ES2014429B3 - Nuevas 4-triazol-4,3-a 1,4-benzodiazepinas, procedimiento para su preparacion, su aplicacion como medicamentos y preparaciones que las contienen. - Google Patents

Nuevas 4-triazol-4,3-a 1,4-benzodiazepinas, procedimiento para su preparacion, su aplicacion como medicamentos y preparaciones que las contienen.

Info

Publication number
ES2014429B3
ES2014429B3 ES86402763T ES86402763T ES2014429B3 ES 2014429 B3 ES2014429 B3 ES 2014429B3 ES 86402763 T ES86402763 T ES 86402763T ES 86402763 T ES86402763 T ES 86402763T ES 2014429 B3 ES2014429 B3 ES 2014429B3
Authority
ES
Spain
Prior art keywords
benzodiazepines
triazol
drugs
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES86402763T
Other languages
English (en)
Inventor
Francois Clemence
Martret Odile Le
Francoise Delevallee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of ES2014429B3 publication Critical patent/ES2014429B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
ES86402763T 1985-12-13 1986-12-11 Nuevas 4-triazol-4,3-a 1,4-benzodiazepinas, procedimiento para su preparacion, su aplicacion como medicamentos y preparaciones que las contienen. Expired - Lifetime ES2014429B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8518481A FR2591596B1 (fr) 1985-12-13 1985-12-13 Nouvelles 4h-triazolo(4,3-a)(1,4)benzodiazepines, leur procede de preparation, leur application comme medicaments et les compositions les renfermant

Publications (1)

Publication Number Publication Date
ES2014429B3 true ES2014429B3 (es) 1990-07-16

Family

ID=9325756

Family Applications (1)

Application Number Title Priority Date Filing Date
ES86402763T Expired - Lifetime ES2014429B3 (es) 1985-12-13 1986-12-11 Nuevas 4-triazol-4,3-a 1,4-benzodiazepinas, procedimiento para su preparacion, su aplicacion como medicamentos y preparaciones que las contienen.

Country Status (7)

Country Link
US (1) US4987131A (es)
EP (1) EP0227539B1 (es)
JP (1) JPH0788387B2 (es)
CA (1) CA1265794A (es)
DE (1) DE3671451D1 (es)
ES (1) ES2014429B3 (es)
FR (1) FR2591596B1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91386A0 (en) * 1988-08-24 1990-04-29 Boehringer Ingelheim Kg Method for treating autoimmune diseases by using a paf antagonist and pharmaceutical compositions comprising it
US7144880B2 (en) 1999-04-30 2006-12-05 Regents Of The University Of Michigan Compositions relating to novel compounds and targets thereof
EP2062583B1 (en) 1999-04-30 2012-12-26 The Regents of the University of Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7119088B2 (en) * 2003-02-19 2006-10-10 Pfizer Inc. Triazole compounds useful in therapy
EP1845996A4 (en) 2005-01-03 2009-04-29 Univ Michigan COMPOSITIONS AND METHODS RELATING TO NEW COMPOUNDS AND TARGETS
WO2007053193A2 (en) 2005-06-01 2007-05-10 The Regents Of The University Of Michigan Unsolvated benzodiazepine compositions and methods
CA2628193C (en) 2005-11-01 2012-08-14 The Regents Of The University Of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
MX2008015488A (es) 2006-06-09 2009-02-12 Univ Michigan Composiciones y metodos relacionados con compuestos novedosos y objetivos de los mismos.
MX2009009645A (es) 2007-03-09 2009-11-19 Univ Michigan Composiciones y metodos relacionados con nuevos compuestos y objetivos de los mismos.
CA2698248C (en) 2007-09-14 2017-08-29 The Regents Of The University Of Michigan Phenyl acyl guanidine derivatives as f1f0-atpase inhibitors and the use thereof
AU2008323945B2 (en) 2007-11-06 2013-11-28 The Regents Of The University Of Michigan Benzodiazepinone compounds useful in the treatment of skin conditions
AU2009291632B2 (en) 2008-09-11 2013-04-04 The Regents Of The University Of Michigan Aryl guanidine F1F0-ATPase inhibitors and related methods
US8604023B2 (en) 2009-04-17 2013-12-10 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
WO2011035124A1 (en) 2009-09-18 2011-03-24 The Regents Of The University Of Michigan Benzodiazepinone compounds and methods of treatment using same
CA2780333C (en) 2009-11-17 2016-05-24 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
WO2011062766A2 (en) 2009-11-17 2011-05-26 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
EP3535253A1 (en) 2016-11-01 2019-09-11 H. Hoffnabb-La Roche Ag 1,3-dihydro-1,4-benzodiazepine-2-thiones for the treatment of cns related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3734922A (en) * 1971-05-11 1973-05-22 Upjohn Co Certain 4h-s-triazolo(4,3-a)(1,4)benzodiazepines
JPS4951299A (es) * 1972-07-13 1974-05-18
US3880877A (en) * 1972-11-03 1975-04-29 American Home Prod Process for the preparation of 6-aryl-4H-s-triazolo(4,3-a)(1,4)benzodiazepines

Also Published As

Publication number Publication date
EP0227539A1 (fr) 1987-07-01
CA1265794A (fr) 1990-02-13
DE3671451D1 (de) 1990-06-28
JPS62148488A (ja) 1987-07-02
FR2591596B1 (fr) 1988-09-09
FR2591596A1 (fr) 1987-06-19
US4987131A (en) 1991-01-22
EP0227539B1 (fr) 1990-05-23
JPH0788387B2 (ja) 1995-09-27

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