ES2041791T3 - Mejoras en o relativas a antagonistas de leucotrienos. - Google Patents

Mejoras en o relativas a antagonistas de leucotrienos.

Info

Publication number
ES2041791T3
ES2041791T3 ES198888303179T ES88303179T ES2041791T3 ES 2041791 T3 ES2041791 T3 ES 2041791T3 ES 198888303179 T ES198888303179 T ES 198888303179T ES 88303179 T ES88303179 T ES 88303179T ES 2041791 T3 ES2041791 T3 ES 2041791T3
Authority
ES
Spain
Prior art keywords
relative
antagonists
leucotrene
leucotrene antagonists
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888303179T
Other languages
English (en)
Inventor
Robert Delane Dillard
Doris Elfriede Mccullough
Francis Patrick Carr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2041791T3 publication Critical patent/ES2041791T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/337—Polycyclic acids with carboxyl groups bound to condensed ring systems
    • C07C63/34—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings
    • C07C63/36—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings containing one carboxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

ESTA INVENCION PROPORCIONA DERIVADOS BENCENICOS QUE SON ANTAGONISTAS DE LEUCOTRIENO, FORMULACIONES QUE CONTIENEN ESTOS DERIVADOS EN EL TRATAMIENTO DE CONDICIONES CARACETRIZADAS POR UNA LIBERACION EXCESIVA DE LEUCOTRIENOS.
ES198888303179T 1987-04-10 1988-04-08 Mejoras en o relativas a antagonistas de leucotrienos. Expired - Lifetime ES2041791T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/037,284 US4874777A (en) 1987-04-10 1987-04-10 Leukotriene antagonists

Publications (1)

Publication Number Publication Date
ES2041791T3 true ES2041791T3 (es) 1993-12-01

Family

ID=21893507

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888303179T Expired - Lifetime ES2041791T3 (es) 1987-04-10 1988-04-08 Mejoras en o relativas a antagonistas de leucotrienos.

Country Status (20)

Country Link
US (1) US4874777A (es)
EP (1) EP0288190B1 (es)
JP (1) JPS63277642A (es)
KR (1) KR880012520A (es)
CN (1) CN88101939A (es)
AT (1) ATE78023T1 (es)
AU (1) AU608311B2 (es)
CA (1) CA1327588C (es)
DE (1) DE3872576T2 (es)
DK (1) DK188388A (es)
EG (1) EG18480A (es)
ES (1) ES2041791T3 (es)
GR (1) GR3005836T3 (es)
HU (1) HU203517B (es)
IE (1) IE61277B1 (es)
NZ (1) NZ224137A (es)
PH (1) PH25349A (es)
PT (1) PT87180B (es)
SU (1) SU1731042A3 (es)
ZA (1) ZA882420B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853398A (en) * 1987-04-13 1989-08-01 Eli Lilly And Company Leukotriene antagonists and use thereas
ZA894913B (en) * 1988-07-12 1990-03-28 Ici Pharma Heterocyclic compounds
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
HU230352B1 (hu) 2001-06-12 2016-02-29 Wellstat Therapeutics Corporation Metabolikus rendellenességek kezelésére adható vegyületek és ezeket tartalmazó gyógyászati készítmények
RU2522458C2 (ru) * 2008-04-30 2014-07-10 Веллстат Терапьютикс Корпорейшн Тетразольные соединения для снижения концентрации мочевой кислоты

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU469247A3 (ru) * 1972-01-14 1975-04-30 Майлз Лабораториз Инк (Фирма) Способ получени производных хромона
DE3070912D1 (en) * 1979-03-20 1985-09-05 Fisons Plc Pharmaceutical heterocyclic compounds, processes for their preparation and compositions containing them
ATE7897T1 (de) * 1979-09-05 1984-06-15 Glaxo Group Limited Phenol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
EP0056172B1 (en) * 1981-01-09 1985-04-03 FISONS plc Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
EP0061800B1 (en) * 1981-03-24 1985-08-28 FISONS plc Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them
US4474788A (en) * 1981-11-12 1984-10-02 Fisons Plc Anti-SRSA quinoline carboxylic acid derivatives
IE54269B1 (en) * 1981-12-30 1989-08-02 Ici America Inc Pharmaceutically active phenylcarboxylic acid derivatives
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
ZA844519B (en) * 1983-06-24 1985-02-27 Hoffmann La Roche Dihydrobenzopyran derivatives
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
US4644071A (en) * 1984-07-11 1987-02-17 G. D. Searle & Co. Aralkoxy and aryloxyalkoxy kojic acid derivatives
US4617407A (en) * 1984-08-30 1986-10-14 Merck Frosst Canada, Inc. Leukotriene antagonists
US4567279A (en) * 1984-12-13 1986-01-28 Usv Pharmaceutical Corp. Diarylhydroxy alkanones and alkenones antiallergy agents
US4628115A (en) * 1985-03-25 1986-12-09 Hoffmann-La Roche Inc. Substituted 4-acetyl-3-hydroxyphenoxy alkanoic acids
PT85110A (en) * 1986-06-23 1987-07-01 Merck Frosst Canada Inc Process for preparing benzenealkanoic acid derivatives useful as leukotriene antagonists

Also Published As

Publication number Publication date
CN88101939A (zh) 1988-12-14
CA1327588C (en) 1994-03-08
IE881060L (en) 1988-10-10
SU1731042A3 (ru) 1992-04-30
AU1433488A (en) 1988-10-27
IE61277B1 (en) 1994-10-19
GR3005836T3 (es) 1993-06-07
DE3872576T2 (de) 1993-03-04
KR880012520A (ko) 1988-11-28
DE3872576D1 (de) 1992-08-13
PT87180A (pt) 1988-05-01
DK188388A (da) 1989-01-12
DK188388D0 (da) 1988-04-07
PH25349A (en) 1991-05-13
AU608311B2 (en) 1991-03-28
EP0288190A1 (en) 1988-10-26
JPS63277642A (ja) 1988-11-15
NZ224137A (en) 1991-01-29
EG18480A (en) 1993-04-30
US4874777A (en) 1989-10-17
PT87180B (pt) 1992-07-31
HUT54338A (en) 1991-02-28
HU203517B (en) 1991-08-28
ZA882420B (en) 1989-12-27
ATE78023T1 (de) 1992-07-15
EP0288190B1 (en) 1992-07-08

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ES2041791T3 (es) Mejoras en o relativas a antagonistas de leucotrienos.

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