ES2037862T3 - Aplicacion de grupos nitrofenilos a la estimulacion de las capacidades de incorporacion de un medicamento en las celulas sensibles del huesped. - Google Patents

Aplicacion de grupos nitrofenilos a la estimulacion de las capacidades de incorporacion de un medicamento en las celulas sensibles del huesped.

Info

Publication number
ES2037862T3
ES2037862T3 ES198888402734T ES88402734T ES2037862T3 ES 2037862 T3 ES2037862 T3 ES 2037862T3 ES 198888402734 T ES198888402734 T ES 198888402734T ES 88402734 T ES88402734 T ES 88402734T ES 2037862 T3 ES2037862 T3 ES 2037862T3
Authority
ES
Spain
Prior art keywords
application
guest
stimulation
medicinal product
sensitive cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888402734T
Other languages
English (en)
Inventor
Eustrate-Stratis Avrameas
Panayota Matsiota-Bernard
Therese Ternynck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Application granted granted Critical
Publication of ES2037862T3 publication Critical patent/ES2037862T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA INVENCION SE REFIERE A LA APLICACION DE AGRUPAMIENTOS NITROFENILOS, A LA MODIFICACION DE PRINCIPIOS ACTIVOS DE MEDICAMENTOS A FIN DE FAVORECER SU INCORPORACION A LAS CELULAS SENSIBLES DEL HUESPED AL QUE EL MEDICAMENTO ESTA DESTINADO. LA INVENCION SE REFIERE A CONJUGADOS QUE RESULTAN DE UN ACOPLAMIENTO ENTRE UN PRINCIPIO ACTIVO DE MEDICAMENTO Y UN NITROFENILO. LA INVENCION SE REFIERE ADEMAS A LA APLICACION DE ESTOS CONJUGADOS A LA FABRICACION DE COMPOSICION FARMACEUTICA.
ES198888402734T 1987-10-30 1988-10-28 Aplicacion de grupos nitrofenilos a la estimulacion de las capacidades de incorporacion de un medicamento en las celulas sensibles del huesped. Expired - Lifetime ES2037862T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8715127A FR2622445B1 (fr) 1987-10-30 1987-10-30 Application de groupes nitrophenyles a la stimulation des capacites d'incorporation d'un medicament dans les cellules sensibles de l'hote

Publications (1)

Publication Number Publication Date
ES2037862T3 true ES2037862T3 (es) 1993-07-01

Family

ID=9356379

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888402734T Expired - Lifetime ES2037862T3 (es) 1987-10-30 1988-10-28 Aplicacion de grupos nitrofenilos a la estimulacion de las capacidades de incorporacion de un medicamento en las celulas sensibles del huesped.

Country Status (9)

Country Link
EP (1) EP0314580B1 (es)
JP (1) JPH02501933A (es)
AT (1) ATE66602T1 (es)
DE (1) DE3864490D1 (es)
DK (1) DK328189D0 (es)
ES (1) ES2037862T3 (es)
FR (1) FR2622445B1 (es)
GR (1) GR3002665T3 (es)
WO (1) WO1989003680A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MC2246A1 (fr) * 1990-04-03 1993-03-25 Radopath Ltd Utilisation de trinitrobenzenes ou d'acide carminique dans le traitement du cancer ou des maladies virales

Also Published As

Publication number Publication date
FR2622445B1 (fr) 1990-07-27
GR3002665T3 (en) 1993-01-25
EP0314580A1 (fr) 1989-05-03
JPH02501933A (ja) 1990-06-28
FR2622445A1 (fr) 1989-05-05
DK328189A (da) 1989-06-30
ATE66602T1 (de) 1991-09-15
WO1989003680A1 (fr) 1989-05-05
DK328189D0 (da) 1989-06-30
EP0314580B1 (fr) 1991-08-28
DE3864490D1 (de) 1991-10-02

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