ES2032278T3 - Particulas de dioxido de cromo recubiertas. - Google Patents

Particulas de dioxido de cromo recubiertas.

Info

Publication number
ES2032278T3
ES2032278T3 ES198787103692T ES87103692T ES2032278T3 ES 2032278 T3 ES2032278 T3 ES 2032278T3 ES 198787103692 T ES198787103692 T ES 198787103692T ES 87103692 T ES87103692 T ES 87103692T ES 2032278 T3 ES2032278 T3 ES 2032278T3
Authority
ES
Spain
Prior art keywords
dioxide particles
chrome coated
core
immunoassays
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787103692T
Other languages
English (en)
Inventor
Hon-Peng Phillip Lau
Esther Koo Yang
Howard Wayne Jacobson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of ES2032278T3 publication Critical patent/ES2032278T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/86—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2995—Silane, siloxane or silicone coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hard Magnetic Materials (AREA)
  • Silicon Compounds (AREA)
  • Glanulating (AREA)
  • Chemically Coating (AREA)
  • Peptides Or Proteins (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Compounds Of Iron (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

EL DIOXIDO DE CROMO TIENE PROPIEDADES MAGNETICAS FAVORABLES, QUE LE HACEN CODICIABLE COMO SOPORTE SOLIDO EN INMUNOENSAYOS HETEROGENEOS. NO OBSTANTE, PARA SER UTIL EN TALES ENSAYOS HA DE ESTAR PROTEGIDO CONTRA LA DEGRADACION HIDROLITICA. ESTA INVENCION PROPORCIONA PARTICULAS MAGNETICAS UTILES EN INMUNOENSAYOS QUE TIENEN UN NUCLEO DE CRO2, QUE TIENE UNA SUPERFICIE REDUCIDA, REVESTIDO CON SILICE Y CON UN SILANO.
ES198787103692T 1986-03-18 1987-03-14 Particulas de dioxido de cromo recubiertas. Expired - Lifetime ES2032278T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/841,107 US4661408A (en) 1986-03-18 1986-03-18 Coated chromium dioxide particles

Publications (1)

Publication Number Publication Date
ES2032278T3 true ES2032278T3 (es) 1993-02-01

Family

ID=25284035

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787103692T Expired - Lifetime ES2032278T3 (es) 1986-03-18 1987-03-14 Particulas de dioxido de cromo recubiertas.

Country Status (10)

Country Link
US (1) US4661408A (es)
EP (1) EP0240770B1 (es)
JP (1) JPS62226817A (es)
AT (1) ATE72050T1 (es)
CA (1) CA1289873C (es)
DE (1) DE3776180D1 (es)
DK (1) DK136787A (es)
ES (1) ES2032278T3 (es)
GR (1) GR3003647T3 (es)
IE (1) IE60178B1 (es)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
JPH02503983A (ja) * 1987-06-26 1990-11-22 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー 捕捉ビーズを用いる組み換えクローン化ｎａからの混入配列のアフイニテイ除去
WO1989000446A1 (en) * 1987-07-16 1989-01-26 E.I. Du Pont De Nemours And Company Affinity separating using immobilized flocculating reagents
US4913883A (en) * 1987-07-20 1990-04-03 Hitachi, Ltd. Particle agglutination immunoassay apparatus
US5102785A (en) * 1987-09-28 1992-04-07 E. I. Du Pont De Nemours And Company Method of gene mapping
FR2624613B1 (fr) * 1987-12-15 1994-08-26 Toledano Jacques Support microspherique de detection immuno-enzymatique, fluorescente, cheminumilescente ou radio-active de substances microdosees dans les milieux biologiques
JPH03504199A (ja) * 1988-05-10 1991-09-19 イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー 迅速な核酸検出法
US5147529A (en) * 1988-08-10 1992-09-15 E. I. Du Pont De Nemours And Company Method for automatically processing magnetic solid phase reagents
US4895453A (en) * 1988-08-24 1990-01-23 E. I. Du Pont De Nemours And Company Vortex mixer drive
US5104808A (en) * 1988-08-26 1992-04-14 Laska Paul F Method and apparatus for effecting a plurality of assays on a plurality of samples in an automatic analytical device
JPH02157655A (ja) * 1988-12-09 1990-06-18 Seiko Instr Inc 反応容器
IE900688A1 (en) * 1989-03-08 1991-02-13 Becton Dickinson Co Signal enhancement in magnetic immunoassay by inhibition of¹enzymatic catalysis
US5164297A (en) * 1990-05-03 1992-11-17 Advanced Magnetics Inc. Solvent mediated relaxation assay system
US5254460A (en) * 1990-05-03 1993-10-19 Advanced Magnetics, Inc. Solvent mediated relaxation assay system
US5665582A (en) * 1990-10-29 1997-09-09 Dekalb Genetics Corp. Isolation of biological materials
WO1992008133A1 (en) * 1990-10-29 1992-05-14 Dekalb Plant Genetics Isolation of biological materials using magnetic particles
US5128103A (en) * 1990-12-14 1992-07-07 E. I. Du Pont De Nemours And Company Apparatus for automatically processing magnetic solid phase reagents
US20060013729A1 (en) * 1991-02-14 2006-01-19 Glen Carey Fluid handling apparatus for an automated analyzer
US6436349B1 (en) * 1991-03-04 2002-08-20 Bayer Corporation Fluid handling apparatus for an automated analyzer
US6498037B1 (en) * 1991-03-04 2002-12-24 Bayer Corporation Method of handling reagents in a random access protocol
US5242833A (en) * 1991-03-20 1993-09-07 Reference Diagnostics, Inc. Lipid fractionation
US5104231A (en) * 1991-07-26 1992-04-14 E. I. Du Pont De Nemours And Company Vortex mixer drive
US5232665A (en) * 1991-07-26 1993-08-03 E. I. Du Pont De Nemours And Company Multi-linear automatic apparatus for processing immunoassays
EP0597951B1 (en) * 1991-07-26 1999-03-31 Dade Chemistry Systems Inc. An assay with signal detection in the presence of a suspended solid support
US5369006A (en) * 1991-08-20 1994-11-29 E. I. Du Pont De Nemours And Company Determination of CK isoenzymes and CK isoforms
DE19508772C2 (de) * 1995-03-01 1998-01-29 Schering Ag Verfahren und Verbindungen zur Detektion von Analyten mittels Remanenzmessung und deren Verwendung
US5776784A (en) * 1996-01-11 1998-07-07 Dade International Inc. Apparatus and method for reagent separation in a chemical analyzer
US6143578A (en) * 1996-05-10 2000-11-07 Bayer Corporation Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology
US5888835A (en) * 1996-05-10 1999-03-30 Chiron Diagnostics Corporation Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology
US5876935A (en) * 1997-01-08 1999-03-02 Dade Behring Inc. Luminescent specific binding assay
US6822782B2 (en) * 2001-05-15 2004-11-23 E Ink Corporation Electrophoretic particles and processes for the production thereof
US7247379B2 (en) 1997-08-28 2007-07-24 E Ink Corporation Electrophoretic particles, and processes for the production thereof
US7002728B2 (en) 1997-08-28 2006-02-21 E Ink Corporation Electrophoretic particles, and processes for the production thereof
US5990274A (en) * 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
US6231982B1 (en) 1997-12-10 2001-05-15 Dade Behring Inc. Particle reagents having reduced matrix effects and containing an aldehyde-reactive functional group
US6548264B1 (en) * 2000-05-17 2003-04-15 University Of Florida Coated nanoparticles
US6589629B1 (en) 2000-09-11 2003-07-08 Lucent Technologies Inc. Process for fabricating patterned, functionalized particles and article formed from particles
US7230750B2 (en) 2001-05-15 2007-06-12 E Ink Corporation Electrophoretic media and processes for the production thereof
US20100148385A1 (en) * 2001-05-15 2010-06-17 E Ink Corporation Electrophoretic media and processes for the production thereof
AU2003234196A1 (en) 2002-04-22 2003-11-03 University Of Florida Functionalized nanoparticles and methods of use
GB0215185D0 (en) 2002-07-01 2002-08-07 Genovision As Binding a target substance
US7189582B2 (en) 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
FR2898519B1 (fr) * 2006-03-20 2009-01-09 Commissariat Energie Atomique Nanoparticules notamment a structure coeur coquilles, enrobees
JP5391387B2 (ja) * 2007-03-09 2014-01-15 小川 一文 磁気感応性薬剤およびその製造方法
US7790401B2 (en) 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
US7910378B2 (en) 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
US8329424B2 (en) 2010-06-25 2012-12-11 Siemens Healthcare Diagnostics Reduction in false results in assay measurements
US9658218B2 (en) 2012-05-07 2017-05-23 Siemens Healthcare Diagnostics Inc. Determination of total analyte concentration
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9121859B2 (en) 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
WO2015089172A1 (en) 2013-12-13 2015-06-18 Siemens Healthcare Diagnostics Inc. Pretreatment agent in non-agglutination assays
AU2015208104B2 (en) * 2014-01-22 2019-02-14 Basf Corporation Silicon comprising polymer coated particles
CN106661114B (zh) 2014-06-27 2019-01-29 西门子医疗保健诊断公司 维生素d测定法中对维生素d差向异构体特异性的结合配偶体
KR102309377B1 (ko) 2014-06-27 2021-10-05 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 에피머에 특이적인 결합 파트너
ES2858555T3 (es) 2015-03-10 2021-09-30 Siemens Healthcare Diagnostics Inc Cuantificación de grupos funcionales sobre soportes sólidos.
US10310374B2 (en) 2016-08-18 2019-06-04 International Business Machines Corporation Repatternable nanoimprint lithography stamp

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3437502A (en) * 1968-03-28 1969-04-08 Du Pont Titanium dioxide pigment coated with silica and alumina
US3512930A (en) * 1969-05-07 1970-05-19 Du Pont Stabilized ferromagnetic chromium dioxide
US4068038A (en) * 1972-05-24 1978-01-10 Montecatini Edison S.P.A. Stabilized chromium dioxide compositions
GB1575805A (en) * 1976-03-12 1980-10-01 Technicon Instr Automatic diagnostic apparatus
DE2617809C2 (de) * 1976-04-23 1984-09-20 Basf Ag, 6700 Ludwigshafen Verfahren zur Stabilisierung von Chromdioxid-Magnetpigmenten und seine Verwendung
GB1582956A (en) * 1976-07-30 1981-01-21 Ici Ltd Composite magnetic particles
US4297337A (en) * 1979-04-13 1981-10-27 Corning Glass Works Solid-phase immunoassays using magnetic glass
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations

Also Published As

Publication number Publication date
ATE72050T1 (de) 1992-02-15
EP0240770A1 (en) 1987-10-14
US4661408A (en) 1987-04-28
GR3003647T3 (es) 1993-03-16
IE60178B1 (en) 1994-06-15
DK136787D0 (da) 1987-03-17
CA1289873C (en) 1991-10-01
JPS62226817A (ja) 1987-10-05
DE3776180D1 (de) 1992-03-05
DK136787A (da) 1987-09-19
JPH0463813B2 (es) 1992-10-13
EP0240770B1 (en) 1992-01-22
IE870658L (en) 1987-09-18

Similar Documents

Publication Publication Date Title
ES2032278T3 (es) Particulas de dioxido de cromo recubiertas.
DE3662085D1 (en) Magnetic coupling with integrated magnetic strain relief on the bearing
AU619979B2 (en) Depression of the flotation of silica or siliceous gangue in mineral flotation
ES2135929T3 (es) Lente de contacto multifocal y metodo para su produccion.
DE69318964D1 (de) Verbesserungen an oder bezüglich des Ringschienenteiles einer Ringbuchmechanik
DE69511936D1 (de) Zerkleinern mit feinteiligen Mahl-Medien
DE69417295D1 (de) Lager mit integriertem Messwertaufnehmer
DE3851573D1 (de) Reibungsloses Lager und mit einem solchen Lager ausgerüsteter Fahrzeugalternator.
DE59102459D1 (de) Blei-Zink-Borosilikatglas und Verwendung des Glases.
GB9313853D0 (en) Split-type bearing assembly
EP0142774A3 (en) Light diverting device
GB9225400D0 (en) Improvements in the manufacture of lightweight aggregates made with pulverised-fuel ash
EP0133702A3 (en) Providing hydrophobic surfaces on hydrophilic inorganic materials with metal glycolates
FR2714731B1 (fr) Compteur de vitesse tenant compte de paramètres d'un parcours.
DE69304505D1 (de) Lager für Lukendeckel oder ähnliches
DE69007467D1 (de) Doppelseitige Schleifscheibe mit interner Verstärkung.
GB2272849B (en) An arrangement for improving the processing properties of sand
FR2559127B1 (fr) Perfectionnements apportes aux structures de pietements pour conteneurs ou similaires et conteneurs equipes de tels systemes
FR2769349B1 (fr) Perfectionnement aux systemes d'equilibrage de roues
EP0744276A3 (de) Verfahren zur Herstellung eines integriert optischen Deckelbauteils, integriert optisches Deckelbauteil, Verfahren zur Herstellung eines integriert optischen Bauteils mit einem integriert optischen Deckelbauteil und integriert optisches Bauteil mit einem integriert optischen Deckelbauteil
ATE195993T1 (de) Kunststoff-lichtschacht mit abdeckung
TW302097U (en) Life compass with 36 trigrams according to The Book of Changes Life compass with trigram according to The Book of Changes
FR2570358B1 (fr) Atelier flexible pour l'assemblage et/ou l'usinage de pieces portees par des palettes circulantes
FR2709355B3 (fr) Lunettes anti sommeil.
MA21836A1 (fr) Abaissement de la flottation de la silice ou d'une gangue siliceuse dans la flottation de minerais .

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 240770

Country of ref document: ES