ES2043798T3 - Un metodo para preparar las prostaglandinas e. - Google Patents
Un metodo para preparar las prostaglandinas e.Info
- Publication number
- ES2043798T3 ES2043798T3 ES88300709T ES88300709T ES2043798T3 ES 2043798 T3 ES2043798 T3 ES 2043798T3 ES 88300709 T ES88300709 T ES 88300709T ES 88300709 T ES88300709 T ES 88300709T ES 2043798 T3 ES2043798 T3 ES 2043798T3
- Authority
- ES
- Spain
- Prior art keywords
- ceto
- prostaglandin
- dihydro
- advantage
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 208000025865 Ulcer Diseases 0.000 abstract 2
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 231100000397 ulcer Toxicity 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 230000002183 duodenal effect Effects 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA NUEVA PROSTAGLANDINA E 13,14 DIHIDRO 15-CETO DE ESTA INVENCION TIENE EFECTOS PREVENTIVOS CONTRA LAS ULCERAS. ADEMAS LA NUEVA PROSTAGLANDINA E 13,14 DIHIDRO 15-CETO TIENE UNA VENTAJA QUE TIENE UNA VENTAJA YA QUE NO TIENE LOS EFECTOS COLATERALES QUE TIENE INTRINSECAMENTE LA PROSTAGLANDINA E, O QUE PUEDE EDUCIR NOTABLEMENTE LOS EFECTOS DE LA PROSTAGLANDINA E. POR CINSIGUIENTE LA NUEVA 13,14-DIHIDRO-15-CETO PROSTAGLANDINAS E DE ESTA INVENCION SON EFECTIVAS PARA EL USO EN EL TRATAMIENTO Y PREVENCION DE ULCERAS COMO SON LA ULCERA DUODENAL Y GASTRICA TANTO DE ANIMALES COMO DE HUMANOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1882087 | 1987-01-28 | ||
JP6535287 | 1987-03-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2043798T3 true ES2043798T3 (es) | 1994-01-01 |
Family
ID=26355556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88300709T Expired - Lifetime ES2043798T3 (es) | 1987-01-28 | 1988-01-28 | Un metodo para preparar las prostaglandinas e. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0284180B1 (es) |
KR (1) | KR930006192B1 (es) |
CA (1) | CA1323364C (es) |
DE (1) | DE3873797T2 (es) |
ES (1) | ES2043798T3 (es) |
GR (1) | GR3005677T3 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1324129C (en) * | 1987-04-30 | 1993-11-09 | Ryuzo Ueno | Prostaglandins of the f series |
US6420422B1 (en) | 1987-09-18 | 2002-07-16 | Sucampo Pharmaceuticals, Inc. | Ocular hypotensive agents |
ES2052735T3 (es) * | 1987-09-18 | 1994-07-16 | R Tech Ueno Ltd | Un metodo para producir un agente hipotensor ocular. |
US5236907A (en) * | 1988-10-01 | 1993-08-17 | R-Tech Ueno Ltd. | Ocular hypotensive agents |
JP2597629B2 (ja) | 1988-02-26 | 1997-04-09 | 株式会社 上野製薬応用研究所 | 13,14−ジヒドロ−15−ケトプロスタグランジン類の安定化 |
DE69019431T2 (de) * | 1989-07-27 | 1995-09-14 | Ueno Seiyaku Oyo Kenkyujo Kk | Verwendung von 15-Keto-Prostansäure-Derivaten zur Herstellung eines Medikaments für die Verbesserung der Ausscheidung des Kaliumions. |
US5234954A (en) * | 1989-07-27 | 1993-08-10 | K.K. Ueno Seiyaku Oyo Kenkyujo | Treatment of hyperlipidemia with 15-keto-prostaglandin compounds |
DE69018903T2 (de) * | 1989-08-09 | 1995-08-24 | Ueno Seiyaku Oyo Kenkyujo Kk | Verwendung von Prostansäurederivaten zur Herstellung von Arzneimitteln zur Verbesserung der Ausscheidung von Nichtprotein in die Därme. |
CA2027814C (en) * | 1989-10-20 | 1996-07-30 | Ryuji Ueno | Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds |
CA2030345C (en) * | 1989-11-22 | 1998-12-08 | Ryuji Ueno | Use of 15-keto-prostaglandin compound for improvement of encephalic function |
US5254588A (en) * | 1989-11-22 | 1993-10-19 | Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo | Treatment of pulmonary dysfunction with 15-ketoprostaglandin compounds |
US5256696A (en) * | 1989-11-22 | 1993-10-26 | Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo | Treatment of cardiac dysfunction with 15-ketoprostaglandin compounds |
CA2039420C (en) * | 1990-04-04 | 1996-12-10 | Ryuji Ueno | Treatment of cataract with 15-keto-prostaglandin compounds |
CA2046069C (en) * | 1990-07-10 | 2002-04-09 | Ryuji Ueno | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds |
ES2093774T3 (es) * | 1991-03-14 | 1997-01-01 | R Tech Ueno Ltd | Estimulacion de la curacion de heridas con un compuesto 15-cetoprostaglandina. |
CA2150287C (en) | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
AU739343B2 (en) * | 1997-11-28 | 2001-10-11 | Sucampo Ag | Endothelin antagonist |
US6410802B1 (en) | 1999-04-01 | 2002-06-25 | Esperion Therapeutics, Inc. | Methods for synthesizing ether compounds and intermediates therefor |
TWI263505B (en) | 2001-11-19 | 2006-10-11 | Sucampo Ag | Pharmaceutical composition comprising a C1C-2 channel opener |
US20060281818A1 (en) * | 2005-03-21 | 2006-12-14 | Sucampo Ag, North Carolina State University | Method for treating mucosal disorders |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3836578A (en) * | 1965-12-16 | 1974-09-17 | Kemiska Inst | Prostanoic acid derivatives |
GB1476661A (en) * | 1974-05-13 | 1977-06-16 | American Cyanamid Co | Prostaglandins |
-
1988
- 1988-01-26 CA CA000557407A patent/CA1323364C/en not_active Expired - Lifetime
- 1988-01-28 ES ES88300709T patent/ES2043798T3/es not_active Expired - Lifetime
- 1988-01-28 KR KR1019880000702A patent/KR930006192B1/ko not_active IP Right Cessation
- 1988-01-28 DE DE8888300709T patent/DE3873797T2/de not_active Expired - Lifetime
- 1988-01-28 EP EP88300709A patent/EP0284180B1/en not_active Expired - Lifetime
-
1992
- 1992-09-10 GR GR920402003T patent/GR3005677T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
KR880008985A (ko) | 1988-09-13 |
DE3873797T2 (de) | 1993-01-21 |
GR3005677T3 (es) | 1993-06-07 |
EP0284180B1 (en) | 1992-08-19 |
DE3873797D1 (de) | 1992-09-24 |
CA1323364C (en) | 1993-10-19 |
KR930006192B1 (ko) | 1993-07-08 |
EP0284180A1 (en) | 1988-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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