ES2046214T3 - Medicamento con liberacion retardada de la sustancia activa. - Google Patents

Medicamento con liberacion retardada de la sustancia activa.

Info

Publication number
ES2046214T3
ES2046214T3 ES198787810672T ES87810672T ES2046214T3 ES 2046214 T3 ES2046214 T3 ES 2046214T3 ES 198787810672 T ES198787810672 T ES 198787810672T ES 87810672 T ES87810672 T ES 87810672T ES 2046214 T3 ES2046214 T3 ES 2046214T3
Authority
ES
Spain
Prior art keywords
hlb value
active ingredient
water
medication
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787810672T
Other languages
English (en)
Inventor
Pawan Seth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mepha GmbH
Original Assignee
Mepha GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mepha GmbH filed Critical Mepha GmbH
Application granted granted Critical
Publication of ES2046214T3 publication Critical patent/ES2046214T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

ADEMAS DE LA SUSTANCIA ACTIVA LAS CAPSULAS CONTIENEN UN TENSIDO NO IONICO QUE CONSTA DE UN ESTER O ETER POLIGLICOL Y CONTIENE COMPONENTES HIDROFILOS Y LIPOFILOS Y UN POLIMERO ORGANICO QUE PUEDE FORMARSE CON LA SUSTANCIA ACTIVA Y EL TENSIDO UNA MASA LIBREMENTE FLUIBLE. ESENCIALMENTE PARA EL RETARDO DE LA LIBERACION SE SINCRONIZA LA SOLUBILIDAD EN AGUA DE LA SUSTANCIA ACTIVA Y EL CARACTER HIDROFILO/LIPOFILO (HLB - VALOR) DEL TENSIDO. INSOLUBLE EN AGUA, VALOR HLB SOBRE 16; SOLUBLE MODERADAMENTE, VALOR HLB ENTRE 10 Y 16; SOLUBLE EN AGUA, VALOR HLB BAJO 10.
ES198787810672T 1987-02-02 1987-11-16 Medicamento con liberacion retardada de la sustancia activa. Expired - Lifetime ES2046214T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH355/87A CH668553A5 (de) 1987-02-02 1987-02-02 Arzneimittel mit verzoegerter wirkstofffreisetzung.

Publications (1)

Publication Number Publication Date
ES2046214T3 true ES2046214T3 (es) 1994-02-01

Family

ID=4185132

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787810672T Expired - Lifetime ES2046214T3 (es) 1987-02-02 1987-11-16 Medicamento con liberacion retardada de la sustancia activa.

Country Status (7)

Country Link
US (1) US4795643A (es)
EP (1) EP0277459B1 (es)
JP (1) JP2559785B2 (es)
AT (1) ATE87824T1 (es)
CH (1) CH668553A5 (es)
DE (1) DE3785330D1 (es)
ES (1) ES2046214T3 (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5069911A (en) * 1985-02-05 1991-12-03 Sandoz Ltd. Pharmaceutical 9,10-dihydrogenated ergot alkaloid containing compositions
GB8701332D0 (en) * 1987-01-21 1987-02-25 Lilly Industries Ltd Capsule filling
DE3702029A1 (de) * 1987-01-24 1988-08-04 Basf Ag Waessriges oder pulverfoermiges, wasserdispergierbares praeparat eines in wasser schwerloeslichen pharmazeutischen wirkstoffs und verfahren zu seiner herstellung
DE3714402A1 (de) * 1987-04-30 1988-11-10 Kali Chemie Pharma Gmbh Arzneimittelformulierung
US4981852A (en) * 1988-05-13 1991-01-01 Multilan Ag Chemical compounds triamterene and hydrochlorothiazide
JP3121080B2 (ja) * 1991-12-19 2000-12-25 アール・ピー・シーラー コーポレイション カプセル封入用溶液
US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
KR950702436A (ko) * 1992-07-28 1995-07-29 자코부스 코르넬리스 라세르 가교 결합 양이온성 중합체 및 알콜실화 에테르를 함유하는 국소용 약학 조성물(pharmaceutical composition for topical use containing a crosslinked cationic polymer and an alkoxylated ether)
DE29502547U1 (de) * 1995-02-16 1995-03-30 Roehm Gmbh Thermoplastisches Überzugs- und Bindemittel für Arzneiformen
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
US20030153623A1 (en) * 1998-07-22 2003-08-14 Yamanouchi Pharmaceutical Co., Ltd. Solid preparation containing sparingly soluble NSAIDs
US6387381B2 (en) * 1998-09-24 2002-05-14 Ez-Med Company Semi-moist oral delivery system
US7838032B2 (en) * 2000-04-28 2010-11-23 Reckitt Benckiser Inc. Sustained release of guaifenesin
US6955821B2 (en) * 2000-04-28 2005-10-18 Adams Laboratories, Inc. Sustained release formulations of guaifenesin and additional drug ingredients
US7985420B2 (en) * 2000-04-28 2011-07-26 Reckitt Benckiser Inc. Sustained release of guaifenesin combination drugs
US6372252B1 (en) 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
US8012504B2 (en) * 2000-04-28 2011-09-06 Reckitt Benckiser Inc. Sustained release of guaifenesin combination drugs
US6740333B2 (en) * 2000-07-07 2004-05-25 Anestic Aps Suppository and composition comprising at least one polyethylene glycol
SK288049B6 (sk) * 2001-02-27 2013-03-01 Evonik Rohm Gmbh Coating and binding agent, its use for production of cover oral or dermal pharmaceutical dosage forms, process for its production and dosage form containing same
US20030091634A1 (en) * 2001-09-14 2003-05-15 Pawan Seth Delayed release tablet of venlafaxin
US20030118647A1 (en) * 2001-12-04 2003-06-26 Pawan Seth Extended release tablet of metformin
KR20030060730A (ko) * 2002-01-09 2003-07-16 하나제약 주식회사 난용성 약물의 서방화 제제 조성물
DE10208344A1 (de) * 2002-02-27 2003-09-04 Roehm Gmbh Schmelzextrusion von Wirkstoffsalzen
US20040086567A1 (en) * 2002-10-30 2004-05-06 Pawan Seth Bioequivalent composition of itraconazole and a hydrophilic polymer
US20040162320A1 (en) * 2003-02-14 2004-08-19 Pawan Seth Solid composition containing nisoldipine a mixture of polyethylene oxides and an antioxidant
US20060153909A1 (en) * 2003-06-27 2006-07-13 Soko Motoune Hard capsule
PL196544B1 (pl) * 2003-08-08 2008-01-31 Biovail Lab Int Srl Tabletka o zmodyfikowanym uwalnianiu
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
AU2005325213B2 (en) * 2004-08-04 2010-10-07 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
US20060078616A1 (en) * 2004-08-30 2006-04-13 Georgewill Dawaye A Thermoreversible pharmaceutical formulation for anti-microbial agents comprising poloxamer polymers and hydroxy fatty acid ester of polyethylene glycol
US7318920B2 (en) * 2004-09-27 2008-01-15 Ez-Med Company Low water activity nutritional product having beneficial microbial and high oil content
CA3014633C (en) 2007-10-08 2022-05-17 Aurinia Pharmaceuticals Inc. Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors
EP2222281B1 (en) 2007-12-20 2018-12-05 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
CA2730760A1 (en) * 2008-07-16 2010-01-21 Surmodics Pharmaceuticals, Inc. Process for preparing microparticles containing bioactive peptides
CA2764635C (en) * 2009-06-09 2018-05-22 Lux Biosciences, Inc. Topical drug delivery systems for ophthalmic use
CA2775077C (en) * 2009-09-22 2018-05-01 Evonik Degussa Corporation Implant devices having varying bioactive agent loading configurations
US20130071444A1 (en) 2011-09-16 2013-03-21 The Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Healthcare System Amphiphilic Cationic Polymers and Methods of Use Thereof
WO2014048507A1 (en) 2012-09-28 2014-04-03 Evonik Industries Ag Process for preparing aqueous dispersions
EP2922907A1 (en) 2012-11-22 2015-09-30 Evonik Röhm GmbH Process for preparing a granulated product from a powder composition
CA3001337C (en) 2015-10-09 2023-12-12 Reckitt Benckiser Llc Pharmaceutical formulation
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990333A (en) * 1959-06-29 1961-06-27 Upjohn Co Gelatin capsule with nu-alkyl amide, for aqueous vehicles
NL148500B (nl) * 1967-10-07 1976-02-16 Scherer Gmbh R P Depotgeneesmiddelen in capsulevorm.
US3932634A (en) * 1973-06-28 1976-01-13 Pfizer Inc. High potency vitamin water dispersible formulations
GB1572226A (en) * 1977-11-03 1980-07-30 Hoechst Uk Ltd Pharmaceutical preparations in solid unit dosage form
JPS5495721A (en) * 1978-01-11 1979-07-28 Nippon Kayaku Co Ltd Nifedipine preparation
US4539199A (en) * 1981-01-14 1985-09-03 Egyt Gyogyszervegyeszeti Gyar Sustained release pharmaceutical compositions
US4428927A (en) * 1981-05-11 1984-01-31 R. P. Scherer Corporation Masticatory soft elastic gelatin capsules and method for the manufacture thereof
US4486412A (en) * 1983-03-15 1984-12-04 Pharmacaps, Inc. Encapsulated antacid dispersions
US4663149A (en) * 1984-03-21 1987-05-05 Alza Corporation Dispenser comprising inner and outer walls functioning as cooperative unit
SE8401856D0 (sv) * 1984-04-04 1984-04-04 Draco Ab New pharmaceutical preparations
US4681765A (en) * 1984-09-13 1987-07-21 American Home Products Corporation Rapid releasing triamterene containing gelatin capsule dosage forms for once daily antihypertensive use
IT1191608B (it) * 1985-02-01 1988-03-23 Zambon Spa Composizione farmaceutica e forme farmaceutiche che la contengono

Also Published As

Publication number Publication date
JP2559785B2 (ja) 1996-12-04
ATE87824T1 (de) 1993-04-15
EP0277459A2 (de) 1988-08-10
EP0277459B1 (de) 1993-04-07
DE3785330D1 (de) 1993-05-13
JPS63196512A (ja) 1988-08-15
US4795643A (en) 1989-01-03
CH668553A5 (de) 1989-01-13
EP0277459A3 (en) 1990-12-05

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