ES2027246T3 - Cuerpos moldeados a base de granulos. - Google Patents
Cuerpos moldeados a base de granulos.Info
- Publication number
- ES2027246T3 ES2027246T3 ES198787104716T ES87104716T ES2027246T3 ES 2027246 T3 ES2027246 T3 ES 2027246T3 ES 198787104716 T ES198787104716 T ES 198787104716T ES 87104716 T ES87104716 T ES 87104716T ES 2027246 T3 ES2027246 T3 ES 2027246T3
- Authority
- ES
- Spain
- Prior art keywords
- body molded
- molded bodies
- pellets
- delayed
- binder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/20—Extrusion means, e.g. for producing pharmaceutical forms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Encapsulation Of And Coatings For Semiconductor Or Solid State Devices (AREA)
- Perforating, Stamping-Out Or Severing By Means Other Than Cutting (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Clay, And Manufacture Of Mixtures Containing Clay Or Cement (AREA)
- Processing Of Solid Wastes (AREA)
Abstract
Procedimiento para la producción de un cuerpo moldeado a base de gránulos con liberación controlada y retardada de la sustancia activa, dentro de una matriz fusible a base de un agente aglutinante farmacológicamente compatible, caracterizado porque, o bien a) se cargan los gránulos en moldes y dentro de éstos se vierte a continuación el agente aglutinante; o bien b) los gránulos se revisten con el agente aglutinante, se cargan dentro de moldes y a continuación se calientan durante breve tiempo; o bien c) se mezclan los gránulos con el agente aglutinante, se cargan dentro de moldes y a continuación se calientan durante breve tiempo; o bien d) los gránulos, juntamente con el agente aglutinante y un agente propulsor, se cargan dentro de moldes y se calientan durante breve tiempo; de manera tal que resulta un cuerpo moldeado que se desintegra rápidamente en medios acuosos y que posee una estructura porosa.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863610878 DE3610878A1 (de) | 1986-04-01 | 1986-04-01 | Formlinge aus pellets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2027246T3 true ES2027246T3 (es) | 1992-06-01 |
Family
ID=6297660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198787104716T Expired - Lifetime ES2027246T3 (es) | 1986-04-01 | 1987-03-31 | Cuerpos moldeados a base de granulos. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0239983B1 (es) |
| JP (1) | JPS638327A (es) |
| KR (1) | KR950002881B1 (es) |
| AT (1) | ATE69547T1 (es) |
| AU (1) | AU600712B2 (es) |
| CA (1) | CA1314480C (es) |
| DE (2) | DE3610878A1 (es) |
| DK (1) | DK162887A (es) |
| ES (1) | ES2027246T3 (es) |
| FI (1) | FI94313C (es) |
| GR (1) | GR3003661T3 (es) |
| IL (1) | IL82065A0 (es) |
| MX (1) | MX5814A (es) |
| NO (1) | NO175513C (es) |
| NZ (1) | NZ219823A (es) |
| PT (1) | PT84604B (es) |
| ZA (1) | ZA872326B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW407502U (en) * | 1991-09-10 | 2000-10-01 | Takeda Chemical Industries Ltd | Divisible tablet |
| GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| AUPP279698A0 (en) * | 1998-04-03 | 1998-04-30 | Sunscape Developments Limited | Sustained release formulation |
| DE19918325A1 (de) | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
| US7217381B2 (en) | 2001-09-28 | 2007-05-15 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
| US7838026B2 (en) | 2001-09-28 | 2010-11-23 | Mcneil-Ppc, Inc. | Burst-release polymer composition and dosage forms comprising the same |
| CN100408029C (zh) | 2001-09-28 | 2008-08-06 | 麦克内尔-Ppc股份有限公司 | 有镶嵌部分的组合剂型 |
| US6982094B2 (en) | 2001-09-28 | 2006-01-03 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
| US7122143B2 (en) | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
| US6837696B2 (en) | 2001-09-28 | 2005-01-04 | Mcneil-Ppc, Inc. | Apparatus for manufacturing dosage forms |
| US7807197B2 (en) | 2002-09-28 | 2010-10-05 | Mcneil-Ppc, Inc. | Composite dosage forms having an inlaid portion |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2996431A (en) * | 1953-12-16 | 1961-08-15 | Barry Richard Henry | Friable tablet and process for manufacturing same |
| FR1540950A (fr) * | 1967-04-27 | 1968-10-04 | Procédé de conditionnement de substances médicamenteuses absorbables par voie buccale | |
| DE1766546C3 (de) * | 1968-06-11 | 1974-11-28 | Karl Gunnar Lidingoe Eriksson | Verfahren zum Herstellen von festen dragee- oder tablettenförmigen Arzneimittelzubereitungen |
| NL6808619A (es) * | 1968-06-19 | 1969-12-23 | ||
| DK123806B (da) * | 1970-06-08 | 1972-08-07 | Pharmacia As | Fremgangsmåde til fremstilling af tabletter eller piller med langsom afgivelse af et aktivt stof. |
| GB1425550A (en) * | 1973-04-25 | 1976-02-18 | Alza Corp | Device for releasing active agent and process for producing the same |
| DE2336218C3 (de) * | 1973-07-17 | 1985-11-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Orale Arzneiform |
| SE414386B (sv) * | 1976-03-10 | 1980-07-28 | Aco Laekemedel Ab | Sett att framstella och samtidigt forpacka farmaceutiska dosenheter |
| DE2620456A1 (de) * | 1976-05-08 | 1977-11-10 | Enterofagos Gmbh | Galenische zubereitung in tablettenform |
| US4258027A (en) * | 1979-03-26 | 1981-03-24 | Mead Johnson & Company | Multi-fractionable tablet structure |
| DE3532692A1 (de) * | 1985-09-13 | 1987-03-19 | Boehringer Mannheim Gmbh | Verfahren zum herstellen von tabletten aus pellets |
-
1986
- 1986-04-01 DE DE19863610878 patent/DE3610878A1/de not_active Ceased
-
1987
- 1987-03-30 KR KR1019870002929A patent/KR950002881B1/ko not_active IP Right Cessation
- 1987-03-30 FI FI871378A patent/FI94313C/fi not_active IP Right Cessation
- 1987-03-31 ZA ZA872326A patent/ZA872326B/xx unknown
- 1987-03-31 DK DK162887A patent/DK162887A/da not_active IP Right Cessation
- 1987-03-31 EP EP87104716A patent/EP0239983B1/de not_active Expired - Lifetime
- 1987-03-31 MX MX581487A patent/MX5814A/es unknown
- 1987-03-31 IL IL82065A patent/IL82065A0/xx not_active IP Right Cessation
- 1987-03-31 NO NO871350A patent/NO175513C/no unknown
- 1987-03-31 DE DE8787104716T patent/DE3774601D1/de not_active Expired - Lifetime
- 1987-03-31 JP JP62079534A patent/JPS638327A/ja active Pending
- 1987-03-31 NZ NZ219823A patent/NZ219823A/xx unknown
- 1987-03-31 AT AT87104716T patent/ATE69547T1/de not_active IP Right Cessation
- 1987-03-31 CA CA000533393A patent/CA1314480C/en not_active Expired - Fee Related
- 1987-03-31 ES ES198787104716T patent/ES2027246T3/es not_active Expired - Lifetime
- 1987-04-01 PT PT84604A patent/PT84604B/pt not_active IP Right Cessation
- 1987-04-01 AU AU70956/87A patent/AU600712B2/en not_active Ceased
-
1992
- 1992-01-27 GR GR920400090T patent/GR3003661T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI94313C (fi) | 1995-08-25 |
| EP0239983A2 (de) | 1987-10-07 |
| PT84604B (pt) | 1989-11-30 |
| NO871350L (no) | 1987-10-02 |
| ZA872326B (en) | 1988-12-28 |
| FI94313B (fi) | 1995-05-15 |
| MX5814A (es) | 1993-10-01 |
| DE3774601D1 (de) | 1992-01-02 |
| NO175513B (no) | 1994-07-18 |
| NZ219823A (en) | 1990-05-28 |
| IL82065A0 (en) | 1987-10-20 |
| DK162887A (da) | 1987-10-02 |
| NO175513C (no) | 1994-10-26 |
| JPS638327A (ja) | 1988-01-14 |
| EP0239983B1 (de) | 1991-11-21 |
| KR950002881B1 (ko) | 1995-03-28 |
| FI871378A (fi) | 1987-10-02 |
| GR3003661T3 (es) | 1993-03-16 |
| FI871378A0 (fi) | 1987-03-30 |
| EP0239983A3 (en) | 1988-11-30 |
| ATE69547T1 (de) | 1991-12-15 |
| AU600712B2 (en) | 1990-08-23 |
| KR870009719A (ko) | 1987-11-30 |
| PT84604A (de) | 1987-05-01 |
| DE3610878A1 (de) | 1987-10-08 |
| NO871350D0 (no) | 1987-03-31 |
| CA1314480C (en) | 1993-03-16 |
| AU7095687A (en) | 1987-10-08 |
| DK162887D0 (da) | 1987-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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