ES2051082T3 - Protesis femoral intramedularmente protesica con funda preformada. - Google Patents

Protesis femoral intramedularmente protesica con funda preformada.

Info

Publication number
ES2051082T3
ES2051082T3 ES91303958T ES91303958T ES2051082T3 ES 2051082 T3 ES2051082 T3 ES 2051082T3 ES 91303958 T ES91303958 T ES 91303958T ES 91303958 T ES91303958 T ES 91303958T ES 2051082 T3 ES2051082 T3 ES 2051082T3
Authority
ES
Spain
Prior art keywords
intramedularly
femoral prosthesis
prosthetic femoral
preformed cover
prosthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91303958T
Other languages
English (en)
Inventor
Jacques Vanderlinden
Peter Lawes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stryker Ireland Ltd
MTG Divestitures LLC
Original Assignee
Howmedica International Inc
Howmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Howmedica International Inc, Howmedica Inc filed Critical Howmedica International Inc
Application granted granted Critical
Publication of ES2051082T3 publication Critical patent/ES2051082T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/36—Femoral heads ; Femoral endoprostheses
    • A61F2/3662—Femoral shafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30721—Accessories
    • A61F2/30724—Spacers for centering an implant in a bone cavity, e.g. in a cement-receiving cavity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30907—Nets or sleeves applied to surface of prostheses or in cement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/36—Femoral heads ; Femoral endoprostheses
    • A61F2/3662—Femoral shafts
    • A61F2/3676—Distal or diaphyseal parts of shafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30565—Special structural features of bone or joint prostheses not otherwise provided for having spring elements
    • A61F2002/30571—Leaf springs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30579—Special structural features of bone or joint prostheses not otherwise provided for with mechanically expandable devices, e.g. fixation devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30907—Nets or sleeves applied to surface of prostheses or in cement
    • A61F2002/30919—Sleeves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2002/4631—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor the prosthesis being specially adapted for being cemented
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00353—Bone cement, e.g. polymethylmethacrylate or PMMA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00952—Coating, pre-coating or prosthesis-covering structure made of bone cement, e.g. pre-applied PMMA cement mantle

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

UNA PROTESIS FEMORAL INTRAMEDULAR PROSTETICA (1) PROVISTA CON UNA FUNDA PREFORMADA SEPARADA (9) HECHA DE MATERIAL ACRILICO QUE TIENE UNAS DIMENSIONES APROPIADAS PARA INCLUIR EL VASTAGO (4) DE LA PROTESIS DESDE LA PUNTA (10) DISTANTE A UNA POSICION EN EL VASTAGO (4) QUE SERA ADYACENTE AL EXTREMO DEL CORTE PROXIMO (6) DEL FEMUR (5) CON EL QUE VA A SER UTILIZADO.
ES91303958T 1990-05-17 1991-05-01 Protesis femoral intramedularmente protesica con funda preformada. Expired - Lifetime ES2051082T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909011132A GB9011132D0 (en) 1990-05-17 1990-05-17 Phosthetic intramedullary femoral prosthesis with preformed sheath

Publications (1)

Publication Number Publication Date
ES2051082T3 true ES2051082T3 (es) 1994-06-01

Family

ID=10676187

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91303958T Expired - Lifetime ES2051082T3 (es) 1990-05-17 1991-05-01 Protesis femoral intramedularmente protesica con funda preformada.

Country Status (12)

Country Link
US (1) US5197990A (es)
EP (1) EP0457464B1 (es)
JP (1) JPH0739558A (es)
AT (1) ATE104129T1 (es)
AU (1) AU642247B2 (es)
CA (1) CA2042642A1 (es)
DE (2) DE69101666T2 (es)
DK (1) DK0457464T3 (es)
ES (1) ES2051082T3 (es)
GB (1) GB9011132D0 (es)
IE (1) IE64392B1 (es)
PT (1) PT97691B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116380A (en) * 1991-02-28 1992-05-26 Zimmer, Inc. Prosthetic implant with spacers having tapered trailing edges
GR1002517B (el) * 1991-09-30 1997-01-23 Johnson & Johnson Orthopaedics Inc. Προσθεση ισχιου.
GB9201734D0 (en) * 1992-01-28 1992-03-11 Howmedica Femoral component for use in a replacement hip prosthesis
GB9202248D0 (en) * 1992-02-03 1992-03-18 Howmedica Prosthesis for attachement without bone cement and method of attaching
US5571193A (en) * 1992-03-12 1996-11-05 Kampner; Stanley L. Implant with reinforced resorbable stem
ATE130748T1 (de) * 1992-04-03 1995-12-15 Sulzer Medizinaltechnik Ag Metallschaft.
US5314493A (en) * 1992-09-10 1994-05-24 Mikhail Michael W E Femoral hip joint prosthesis
IL104313A0 (en) * 1993-01-06 1993-05-13 Bromberg A & Co Ltd Device for fixing a prosthesis to a bone
CA2156740A1 (en) * 1993-03-12 1994-09-15 Robert Poss Bone prosthesis and method of implanting the same
US5443523A (en) * 1994-03-18 1995-08-22 Mikhail; W. E. Michael Femoral stem cement mantle
US5507814A (en) * 1994-03-30 1996-04-16 Northwestern University Orthopedic implant with self-reinforced mantle
US5697932A (en) 1994-11-09 1997-12-16 Osteonics Corp. Bone graft delivery system and method
DE19605735C2 (de) * 1995-12-01 2002-01-10 Dietmar A Kumm Periprothetische Halterungssysteme
DE19613200C2 (de) * 1996-04-02 2001-12-20 Dietmar A Kumm Periprothetische Halterungsysteme für Femurkopf-Endoprothesen
US5871549A (en) * 1996-12-12 1999-02-16 Johnson & Johnson Professional, Inc. Femoral stem with reduced coefficient of friction with respect to bone cement
US5997581A (en) * 1997-12-29 1999-12-07 Johnson & Johnson Professional, Inc. Hip stem cement spacer
US6214053B1 (en) 1998-06-04 2001-04-10 Benoist Girard Sas Prosthesis with centralizer and centralizer for use therewith
GB9812068D0 (en) 1998-06-04 1998-08-05 Benoist Girard & Cie Prosthesis with centraliser and centraliser for use therewith
US6383226B1 (en) 1998-06-09 2002-05-07 The Board Of Trustees Of The Leland Stanford Junior University Prostheses having curvilinear collars
GB9821993D0 (en) * 1998-10-08 1998-12-02 Johnson & Johnson Medical Ltd Centraliser
GB0027893D0 (en) 2000-11-15 2000-12-27 Benoist Girard & Cie Prosthetic implant cement deflector and a set of components to carry out a prosthetic implant employing such a deflector
ITPI20020002A1 (it) * 2002-01-04 2003-07-04 Pierluigi Versari Stelo stabilizzato per protesi
US7534271B2 (en) * 2004-01-22 2009-05-19 Smith + Nephew Femoral hip prosthesis and method of implantation
US20060241759A1 (en) * 2005-04-25 2006-10-26 Sdgi Holdings, Inc. Oriented polymeric spinal implants
US9060820B2 (en) 2005-05-18 2015-06-23 Sonoma Orthopedic Products, Inc. Segmented intramedullary fracture fixation devices and methods
CA2608693A1 (en) * 2005-05-18 2006-11-23 Sonoma Orthopedic Products, Inc. Minimally invasive actuable bone fixation devices, systems and methods of use
US8961516B2 (en) 2005-05-18 2015-02-24 Sonoma Orthopedic Products, Inc. Straight intramedullary fracture fixation devices and methods
NL1032851C2 (nl) * 2006-11-10 2008-05-14 Fondel Finance B V Kit en werkwijze voor het fixeren van een prothese of deel daarvan en/of het vullen van benige defecten.
US20080132896A1 (en) * 2006-11-22 2008-06-05 Sonoma Orthopedic Products, Inc. Curved orthopedic tool
CA2669737A1 (en) * 2006-11-22 2008-05-29 Sonoma Orthopedic Products, Inc. Surgical tools for use in deploying bone repair devices
CA2670263A1 (en) * 2006-11-22 2008-05-29 Sonoma Orthopedic Products, Inc. Fracture fixation device, tools and methods
US20080149115A1 (en) * 2006-11-22 2008-06-26 Sonoma Orthopedic Products, Inc. Surgical station for orthopedic reconstruction surgery
WO2009152273A1 (en) 2008-06-10 2009-12-17 Sonoma Orthopedic Products, Inc. Fracture fixation device, tools and methods
EP2341857A2 (en) 2008-09-26 2011-07-13 Sonoma Orthopedic Products, Inc. Bone fixation device, tools and methods
US9770278B2 (en) 2014-01-17 2017-09-26 Arthrex, Inc. Dual tip guide wire
US9814499B2 (en) 2014-09-30 2017-11-14 Arthrex, Inc. Intramedullary fracture fixation devices and methods

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US4064567A (en) * 1976-09-15 1977-12-27 The Sampson Corporation Prosthesis-to-bone interface system
DE2808740A1 (de) * 1978-03-01 1979-09-06 Omar Pacha Nabil Dr Gelenkprothese
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US4283799A (en) * 1979-09-10 1981-08-18 Massachusetts Institute Of Technology Pre-coated body implant
GB2104391B (en) * 1981-08-25 1984-12-19 Univ Exeter Spacer for intra-medullary implant
US4919665A (en) * 1982-04-19 1990-04-24 Homsy Charles A Implantation of articulating joint prosthesis
DE3334058C2 (de) * 1983-09-21 1985-07-25 Ulrich Dr.-Ing. 5600 Wuppertal Witzel Oberschenkelteil für eine Hüftgelenkendoprothese
GB8401059D0 (en) * 1984-01-16 1984-02-15 Exeter University Of Fixation of implants in bone
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GB2162753A (en) * 1984-06-22 1986-02-12 Thackray C F Ltd Sleeve for metal implant into bone
GB8426866D0 (en) * 1984-10-24 1984-11-28 Finsbury Instr Ltd Bone implants
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US4735625A (en) * 1985-09-11 1988-04-05 Richards Medical Company Bone cement reinforcement and method
US4728335A (en) * 1986-12-15 1988-03-01 Jurgutis John A Hip prosthesis
FR2610515A1 (fr) * 1987-02-09 1988-08-12 Jean Lannelongue Prothese d'epaule
US4888023B1 (en) * 1988-01-19 1996-01-23 Osteonics Corp Femoral prosthesis with uncoupled distal tip
DE3802214A1 (de) * 1988-01-26 1989-07-27 Roland Man Druckmasch Zwischenstueck zur verankerung eines prothesenteiles in einem knochen
GB8924985D0 (en) * 1989-11-06 1989-12-28 Howmedica Centaliser for the stem of an intramedullary prosthesis
US5080680A (en) * 1990-09-04 1992-01-14 Mikhail Michael W E Femoral stem prosthesis with preapplied cement mantle

Also Published As

Publication number Publication date
DE69101666D1 (de) 1994-05-19
US5197990A (en) 1993-03-30
EP0457464A1 (en) 1991-11-21
AU642247B2 (en) 1993-10-14
AU7645491A (en) 1991-11-21
DE9105872U1 (es) 1991-07-18
IE911491A1 (en) 1991-11-20
CA2042642A1 (en) 1991-11-18
IE64392B1 (en) 1995-08-09
ATE104129T1 (de) 1994-04-15
JPH0739558A (ja) 1995-02-10
EP0457464B1 (en) 1994-04-13
DE69101666T2 (de) 1994-07-28
DK0457464T3 (da) 1994-06-27
GB9011132D0 (en) 1990-07-04
PT97691A (pt) 1993-07-30
PT97691B (pt) 1998-12-31

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