactive delivery

Also Published As

Publication number Publication date
DE3684220D1 (de) 1992-04-16
AU6385486A (en) 1987-04-16
NZ217844A (en) 1989-10-27
US4985253A (en) 1991-01-15
AU594088B2 (en) 1990-03-01
EP0219076A3 (en) 1988-04-20
EP0219076A2 (en) 1987-04-22
ATE73321T1 (de) 1992-03-15
EP0219076B1 (en) 1992-03-11

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