ES2042883T3 - Tabletas de cimetidina dispersables. - Google Patents

Tabletas de cimetidina dispersables.

Info

Publication number
ES2042883T3
ES2042883T3 ES89110951T ES89110951T ES2042883T3 ES 2042883 T3 ES2042883 T3 ES 2042883T3 ES 89110951 T ES89110951 T ES 89110951T ES 89110951 T ES89110951 T ES 89110951T ES 2042883 T3 ES2042883 T3 ES 2042883T3
Authority
ES
Spain
Prior art keywords
tablets
dispersible
cimetidine
weight
tablets containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89110951T
Other languages
English (en)
Inventor
Mateja Kovacic
Jenny Milovac
Polona Cvelbar
Anton Stalc
Zvezdana Trost
Zdravko Kopitar
Bojan Kofler
Vida Nikolic
Marija Lampret
Marija Lippai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lek Pharmaceuticals dd
Original Assignee
Lek Pharmaceuticals and Chemical Co dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals and Chemical Co dd filed Critical Lek Pharmaceuticals and Chemical Co dd
Application granted granted Critical
Publication of ES2042883T3 publication Critical patent/ES2042883T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN UNAS NUEVAS TABLETAS DE CIMETIDINA DISPERSABLE QUE CONTIENE DE UN 30 A UN 90% DE PESO DE UNA DE LAS MODIFICACIONES POLIMORFAS DE CIMETIDINA A,B O C, DE UN 5 A UN 55% DE PESO DE UNO O MAS AGENTES DESINTEGRADORES, DE UN 0,05 A UN 5,0% DE PESO DE UN SULFACTANTE, TAL Y COMO SULFATO LAURICOSODICO JUNTO CON OTROS PORTADORES COMUNES. EL PROCESO PARA LA FABRICACION DE LAS TABLETAS DE CIMETIDINA DISPERSABLE SE EFECTUA SOBRE LA BASE DE CONOCIDOS METODOS PARA LA GRANULACION DE LOS INGREDIENTES Y LA COMPRESION DEL GRANULADO PARA HACER LAS TABLETAS. LAS TABLETAS DISPERSABLES SE DESINTEGRAN CUANDO ENTRAN EN CONTACTO CON AGUA A TEMPERATURA AMBIENTE EN MENOS DE UN MINUTO PRODUCIENDO UNA FINA DISPERSION, LO QUE FACILITA LA ADMINISTRACION ORAL. POR ELLO ESTAS TABLETAS SON ADECUADAS PARTICULARMENTE PARA CIERTOS GRUPOS DE PACIENTES, ESPECIALMENTE PARA ANCIANOS Y NIÑOS. LAS TABLETAS DISPERSABLES CONTENIENDO CIMETIDINA SOBRESALEN POR SU MEJORADA VELOCIDAD DE DISOLUCION Y BUEN BIOAPROVECHAMIENTO.
ES89110951T 1988-06-23 1989-06-16 Tabletas de cimetidina dispersables. Expired - Lifetime ES2042883T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU01209/88A YU120988A (en) 1988-06-23 1988-06-23 Process for preparing new dispersion pills of cimetidine

Publications (1)

Publication Number Publication Date
ES2042883T3 true ES2042883T3 (es) 1993-12-16

Family

ID=25553226

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89110951T Expired - Lifetime ES2042883T3 (es) 1988-06-23 1989-06-16 Tabletas de cimetidina dispersables.

Country Status (9)

Country Link
US (1) US5069910A (es)
EP (1) EP0347767B1 (es)
JP (1) JPH0791182B2 (es)
KR (1) KR910000126A (es)
AT (1) ATE80298T1 (es)
CA (1) CA1333156C (es)
DE (1) DE68902782T2 (es)
ES (1) ES2042883T3 (es)
YU (1) YU120988A (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282071B6 (sk) * 1991-01-30 2001-10-08 The Wellcome Foundation Limited Tableta dispergovateľná vo vode a spôsob jej prípravy
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
TW284688B (es) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
US5609883A (en) * 1994-09-16 1997-03-11 Advanced Technology Pharmaceuticals Corporation Compressed tablet transitory lubricant system
US5807577A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US5807578A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
US6129932A (en) * 1997-09-05 2000-10-10 Merck & Co., Inc. Compositions for inhibiting platelet aggregation
IN187039B (es) * 1997-12-08 2001-12-29 Council Scient Ind Res
US6287693B1 (en) 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
US6515008B1 (en) * 2000-05-04 2003-02-04 Smithkline Beecham Corporation Formulation
US20030113366A1 (en) * 2001-12-14 2003-06-19 Macgregor Alexander Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents
EP1490031A1 (en) * 2002-03-07 2004-12-29 Vectura Limited Fast melt multiparticulate formulations for oral delivery
GB0209265D0 (en) * 2002-04-23 2002-06-05 Novartis Ag Organic compounds
GB0223978D0 (en) * 2002-10-15 2002-11-20 Novartis Ag Organic compound
US20120071409A1 (en) * 2007-04-18 2012-03-22 Hack Jacob C Colloidal Liposomal Compositions and Methods
JP5470022B2 (ja) * 2008-12-25 2014-04-16 ライオン株式会社 高嵩密度粒状洗剤組成物
EP2845850A1 (en) 2013-09-10 2015-03-11 ObsEva S.A. Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
EP2886107A1 (en) * 2013-12-17 2015-06-24 ObsEva S.A. Oral formulations of pyrrolydine derivatives
CA2953722C (en) 2014-07-02 2022-09-13 ObsEva SA Crystalline (3z,5s)-5-(hydroxymethyl)-1-[(2'-methyl-1,1'-biphenyl-4-yl)carbonyl]pyrrolidin-3-one o-methyloxime, and methods of using the same
WO2016133551A1 (en) 2015-02-18 2016-08-25 Inductotherm Corp. Electric induction melting and holding furnaces for reactive metals and alloys
CN112394134B (zh) * 2019-08-14 2022-11-22 江苏晶立信医药科技有限公司 西咪替丁原料药的有关物质的检测方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035770A1 (en) * 1969-03-14 1970-12-24 Orsymonde Antispasmodic quercetin comp having - long lasting activity
JPS504231A (es) * 1973-05-11 1975-01-17
JPS56164122A (en) * 1980-05-21 1981-12-17 Fujimoto Seiyaku Kk Drug composition comprising cimetidine as main agent
US4764380A (en) * 1982-03-22 1988-08-16 Alza Corporation Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills
CA1239349A (en) * 1983-10-10 1988-07-19 Eberhard F. Gottwald Pharmaceutical composition containing cimetidine
JPS60100515A (ja) * 1983-11-05 1985-06-04 Dai Ichi Kogyo Seiyaku Co Ltd セルロ−ス錠剤成型物の製造方法
US4851228A (en) * 1984-06-20 1989-07-25 Merck & Co., Inc. Multiparticulate controlled porosity osmotic
CA1229552A (en) * 1984-07-09 1987-11-24 Audley A. Legore Cimetidine compositions
US4693895A (en) * 1984-10-26 1987-09-15 Alza Corporation Colon delivery system
FR2593065B1 (fr) * 1986-01-22 1988-09-09 Smith Kline French Lab Couples effervescents, compositions effervescentes d'antagonistes h2 de l'histamine les contenant et leur preparation.
AT384736B (de) * 1986-09-26 1987-12-28 Kwizda Fa F Johann Verfahren zur herstellung galenischer zubereitungen
US4853229A (en) * 1987-10-26 1989-08-01 Alza Corporation Method for adminstering tiny pills

Also Published As

Publication number Publication date
EP0347767A1 (en) 1989-12-27
YU120988A (en) 1990-06-30
JPH0791182B2 (ja) 1995-10-04
DE68902782D1 (de) 1992-10-15
US5069910A (en) 1991-12-03
DE68902782T2 (de) 1993-04-01
JPH0245416A (ja) 1990-02-15
EP0347767B1 (en) 1992-09-09
ATE80298T1 (de) 1992-09-15
KR910000126A (ko) 1991-01-29
CA1333156C (en) 1994-11-22

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