ES2018638A6 - Procedimiento para producir microesferas mediante reticulacion de pro-teinas. - Google Patents

Procedimiento para producir microesferas mediante reticulacion de pro-teinas.

Info

Publication number
ES2018638A6
ES2018638A6 ES8902870A ES8902870A ES2018638A6 ES 2018638 A6 ES2018638 A6 ES 2018638A6 ES 8902870 A ES8902870 A ES 8902870A ES 8902870 A ES8902870 A ES 8902870A ES 2018638 A6 ES2018638 A6 ES 2018638A6
Authority
ES
Spain
Prior art keywords
crosslinking
proteins
microspheres
production
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8902870A
Other languages
English (en)
Inventor
Josiane Allec
Florence Godail
Jean-Claude Jamoulle
Braham Shroot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Centre International de Recherches Dermatologiques Galderma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre International de Recherches Dermatologiques Galderma filed Critical Centre International de Recherches Dermatologiques Galderma
Publication of ES2018638A6 publication Critical patent/ES2018638A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA PRODUCIR MICROESFERAS MEDIANTE RETICULACION DE PROTEINAS. CONSISTE EN REALIZAR LA RETICULACION EN UNA EMULSION CUYA FASE CONTINUA ESTA CONSTITUIDA POR UN DISOLVENTE INERTE AL QUE SE AÑADE UN AGENTE TENSIOACTIVO. Y CUYA FASE DISCONTINUA COMPRENDE UNA FASE LIQUIDA HIDROFILA QUE CONTIENE AL MENOS UNA PROTEINA, Y AÑADIR A LA EMULSION UNA CARBODIIMIDA PARA ACTIVAR LA RETICULACION Y OBTENER UN PRECIPITADO DE MICROESFERAS, TRAS LO CUAL SE SEPARA Y SE LAVA DICHO PRECIPITADO. LAS MICROESFERAS PRODUCIDAS SON UTILES PARA ACONDICIONAR COMPUESTOS DE ACTIVIDAD FARMACEUTICA O COSMETICA.
ES8902870A 1988-08-17 1989-08-16 Procedimiento para producir microesferas mediante reticulacion de pro-teinas. Expired - Lifetime ES2018638A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8810942A FR2635459B1 (fr) 1988-08-17 1988-08-17 Procede de fabrication de microspheres par reticulation de proteines, microspheres ainsi obtenues et leurs utilisations

Publications (1)

Publication Number Publication Date
ES2018638A6 true ES2018638A6 (es) 1991-04-16

Family

ID=9369356

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8902870A Expired - Lifetime ES2018638A6 (es) 1988-08-17 1989-08-16 Procedimiento para producir microesferas mediante reticulacion de pro-teinas.

Country Status (6)

Country Link
JP (1) JPH02167222A (es)
DE (1) DE3927073A1 (es)
ES (1) ES2018638A6 (es)
FR (1) FR2635459B1 (es)
GB (1) GB2224258B (es)
IT (1) IT1232917B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5271961A (en) * 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
DE69117059T2 (de) * 1990-06-19 1996-06-27 Mars Inc Fettersatz und verfahren zur herstellung von organischen mikrokugeln
WO1995005161A1 (en) * 1993-08-13 1995-02-23 Vitaphore Corporation Hydrogel-based microsphere drug delivery systems
US7521068B2 (en) 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
PT1471887E (pt) * 2002-02-04 2010-07-16 Elan Pharma Int Ltd ComposiãŽes de nanopartculas com lisozima como um estabilizador superficial
JP5057501B2 (ja) * 2005-11-25 2012-10-24 株式会社パイロットコーポレーション マイクロカプセルの製造法ならびにマイクロカプセル及びそれを用いた表示媒体
CN108495709B (zh) * 2016-01-25 2021-09-03 三得利控股株式会社 含有功能性物质的胶囊及其制造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1077842A (en) * 1975-10-09 1980-05-20 Minnesota Mining And Manufacturing Company Albumin medicament carrier system
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal
JPS58162595A (ja) * 1982-03-19 1983-09-27 Green Cross Corp:The 徐放性アルブミン複合体の製法
IL74715A0 (en) * 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
GB2160312B (en) * 1984-04-13 1987-09-16 South African Inventions Adjuvant for immunisation
WO1986004232A1 (en) * 1985-01-18 1986-07-31 Cooper-Lipotech, Inc. Liposome composition and method

Also Published As

Publication number Publication date
FR2635459B1 (fr) 1992-06-19
DE3927073A1 (de) 1990-02-22
GB2224258A (en) 1990-05-02
IT1232917B (it) 1992-03-05
JPH02167222A (ja) 1990-06-27
GB2224258B (en) 1991-12-11
GB8918720D0 (en) 1989-09-27
FR2635459A1 (fr) 1990-02-23
IT8967705A0 (it) 1989-08-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001102