ES2043798T3 - Un metodo para preparar las prostaglandinas e. - Google Patents

Un metodo para preparar las prostaglandinas e.

Info

Publication number
ES2043798T3
ES2043798T3 ES88300709T ES88300709T ES2043798T3 ES 2043798 T3 ES2043798 T3 ES 2043798T3 ES 88300709 T ES88300709 T ES 88300709T ES 88300709 T ES88300709 T ES 88300709T ES 2043798 T3 ES2043798 T3 ES 2043798T3
Authority
ES
Spain
Prior art keywords
ceto
prostaglandin
dihydro
advantage
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88300709T
Other languages
English (en)
Inventor
Ryuzo Ueno
Ryuji Ueno
Ichie Kato
Tomio Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ueno Seiyaku Oyo Kenkyujo KK
R Tech Ueno Ltd
Original Assignee
Ueno Seiyaku Oyo Kenkyujo KK
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ueno Seiyaku Oyo Kenkyujo KK, R Tech Ueno Ltd filed Critical Ueno Seiyaku Oyo Kenkyujo KK
Application granted granted Critical
Publication of ES2043798T3 publication Critical patent/ES2043798T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA NUEVA PROSTAGLANDINA E 13,14 DIHIDRO 15-CETO DE ESTA INVENCION TIENE EFECTOS PREVENTIVOS CONTRA LAS ULCERAS. ADEMAS LA NUEVA PROSTAGLANDINA E 13,14 DIHIDRO 15-CETO TIENE UNA VENTAJA QUE TIENE UNA VENTAJA YA QUE NO TIENE LOS EFECTOS COLATERALES QUE TIENE INTRINSECAMENTE LA PROSTAGLANDINA E, O QUE PUEDE EDUCIR NOTABLEMENTE LOS EFECTOS DE LA PROSTAGLANDINA E. POR CINSIGUIENTE LA NUEVA 13,14-DIHIDRO-15-CETO PROSTAGLANDINAS E DE ESTA INVENCION SON EFECTIVAS PARA EL USO EN EL TRATAMIENTO Y PREVENCION DE ULCERAS COMO SON LA ULCERA DUODENAL Y GASTRICA TANTO DE ANIMALES COMO DE HUMANOS.
ES88300709T 1987-01-28 1988-01-28 Un metodo para preparar las prostaglandinas e. Expired - Lifetime ES2043798T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1882087 1987-01-28
JP6535287 1987-03-18

Publications (1)

Publication Number Publication Date
ES2043798T3 true ES2043798T3 (es) 1994-01-01

Family

ID=26355556

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88300709T Expired - Lifetime ES2043798T3 (es) 1987-01-28 1988-01-28 Un metodo para preparar las prostaglandinas e.

Country Status (6)

Country Link
EP (1) EP0284180B1 (es)
KR (1) KR930006192B1 (es)
CA (1) CA1323364C (es)
DE (1) DE3873797T2 (es)
ES (1) ES2043798T3 (es)
GR (1) GR3005677T3 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
US6420422B1 (en) 1987-09-18 2002-07-16 Sucampo Pharmaceuticals, Inc. Ocular hypotensive agents
ES2052735T3 (es) * 1987-09-18 1994-07-16 R Tech Ueno Ltd Un metodo para producir un agente hipotensor ocular.
US5236907A (en) * 1988-10-01 1993-08-17 R-Tech Ueno Ltd. Ocular hypotensive agents
JP2597629B2 (ja) 1988-02-26 1997-04-09 株式会社 上野製薬応用研究所 13,14−ジヒドロ−15−ケトプロスタグランジン類の安定化
DE69019431T2 (de) * 1989-07-27 1995-09-14 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von 15-Keto-Prostansäure-Derivaten zur Herstellung eines Medikaments für die Verbesserung der Ausscheidung des Kaliumions.
US5234954A (en) * 1989-07-27 1993-08-10 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hyperlipidemia with 15-keto-prostaglandin compounds
DE69018903T2 (de) * 1989-08-09 1995-08-24 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von Prostansäurederivaten zur Herstellung von Arzneimitteln zur Verbesserung der Ausscheidung von Nichtprotein in die Därme.
CA2027814C (en) * 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
CA2030345C (en) * 1989-11-22 1998-12-08 Ryuji Ueno Use of 15-keto-prostaglandin compound for improvement of encephalic function
US5254588A (en) * 1989-11-22 1993-10-19 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of pulmonary dysfunction with 15-ketoprostaglandin compounds
US5256696A (en) * 1989-11-22 1993-10-26 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of cardiac dysfunction with 15-ketoprostaglandin compounds
CA2039420C (en) * 1990-04-04 1996-12-10 Ryuji Ueno Treatment of cataract with 15-keto-prostaglandin compounds
CA2046069C (en) * 1990-07-10 2002-04-09 Ryuji Ueno Treatment of inflammatory diseases with 15-keto-prostaglandin compounds
ES2093774T3 (es) * 1991-03-14 1997-01-01 R Tech Ueno Ltd Estimulacion de la curacion de heridas con un compuesto 15-cetoprostaglandina.
CA2150287C (en) 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
AU739343B2 (en) * 1997-11-28 2001-10-11 Sucampo Ag Endothelin antagonist
US6410802B1 (en) 1999-04-01 2002-06-25 Esperion Therapeutics, Inc. Methods for synthesizing ether compounds and intermediates therefor
TWI263505B (en) 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3836578A (en) * 1965-12-16 1974-09-17 Kemiska Inst Prostanoic acid derivatives
GB1476661A (en) * 1974-05-13 1977-06-16 American Cyanamid Co Prostaglandins

Also Published As

Publication number Publication date
KR880008985A (ko) 1988-09-13
DE3873797T2 (de) 1993-01-21
GR3005677T3 (es) 1993-06-07
EP0284180B1 (en) 1992-08-19
DE3873797D1 (de) 1992-09-24
CA1323364C (en) 1993-10-19
KR930006192B1 (ko) 1993-07-08
EP0284180A1 (en) 1988-09-28

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