ES2038093T1 - Uso del enantiomero s(+) ibuprofeno. - Google Patents
Uso del enantiomero s(+) ibuprofeno.Info
- Publication number
- ES2038093T1 ES2038093T1 ES199090905892T ES90905892T ES2038093T1 ES 2038093 T1 ES2038093 T1 ES 2038093T1 ES 199090905892 T ES199090905892 T ES 199090905892T ES 90905892 T ES90905892 T ES 90905892T ES 2038093 T1 ES2038093 T1 ES 2038093T1
- Authority
- ES
- Spain
- Prior art keywords
- ibuprofen
- mammalian
- principle
- enantiomer
- ibuprofen enantiomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE OBTIENE UNA RESPUESTA ANTIPIRETICA ACELERADA E INTENSIFICADA AL PRINCIPIO EN UN ORGANISMO DE UN MAMIFERO QUE NECESITA TAL TRATAMIENTO, ES DECIR, UN MAMIFERO QUE TIENE UNA TEMPERATURA CORPORAL ELEVADA (FIEBRE), MEDIANTE LA ADMINISTRACION AL MISMO DE UNA CANTIDAD EFICAZ ANTIPIRETICAMENTE ACELERADORA/INTENSIFICADORA AL PRINCIPIO DE UNA DOSIS UNITARIA DEL ENASTIOMERO DE IBUPROFENO S(T), ESTANDO DICHO ENANTIOMERO SUSTANCIALMENTE LIBRE DE SU ANTIPODO DE IBUPROFENO R(-).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/356,850 US4980375A (en) | 1987-07-10 | 1989-05-25 | Onset-hastened/enhanced antipyretic response |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2038093T1 true ES2038093T1 (es) | 1993-07-16 |
Family
ID=23403222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES199090905892T Pending ES2038093T1 (es) | 1989-05-25 | 1990-04-04 | Uso del enantiomero s(+) ibuprofeno. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4980375A (es) |
| EP (1) | EP0473604A4 (es) |
| JP (1) | JPH04505758A (es) |
| KR (1) | KR920700630A (es) |
| AU (1) | AU630687B2 (es) |
| CA (1) | CA2057034C (es) |
| ES (1) | ES2038093T1 (es) |
| NZ (1) | NZ233750A (es) |
| WO (1) | WO1990014081A1 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8764191A (en) * | 1990-09-28 | 1992-04-28 | Mcneill-Ppc Inc. | Ibuprofen-antihistamine combinations |
| EP0577757A1 (en) * | 1991-04-01 | 1994-01-12 | Merck & Co. Inc. | Ibuprofen-decongestant combinations |
| US5164398A (en) * | 1991-04-01 | 1992-11-17 | Merck & Co., Inc. | Ibuprofen-antitussive combinations |
| ES2148175T3 (es) * | 1991-05-13 | 2000-10-16 | Boots Co Plc | Composicion farmaceutica que contiene una sal de ibuprofeno. |
| DE4140183C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Retardform für ein Flurbiprofen enthaltendes Arzneimittel |
| DE4140179C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Akutform für ein Ibuprofen enthaltendes Arzneimittel |
| DE4140185C2 (de) * | 1991-12-05 | 1996-02-01 | Alfatec Pharma Gmbh | Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung |
| DE4140184C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Akutform für ein Flurbiprofen enthaltendes Arzneimittel |
| DE4140172C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Retardform für ein Ibuprofen enthaltendes Arzneimittel |
| US5288507A (en) * | 1992-07-29 | 1994-02-22 | Merck & Co., Inc. | Ibuprofen antacid combinations |
| US5260337A (en) * | 1992-07-29 | 1993-11-09 | Merck & Co., Inc. | Ibuprofen-muscle relaxant combinations |
| US5718919A (en) * | 1995-02-24 | 1998-02-17 | Nanosystems L.L.C. | Nanoparticles containing the R(-)enantiomer of ibuprofen |
| US6348216B1 (en) * | 1996-06-10 | 2002-02-19 | Knoll Pharmaceutical Company | Ibuprofen and narcotic analgesic compositions |
| US6361794B1 (en) | 1996-06-12 | 2002-03-26 | Basf Corporation | Method of making ibuprofen and narcotic analgesic composition |
| US6211246B1 (en) | 1999-06-10 | 2001-04-03 | Mcneil-Ppc, Inc. | Rapidly absorbed liquid compositions |
| DE10003757A1 (de) * | 2000-01-28 | 2001-08-02 | Knoll Ag | Ibuprofen-Wirkstoffzubereitung |
| US20040132823A1 (en) * | 2001-11-02 | 2004-07-08 | Leo Pavliv | Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid |
| EP2149546A1 (en) * | 2008-07-31 | 2010-02-03 | Laboratorios Del. Dr. Esteve, S.A. | Salts of tramadol and ibuprofen and their crystal form in the treatment of pain |
| EP2445486B1 (en) * | 2009-06-22 | 2017-11-08 | Wyeth LLC | Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4701470A (en) * | 1982-12-06 | 1987-10-20 | The Upjohn Company | Treatment of Type II Herpes virus with ibuprofen |
| JPS59222409A (ja) * | 1983-06-01 | 1984-12-14 | Nippon Redarii Kk | 消炎鎮痛ゲル軟膏剤 |
| JPS60209515A (ja) * | 1984-04-03 | 1985-10-22 | Hokuriku Seiyaku Co Ltd | 消炎鎮痛クリ−ム剤 |
| DE3437599A1 (de) * | 1984-10-13 | 1986-04-17 | Dolorgiet GmbH & Co KG, 5205 St Augustin | Ibuprofen enthaltende weichgelatinekapseln und verfahren zu ihrer herstellung |
| DE3440288A1 (de) * | 1984-11-05 | 1986-05-07 | Gergely, Gerhard, Dr.-Ing., Wien | Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung |
| ATE50493T1 (de) * | 1986-11-14 | 1990-03-15 | Puetter Medice Chem Pharm | Ibuprofen enthaltendes arzneimittel. |
| US4851444A (en) * | 1987-07-10 | 1989-07-25 | Analgesic Associates | Onset-hastened/enhanced analgesia |
| GB8716975D0 (en) * | 1987-07-17 | 1987-08-26 | Boots Co Plc | Therapeutic agents |
-
1989
- 1989-05-25 US US07/356,850 patent/US4980375A/en not_active Expired - Fee Related
-
1990
- 1990-04-04 EP EP19900905892 patent/EP0473604A4/en not_active Ceased
- 1990-04-04 ES ES199090905892T patent/ES2038093T1/es active Pending
- 1990-04-04 KR KR1019910701662A patent/KR920700630A/ko not_active Application Discontinuation
- 1990-04-04 WO PCT/US1990/001710 patent/WO1990014081A1/en not_active Application Discontinuation
- 1990-04-04 AU AU53588/90A patent/AU630687B2/en not_active Withdrawn - After Issue
- 1990-04-04 CA CA002057034A patent/CA2057034C/en not_active Expired - Fee Related
- 1990-04-04 JP JP2505573A patent/JPH04505758A/ja active Pending
- 1990-05-21 NZ NZ233750A patent/NZ233750A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU630687B2 (en) | 1992-11-05 |
| CA2057034A1 (en) | 1990-11-26 |
| EP0473604A1 (en) | 1992-03-11 |
| US4980375A (en) | 1990-12-25 |
| NZ233750A (en) | 1997-06-24 |
| EP0473604A4 (en) | 1992-04-15 |
| JPH04505758A (ja) | 1992-10-08 |
| WO1990014081A1 (en) | 1990-11-29 |
| AU5358890A (en) | 1990-12-18 |
| KR920700630A (ko) | 1992-08-10 |
| CA2057034C (en) | 1999-04-13 |
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