ES2032280T3 - Saponinas de triterpeno que poseen actividad antiinflamatoria, mucolitica y antiedemica, proceso para su preparacion y composiciones farmaceuticas que las contienen. - Google Patents

Saponinas de triterpeno que poseen actividad antiinflamatoria, mucolitica y antiedemica, proceso para su preparacion y composiciones farmaceuticas que las contienen.

Info

Publication number
ES2032280T3
ES2032280T3 ES198787109117T ES87109117T ES2032280T3 ES 2032280 T3 ES2032280 T3 ES 2032280T3 ES 198787109117 T ES198787109117 T ES 198787109117T ES 87109117 T ES87109117 T ES 87109117T ES 2032280 T3 ES2032280 T3 ES 2032280T3
Authority
ES
Spain
Prior art keywords
saponins
triterpen
inflammatory
mucolitic
demic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787109117T
Other languages
English (en)
Inventor
Piero Foresta
Orlando Ghirardi
Bruno Gabetta
Aldo Cristoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IDB Holding SpA
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
IDB Holding SpA
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IDB Holding SpA, Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical IDB Holding SpA
Application granted granted Critical
Publication of ES2032280T3 publication Critical patent/ES2032280T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LAS SAPONINAS DE TRITERPENOS DE FORMULA (I) DONDE R1 ES H U OH Y R2 ES UNA CADENA TETRASACARIDA O ALTERNATIVAMENTE PENTASACARIDA, TIENEN ACTIVIDADES ANTIINFLAMATORIAS, MUCOLITICAS Y ANTIEDEMATOSAS. DICHAS SAPONINAS SE AISLAN DE RAICES Y CORTEZA DE CROSSOPTERIX FEBRIFUGA, POR EJEMPLO, PRECIPITANDOLAS, EN FORMA DE COMPLEJO CON COLESTEROL O SITOSTEROL, DE UN EXTRACTO ALCOHOLICO DEL MATERIAL VEGETAL Y SEPARANDO EL PRECIPITADO POR REPARTO ENTRE UN DISOLVENTE APOLAR QUE SUSTRAE EL AGENTE COMPLEJANTE Y UN DISOLVENTE POLAR EN EL QUE SON SOLUBLES LAS SAPONINAS.
ES198787109117T 1986-07-01 1987-06-25 Saponinas de triterpeno que poseen actividad antiinflamatoria, mucolitica y antiedemica, proceso para su preparacion y composiciones farmaceuticas que las contienen. Expired - Lifetime ES2032280T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48208/86A IT1195849B (it) 1986-07-01 1986-07-01 Saponine triterpeniche ad attivita' antiinfiammatoria,mucolitica ed antiedemigena,procedimento per il loro ottenimento e composizioni farmaceutiche che li comprendono

Publications (1)

Publication Number Publication Date
ES2032280T3 true ES2032280T3 (es) 1993-02-01

Family

ID=11265244

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787109117T Expired - Lifetime ES2032280T3 (es) 1986-07-01 1987-06-25 Saponinas de triterpeno que poseen actividad antiinflamatoria, mucolitica y antiedemica, proceso para su preparacion y composiciones farmaceuticas que las contienen.

Country Status (7)

Country Link
US (1) US4879376A (es)
EP (1) EP0251197B1 (es)
AT (1) ATE71950T1 (es)
DE (1) DE3776208D1 (es)
ES (1) ES2032280T3 (es)
GR (1) GR3004222T3 (es)
IT (1) IT1195849B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079232A (en) * 1988-12-09 1992-01-07 Kyowa Hakko Rogyo Kabushiki Kaisha Compound ks-505 useful for improving cerebral function
US5723149A (en) * 1990-11-21 1998-03-03 Lvmh Recherche Use of medicago saponins for the preparation of cosmetic or pharmaceutical compositions, especially dermatological compositions, promoting renewal of the epidermis, stimulating hair regrowth or delaying hair loss
US5356880A (en) * 1991-05-30 1994-10-18 Sanwa Kagaku Kenkyusho Co., Ltd. Glycyrrhetinic acid derivatives
US6162459A (en) * 1995-02-24 2000-12-19 National Science Council Acyclovir transdermal delivery system
US5797891A (en) * 1996-10-29 1998-08-25 Nouveau Technologies, Inc. Sanitary control device
JP4790620B2 (ja) * 2003-11-27 2011-10-12 グリフィス ユニバーシティ 新規な鎮痛性化合物，これを含有する抽出物及びその製造方法
GB0513881D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors III
GB0329667D0 (en) * 2003-12-22 2004-01-28 King S College London Core 2 GlcNAc-T inhibitor
US20080182801A1 (en) 2003-12-22 2008-07-31 Btg International Limited Core 2 glcnac-t inhibitors
GB0513888D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
EP2116253A1 (en) * 2008-05-07 2009-11-11 Phytrix JV, LLC Novel phyllanthus extract
WO2012033634A2 (en) 2010-09-09 2012-03-15 Mary Kay Inc. Topical skin care formulations comprising plant extracts

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT246338B (de) * 1963-01-17 1966-04-12 Heilmittelwerke Wien Ges Mit B Verfahren zur Herstellung von neuen Derivaten der Primulasäure
JPS5423965B2 (es) * 1972-04-24 1979-08-17
US3886272A (en) * 1973-07-30 1975-05-27 Stanford Research Inst Saponin-containing spermatocidal compositions
US4103025A (en) * 1974-01-29 1978-07-25 Inverni Della Beffa S.P.A. Novel terpenes
DE2543053A1 (de) * 1975-09-26 1977-03-31 Vsesojusny Nii Lekarstvennych Arzneimittel von tranquillisierender, hypotensiver, kardiotonischer und antisklerotischer wirkung
JPS54132218A (en) * 1978-04-01 1979-10-15 Toyo Soda Mfg Co Ltd Separation of saponin constituents
FR2460136B1 (fr) * 1979-07-05 1986-01-10 Synthelabo Compositions pharmaceutiques contenant des extraits de lierre grimpant
DE3040246C2 (de) * 1979-10-29 1985-01-10 Osaka Chemical Laboratory Co., Ltd., Osaka Sojasaponine A↓1↓ und A↓2↓ und ihre Verwendung

Also Published As

Publication number Publication date
ATE71950T1 (de) 1992-02-15
DE3776208D1 (de) 1992-03-05
IT8648208A0 (it) 1986-07-01
EP0251197A3 (en) 1988-09-14
US4879376A (en) 1989-11-07
GR3004222T3 (es) 1993-03-31
EP0251197B1 (en) 1992-01-22
IT1195849B (it) 1988-10-27
EP0251197A2 (en) 1988-01-07

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