ES2040339T3 - Procedimiento para preparar un granulo farmaceutico. - Google Patents
Procedimiento para preparar un granulo farmaceutico.Info
- Publication number
- ES2040339T3 ES2040339T3 ES198888304007T ES88304007T ES2040339T3 ES 2040339 T3 ES2040339 T3 ES 2040339T3 ES 198888304007 T ES198888304007 T ES 198888304007T ES 88304007 T ES88304007 T ES 88304007T ES 2040339 T3 ES2040339 T3 ES 2040339T3
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- procedure
- pharmaceutical granule
- cimetidine
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
L INVENCION PROPORCIONA UN PREPARADO FARMACEUTICO QUE CONTIENE CIMETIDINA DE 2-10% EN PESO EN RELACION A LA CIMETIDINA, DE UN COPOLIMERO DE METACRILATO DE DIMETILAMINOETILO Y ESTERES DE ACIDO METACRILICO NEUTROS. EL PREPARADO TIENE BUENAS CARACTERISTICAS DE PALATABILIDAD Y DE DISOLUCION.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878710965A GB8710965D0 (en) | 1987-05-08 | 1987-05-08 | Pharmaceutical compositions |
GB878710966A GB8710966D0 (en) | 1987-05-08 | 1987-05-08 | Pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2040339T3 true ES2040339T3 (es) | 1993-10-16 |
Family
ID=26292225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198888304007T Expired - Lifetime ES2040339T3 (es) | 1987-05-08 | 1988-05-04 | Procedimiento para preparar un granulo farmaceutico. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5188839A (es) |
EP (1) | EP0290229B1 (es) |
JP (1) | JP2721219B2 (es) |
KR (1) | KR960011236B1 (es) |
AU (1) | AU602582B2 (es) |
DE (1) | DE3863963D1 (es) |
ES (1) | ES2040339T3 (es) |
GB (1) | GB2204489B (es) |
GR (1) | GR3002410T3 (es) |
IE (1) | IE61692B1 (es) |
PT (1) | PT87423B (es) |
WO (1) | WO1988008703A1 (es) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5286489A (en) * | 1985-08-26 | 1994-02-15 | The Procter & Gamble Company | Taste masking compositions |
GB8710965D0 (en) * | 1987-05-08 | 1987-06-10 | Smith Kline French Lab | Pharmaceutical compositions |
US5230901A (en) * | 1988-03-23 | 1993-07-27 | Knoll Ag | Sustained release tablet of a mixture of alginates and polyacrylates |
DE3809764A1 (de) * | 1988-03-23 | 1989-10-05 | Knoll Ag | Mischung aus alginaten und polyacrylaten und deren verwendung |
DE68903605T2 (de) * | 1988-05-04 | 1993-04-01 | Smith Kline French Lab | Kautablette. |
US5219563A (en) * | 1988-05-11 | 1993-06-15 | Glaxo Group Limited | Drug adsorbates |
NZ230701A (en) * | 1988-09-20 | 1992-01-29 | Glaxo Group Ltd | Pharmaceutical compositions comprising ranitidine, alginic acid and a carbonate or bicarbonate |
ZA919510B (en) * | 1990-12-05 | 1992-10-28 | Smithkline Beecham Corp | Pharmaceutical compositions |
US5380535A (en) * | 1991-05-28 | 1995-01-10 | Geyer; Robert P. | Chewable drug-delivery compositions and methods for preparing the same |
ES2202302T3 (es) * | 1991-05-28 | 2004-04-01 | Mcneil-Ppc, Inc. | Composicion masticable que libera un farmaco. |
EG20380A (en) * | 1991-10-16 | 1999-02-28 | Richardson Vicks Inc | Enhanced skin penetration system for improved topical delivery of drugs |
GB9127150D0 (en) * | 1991-12-20 | 1992-02-19 | Smithkline Beecham Plc | Novel treatment |
US5294433A (en) * | 1992-04-15 | 1994-03-15 | The Procter & Gamble Company | Use of H-2 antagonists for treatment of gingivitis |
WO1993024109A1 (en) * | 1992-06-04 | 1993-12-09 | Smithkline Beecham Corporation | Palatable pharmaceutical compositions |
GB9224855D0 (en) * | 1992-11-27 | 1993-01-13 | Smithkline Beecham Plc | Pharmaceutical compositions |
CA2110313C (en) * | 1992-12-01 | 2004-10-26 | Edward John Roche | Pharmaceutical compositions containing a guanidinothiazole compound and antacids |
US5622980A (en) * | 1993-08-17 | 1997-04-22 | Applied Analytical Industries, Inc. | Oral compositions of H2-antagonists |
US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
US6080428A (en) | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
US6676967B1 (en) * | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
US20060263428A1 (en) * | 1993-09-20 | 2006-11-23 | Eugenio Cefali | Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics |
SE9600071D0 (sv) † | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients I |
US6183775B1 (en) * | 1996-05-13 | 2001-02-06 | Novartis Consumer Health S.A. | Buccal delivery system |
CA2258159C (en) * | 1996-06-14 | 2006-03-21 | Kyowa Hakko Kogyo Co., Ltd. | Intraorally rapidly disintegrable tablet |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
JP2001501224A (ja) * | 1996-10-04 | 2001-01-30 | メルク エンド カンパニー インコーポレーテッド | 胸焼けを予防及び治療するための方法及び組成物 |
US5989588A (en) * | 1996-10-04 | 1999-11-23 | Merck & Co., Inc. | Methods and compositions for preventing and treating heartburn |
FR2766089B1 (fr) * | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
IN186245B (es) * | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
WO2000028988A1 (en) * | 1998-11-17 | 2000-05-25 | Nitromed, Inc. | Nitrosated and nitrosylated h2 receptor antagonist compounds, compositions and methods of use |
FR2794979B1 (fr) * | 1999-06-21 | 2001-07-27 | Patrick Veret | Une nouvelle formulation de comprime composee de lactose, sorbitol, stearate de magnesium |
PT1276470E (pt) | 2000-04-20 | 2007-08-13 | Novartis Ag | Composição de revestimento para dissimular o sabor |
US6551617B1 (en) | 2000-04-20 | 2003-04-22 | Bristol-Myers Squibb Company | Taste masking coating composition |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
US20030170310A1 (en) * | 2002-03-08 | 2003-09-11 | Hardeep Wadhwa | Tasteless, directly compressible, fast-dissolving complexes and pharmaceutical formulations thereof |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
ITMI20041255A1 (it) * | 2004-06-22 | 2004-09-22 | Univ Degli Studi Milano | Sistemi microparticellari per somministrazione orale di sostanze biologicamente attive |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US20060127479A1 (en) * | 2004-10-08 | 2006-06-15 | Natrajan Kumaraperumal | Solvent free taste masked pharmaceutical compositions |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
NZ589750A (en) | 2004-10-21 | 2012-07-27 | Aptalis Pharmatech Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
US7776831B2 (en) | 2006-02-01 | 2010-08-17 | Weg Stuart L | Use of antifungal compositions to treat upper gastrointestinal conditions |
AU2010325746B2 (en) | 2009-12-02 | 2016-02-25 | Adare Pharmaceuticals S.R.L. | Fexofenadine microcapsules and compositions containing them |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5840529B2 (ja) * | 1975-09-29 | 1983-09-06 | 明治製菓株式会社 | ケイコウヨウセイザイノセイホウ |
JPS5513239A (en) * | 1978-07-14 | 1980-01-30 | Fujisawa Pharmaceut Co Ltd | Fine particulate drug composition |
JPS5567375A (en) * | 1978-11-17 | 1980-05-21 | Harunobu Miura | Automatic washer |
JPS56164122A (en) * | 1980-05-21 | 1981-12-17 | Fujimoto Seiyaku Kk | Drug composition comprising cimetidine as main agent |
JPS58201725A (ja) * | 1982-05-19 | 1983-11-24 | Eisai Co Ltd | 褐変化防止組成物 |
EP0205336B1 (en) * | 1985-06-11 | 1991-09-11 | Teijin Limited | Oral sustained release pharmaceutical preparation |
FR2593065B1 (fr) * | 1986-01-22 | 1988-09-09 | Smith Kline French Lab | Couples effervescents, compositions effervescentes d'antagonistes h2 de l'histamine les contenant et leur preparation. |
US4800087A (en) * | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
JPS63188621A (ja) * | 1987-01-30 | 1988-08-04 | Taisho Pharmaceut Co Ltd | 矯味経口製剤 |
GB8710965D0 (en) * | 1987-05-08 | 1987-06-10 | Smith Kline French Lab | Pharmaceutical compositions |
-
1987
- 1987-05-04 KR KR1019890700007A patent/KR960011236B1/ko not_active IP Right Cessation
-
1988
- 1988-05-04 ES ES198888304007T patent/ES2040339T3/es not_active Expired - Lifetime
- 1988-05-04 WO PCT/GB1988/000349 patent/WO1988008703A1/en unknown
- 1988-05-04 EP EP88304007A patent/EP0290229B1/en not_active Expired - Lifetime
- 1988-05-04 JP JP63503930A patent/JP2721219B2/ja not_active Expired - Lifetime
- 1988-05-04 DE DE8888304007T patent/DE3863963D1/de not_active Expired - Lifetime
- 1988-05-04 US US07/295,190 patent/US5188839A/en not_active Expired - Lifetime
- 1988-05-04 GB GB8810477A patent/GB2204489B/en not_active Revoked
- 1988-05-04 AU AU17140/88A patent/AU602582B2/en not_active Expired
- 1988-05-05 PT PT87423A patent/PT87423B/pt not_active IP Right Cessation
- 1988-05-06 IE IE136888A patent/IE61692B1/en not_active IP Right Cessation
-
1991
- 1991-08-01 GR GR91401072T patent/GR3002410T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE3863963D1 (de) | 1991-09-05 |
EP0290229A1 (en) | 1988-11-09 |
IE61692B1 (en) | 1994-11-16 |
JP2721219B2 (ja) | 1998-03-04 |
PT87423A (pt) | 1989-05-31 |
GB2204489A (en) | 1988-11-16 |
GB2204489B (en) | 1990-11-14 |
GR3002410T3 (en) | 1992-12-30 |
KR960011236B1 (ko) | 1996-08-21 |
IE881368L (en) | 1988-11-08 |
US5188839A (en) | 1993-02-23 |
WO1988008703A1 (en) | 1988-11-17 |
EP0290229B1 (en) | 1991-07-31 |
KR890701101A (ko) | 1989-12-19 |
AU602582B2 (en) | 1990-10-18 |
JPH01503385A (ja) | 1989-11-16 |
GB8810477D0 (en) | 1988-06-08 |
PT87423B (pt) | 1992-09-30 |
AU1714088A (en) | 1988-12-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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