ES2033850T5 - Forma farmaceutica consistente en una combinacion dosificada, destinada al tratamiento de las mujeres pre-menopausicas. - Google Patents

Forma farmaceutica consistente en una combinacion dosificada, destinada al tratamiento de las mujeres pre-menopausicas.

Info

Publication number
ES2033850T5
ES2033850T5 ES87306174T ES87306174T ES2033850T5 ES 2033850 T5 ES2033850 T5 ES 2033850T5 ES 87306174 T ES87306174 T ES 87306174T ES 87306174 T ES87306174 T ES 87306174T ES 2033850 T5 ES2033850 T5 ES 2033850T5
Authority
ES
Spain
Prior art keywords
days
dosage form
combination
treatment
intended
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87306174T
Other languages
English (en)
Other versions
ES2033850T3 (es
Inventor
Gertrude Virginia Upton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25388101&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2033850(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of ES2033850T3 publication Critical patent/ES2033850T3/es
Publication of ES2033850T5 publication Critical patent/ES2033850T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

SE DESCRIBE AQUI UN METODO PARA APLICAR UNA TERAPIA DE SUSTITUCION HORMONAL Y UN ANTICONCEPTIVO A UNA MUJER PREMENOPAUSICA, QUE COMPRENDE ADMINSTRAR A UNA MUJER PREMENOPAUSICA QUE LA NECESITA UNA FORMA DE DOSIFICACION COMBINADA DE UN ESTROGENO SELECCIONADO DE ENTRE 0,5-2,0 MG DE 17 BETA-ESTRADIOL, 0,008-0,030 MG DE ETINIL ESTRADIOL Y 0,015-0,060 MG DE MESTRANOL; Y UN PROGETOGENO SELECIONADO DE ENTRE 0,025-0,100 MG DE LEVONORGESTREL, 0,010-0, 070 MG DE GESTODENE, 0,025-0,100 MG DE DESOGESTREL 0,025-0,100 MG DE 3-CETODESOGESTREL Y 0,085-0,35 MG DE NORETINDRONA, ADMINISTRANDOSE DICHA FORMA DE DOSIFICACION COMBINADA DURANTE 23-25 DIAS Y EMPEZANDO EN EL PRIMER DIA DEL CICLO MENSTRUAL, SEGUIDA POR 2 A 5 DIAS SIN PILDORAS O CON PILDORAS PLACEBO DURANTE UN TOTAL DE 28 DIAS DEL CICLO DE ADMINSTRACION. LA FORMA DE DOSIFICACION PREFERIDA DE LA INVENCION ES UNA COMBINACION DE 1 MG DE 17BETA-ESTRADIOL Y 0,050 O 0,075 MG DE LEVONORGESTREL. EL CICLO DE ADMINISTRACION PREFERIDO DE LA INVENCION ES LA ADMINISTRACION DE LA FORMA DE DOSIFICACION COMBINADA DURANTE LOS PRIMEROS 24 DIAS DEL CICLO MENSTRUAL Y NINGUNA FORMA DE DOSIFICACION DURANTE LOS ULTIMOS 4 DIAS DEL CICLO MENSTRUAL.
ES87306174T 1986-07-15 1987-07-13 Forma farmaceutica consistente en una combinacion dosificada, destinada al tratamiento de las mujeres pre-menopausicas. Expired - Lifetime ES2033850T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88597186A 1986-07-15 1986-07-15

Publications (2)

Publication Number Publication Date
ES2033850T3 ES2033850T3 (es) 1993-04-01
ES2033850T5 true ES2033850T5 (es) 2001-07-01

Family

ID=25388101

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87306174T Expired - Lifetime ES2033850T5 (es) 1986-07-15 1987-07-13 Forma farmaceutica consistente en una combinacion dosificada, destinada al tratamiento de las mujeres pre-menopausicas.

Country Status (20)

Country Link
EP (1) EP0253607B2 (es)
JP (1) JP2645510B2 (es)
KR (1) KR960001371B1 (es)
AT (1) ATE75401T1 (es)
AU (1) AU597084B2 (es)
CY (1) CY1725A (es)
DE (1) DE3778599D1 (es)
DK (2) DK174724B1 (es)
ES (1) ES2033850T5 (es)
GB (1) GB2192542B (es)
GR (1) GR3004472T3 (es)
HK (1) HK67393A (es)
IE (1) IE61236B1 (es)
LU (1) LU90634I2 (es)
NL (1) NL300025I2 (es)
PH (1) PH25944A (es)
PT (1) PT85305B (es)
SG (1) SG55093G (es)
WO (1) WO1988000469A1 (es)
ZA (1) ZA875010B (es)

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DE3864210D1 (de) * 1987-07-06 1991-09-19 Akzo Nv Pharmazeutische dosierungseinheit zur vorbeugung bzw. behandlung von klimakterischen beschwerden.
ES2169030T3 (es) * 1987-09-24 2002-07-01 Jencap Res Ltd Envases de anticonceptivos que contienen estrogeno y progestina.
US5276022A (en) * 1987-09-24 1994-01-04 Jencap Research Ltd. Hormone preparation and method
DE3916112A1 (de) * 1989-05-16 1990-11-22 Schering Ag Dihydrospirorenon als antiandrogen
US5043331A (en) * 1989-06-15 1991-08-27 Orion-Yhtyma Oy Treatment of postmenopausal disorders
IE71203B1 (en) * 1990-12-13 1997-02-12 Akzo Nv Low estrogen oral contraceptives
IE62665B1 (en) * 1990-12-17 1995-02-22 Akzo Nv Contraceptive regimen
MX9301121A (es) * 1992-03-02 1993-09-01 Schering Ag Metodo y equipo para la contracepcion oral y regulacion de la menstruacion con estrogeno/progestina/aniprogestina.
US7704983B1 (en) 1992-03-02 2010-04-27 Eastern Virginia Medical School Antiprogestin method for reducing side effects associated with low dosage HRT and oral contraception
DE4227989A1 (de) * 1992-08-21 1994-06-09 Schering Ag Mittel zur transdermalen Applikation enthaltend 3-Keto-desogestrel
DE4344462C2 (de) * 1993-12-22 1996-02-01 Schering Ag Zusammensetzung für die Empfängnisverhütung
US5552394A (en) * 1994-07-22 1996-09-03 The Medical College Of Hampton Roads Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy
US5922349A (en) * 1995-09-28 1999-07-13 Schering Aktiengesellschaft Hormone replacement therapy method and hormone dispenser
US5747480A (en) * 1996-05-08 1998-05-05 American Home Products Corporation Oral contraceptive
US6451778B1 (en) 1996-07-26 2002-09-17 Wyeth Oral contraceptive
US6479475B1 (en) 1996-07-26 2002-11-12 Wyeth Oral contraceptive
ATE271386T1 (de) * 1996-07-26 2004-08-15 Wyeth Corp Orale einstufige empfängnisverhütungsmethode und kombinationspräparat das gestagen und estrogen enthält
US5888543A (en) * 1996-07-26 1999-03-30 American Home Products Corporation Oral contraceptives
US5858405A (en) * 1996-07-26 1999-01-12 American Home Products Corporation Oral contraceptive
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US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
WO2001030355A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
US5898032A (en) * 1997-06-23 1999-04-27 Medical College Of Hampton Roads Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy
JP2001513566A (ja) * 1997-08-27 2001-09-04 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 経口避妊における、エストロゲンと子宮内膜節約性プロゲスチンおよび子宮内膜萎縮性プロゲスチンとの組み合わせ物
US6787531B1 (en) 1999-08-31 2004-09-07 Schering Ag Pharmaceutical composition for use as a contraceptive
US20020132801A1 (en) * 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
FR2832065B1 (fr) 2001-11-13 2004-11-05 Besins Int Belgique Composition pharmaceutique a base de progesterone micronisee son procede de preparation et ses utilisations
WO2003049744A1 (en) 2001-12-05 2003-06-19 Barr Laboratories, Inc. Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology
US7772219B2 (en) 2003-05-02 2010-08-10 Teva Women's Health, Inc. Methods of hormonal treatment utilizing extended cycle contraceptive regimens
CN101001631B (zh) 2003-07-16 2014-08-06 特卫华妇女健康有限公司 利用连续给予雌激素的避孕方案的激素治疗方法
WO2005049142A2 (en) * 2003-11-14 2005-06-02 Warner Chilcott Company, Inc. Graduated estrogen contraceptive
EP1535618A1 (en) 2003-11-26 2005-06-01 Schering Aktiengesellschaft Pharmaceutical preparation for continuous hormonal treatment over a period of longer than 21-28 days comprising two estrogen and/or progestin compositions
DE102004019743B4 (de) 2004-04-20 2008-11-27 Bayer Schering Pharma Aktiengesellschaft Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens
DE102004026679A1 (de) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
DE102004026670A1 (de) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
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WO2009082478A1 (en) 2007-12-20 2009-07-02 Duramed Pharmaceuticals, Inc. Dosage regimens and pharmaceutical compositions and packages for emergency contraception
WO2009112232A2 (en) * 2008-03-10 2009-09-17 Vladimir Hanes New drospirenone/17beta-estradiol regimen, pharmaceutical combination product and kit for performing this regimen
EP2343963B1 (en) 2008-10-08 2019-04-10 Agile Therapeutics, Inc. Transdermal delivery
ES2795455T3 (es) 2008-10-08 2020-11-23 Agile Therapeutics Inc Suministro transdérmico
US9192614B2 (en) 2008-10-08 2015-11-24 Agile Therapeutics, Inc. Contraceptive transdermal delivery of hormones
WO2010111488A1 (en) 2009-03-27 2010-09-30 Agile Therapeutics, Inc. Transdermal delivery
US20180125860A1 (en) * 2015-05-18 2018-05-10 Agile Therapeutics, Inc. Contraceptive Compositions and Methods for Improved Efficacy and Modulation of Side Effects
EP3272333A1 (en) 2016-07-22 2018-01-24 Chemo Research, S.L. Vaginal composition comprising a combination of estrogen and vitamin d

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Also Published As

Publication number Publication date
KR880701553A (ko) 1988-11-03
ZA875010B (en) 1989-02-22
DK351887A (da) 1988-01-16
GR3004472T3 (es) 1993-03-31
JPH01500431A (ja) 1989-02-16
EP0253607B2 (en) 2001-05-23
WO1988000469A1 (en) 1988-01-28
PT85305B (pt) 1990-03-30
ATE75401T1 (de) 1992-05-15
GB8716431D0 (en) 1987-08-19
LU90634I2 (fr) 2000-12-15
GB2192542A (en) 1988-01-20
AU597084B2 (en) 1990-05-24
AU7537987A (en) 1988-01-21
PH25944A (en) 1991-12-19
KR960001371B1 (ko) 1996-01-26
PT85305A (en) 1987-08-01
DK174724B1 (da) 2003-10-06
NL300025I1 (nl) 2001-01-02
CY1725A (en) 1994-05-06
HK67393A (en) 1993-07-23
IE871833L (en) 1988-01-15
JP2645510B2 (ja) 1997-08-25
DK351887D0 (da) 1987-07-08
DE3778599D1 (de) 1992-06-04
GB2192542B (en) 1990-05-02
NL300025I2 (nl) 2004-08-02
SG55093G (en) 1993-07-09
IE61236B1 (en) 1994-10-19
EP0253607A1 (en) 1988-01-20
ES2033850T3 (es) 1993-04-01
EP0253607B1 (en) 1992-04-29
DK365887D0 (da) 1987-07-14

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