ES2017805A6 - Production of preparation of aluminum salt of sucrose sulfuric acid ester - Google Patents
Production of preparation of aluminum salt of sucrose sulfuric acid esterInfo
- Publication number
- ES2017805A6 ES2017805A6 ES8701280A ES8701280A ES2017805A6 ES 2017805 A6 ES2017805 A6 ES 2017805A6 ES 8701280 A ES8701280 A ES 8701280A ES 8701280 A ES8701280 A ES 8701280A ES 2017805 A6 ES2017805 A6 ES 2017805A6
- Authority
- ES
- Spain
- Prior art keywords
- sulfuric acid
- acid ester
- preparation
- aluminum salt
- polyethylene glycol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229930006000 Sucrose Natural products 0.000 title abstract 4
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 title abstract 4
- 239000005720 sucrose Substances 0.000 title abstract 4
- -1 sucrose sulfuric acid ester Chemical class 0.000 title abstract 4
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 title abstract 4
- 239000002202 Polyethylene glycol Substances 0.000 abstract 4
- 229920001223 polyethylene glycol Polymers 0.000 abstract 4
- 208000025865 Ulcer Diseases 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 231100000397 ulcer Toxicity 0.000 abstract 2
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 208000011906 peptic ulcer disease Diseases 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Abstract
PURPOSE:To obtain the titled preparation for treating peptic ulcer, having raised disintegration and dispersibility and high utility as drug, containing an aluminum salt of sucrose sulfuric acid ester and polyethylene glycol. CONSTITUTION:A preparation containing an aluminum salt of sucrose sulfuric acid ester and polyethylene glycol. Disintegration and dispersibility of aluminum salt of sucrose sulfuric acid ester (A for short) are raised by the use of polyethylene glycol and utility as drug is also elevated. Since A is insoluble in water, disintegration and dispersibility are raised to give effective bond to an ulcer site. The amount of the polyethylene glycol added is >=0.1 (W/W) based on A. When the preparation is orally administered, A is effectively bonded to the ulcer site.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9990186 | 1986-04-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2017805A6 true ES2017805A6 (en) | 1991-03-01 |
Family
ID=14259677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8701280A Expired - Lifetime ES2017805A6 (en) | 1986-04-30 | 1987-04-29 | Production of preparation of aluminum salt of sucrose sulfuric acid ester |
Country Status (9)
Country | Link |
---|---|
JP (1) | JP2542210B2 (en) |
DE (1) | DE3714159C2 (en) |
DK (1) | DK167735B1 (en) |
ES (1) | ES2017805A6 (en) |
FI (1) | FI89457C (en) |
FR (1) | FR2598084B1 (en) |
IT (1) | IT1208416B (en) |
NO (1) | NO174085C (en) |
SE (1) | SE503233C2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2112765A1 (en) * | 1995-08-02 | 1998-04-01 | Cantabria Ind Farmaceutica Sa | Radiological, gastrointestinal contrast formulations |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2735559B2 (en) * | 1988-03-02 | 1998-04-02 | 中外製薬株式会社 | Suspension |
BR9507533A (en) * | 1994-04-26 | 1997-09-02 | Chugai Pharmaceutical Co Ltd | Fused granulated sucralfate preparations and a process for their production |
KR19980701891A (en) * | 1995-02-02 | 1998-06-25 | 나가야마 나오루 | Sucralate formulations |
TW201132646A (en) * | 2010-02-22 | 2011-10-01 | Daiichi Sankyo Co Ltd | Oral solid extended release dosage form |
TW201141544A (en) | 2010-02-22 | 2011-12-01 | Daiichi Sankyo Co Ltd | Oral solid extended release dosage form |
KR102127625B1 (en) | 2012-09-03 | 2020-06-29 | 다이이찌 산쿄 가부시키가이샤 | Hydromorphone hydrochloride-containing oral sustained-release pharmaceutical composition |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3430809A1 (en) * | 1984-08-22 | 1986-03-06 | Merck Patent Gmbh, 6100 Darmstadt | SUCRALFAT SUSPENSION |
-
1987
- 1987-04-28 NO NO871759A patent/NO174085C/en unknown
- 1987-04-28 DE DE3714159A patent/DE3714159C2/en not_active Expired - Lifetime
- 1987-04-28 FI FI871852A patent/FI89457C/en not_active IP Right Cessation
- 1987-04-29 IT IT8767365A patent/IT1208416B/en active
- 1987-04-29 ES ES8701280A patent/ES2017805A6/en not_active Expired - Lifetime
- 1987-04-29 SE SE8701787A patent/SE503233C2/en not_active IP Right Cessation
- 1987-04-29 DK DK218587A patent/DK167735B1/en not_active IP Right Cessation
- 1987-04-30 JP JP62104612A patent/JP2542210B2/en not_active Expired - Lifetime
- 1987-04-30 FR FR878706196A patent/FR2598084B1/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2112765A1 (en) * | 1995-08-02 | 1998-04-01 | Cantabria Ind Farmaceutica Sa | Radiological, gastrointestinal contrast formulations |
Also Published As
Publication number | Publication date |
---|---|
NO174085B (en) | 1993-12-06 |
DK218587D0 (en) | 1987-04-29 |
FI871852A (en) | 1987-10-31 |
FR2598084B1 (en) | 1991-04-26 |
FR2598084A1 (en) | 1987-11-06 |
FI89457C (en) | 1993-10-11 |
NO174085C (en) | 1994-03-16 |
IT1208416B (en) | 1989-06-12 |
SE8701787D0 (en) | 1987-04-29 |
DK218587A (en) | 1987-10-31 |
NO871759L (en) | 1987-11-02 |
JPS63107933A (en) | 1988-05-12 |
DE3714159A1 (en) | 1987-11-05 |
SE8701787L (en) | 1987-10-31 |
NO871759D0 (en) | 1987-04-28 |
DE3714159C2 (en) | 1996-09-19 |
FI89457B (en) | 1993-06-30 |
DK167735B1 (en) | 1993-12-13 |
JP2542210B2 (en) | 1996-10-09 |
SE503233C2 (en) | 1996-04-22 |
IT8767365A0 (en) | 1987-04-29 |
FI871852A0 (en) | 1987-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20070430 |