ES2016957B3 - Procedimiento para la obtencion de n,n'-diarilreas. - Google Patents

Procedimiento para la obtencion de n,n'-diarilreas.

Info

Publication number
ES2016957B3
ES2016957B3 ES87114817T ES87114817T ES2016957B3 ES 2016957 B3 ES2016957 B3 ES 2016957B3 ES 87114817 T ES87114817 T ES 87114817T ES 87114817 T ES87114817 T ES 87114817T ES 2016957 B3 ES2016957 B3 ES 2016957B3
Authority
ES
Spain
Prior art keywords
diarilreas
procedure
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87114817T
Other languages
English (en)
Spanish (es)
Inventor
Wolfram Kissener
Joachim Franke
Helmut Fiege
Karlfried Wedemeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2016957B3 publication Critical patent/ES2016957B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES87114817T 1986-10-24 1987-10-10 Procedimiento para la obtencion de n,n'-diarilreas. Expired - Lifetime ES2016957B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863636190 DE3636190A1 (de) 1986-10-24 1986-10-24 Verfahren zur herstellung von n,n-diaryl-harnstoffen

Publications (1)

Publication Number Publication Date
ES2016957B3 true ES2016957B3 (es) 1990-12-16

Family

ID=6312378

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87114817T Expired - Lifetime ES2016957B3 (es) 1986-10-24 1987-10-10 Procedimiento para la obtencion de n,n'-diarilreas.

Country Status (7)

Country Link
US (1) US4820871A (index.php)
EP (1) EP0264752B1 (index.php)
JP (1) JPS63122660A (index.php)
CA (1) CA1295340C (index.php)
DE (2) DE3636190A1 (index.php)
DK (1) DK555687A (index.php)
ES (1) ES2016957B3 (index.php)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248755A (en) * 1989-07-28 1993-09-28 Chemie Linz Gesellschaft M.B.H. Process for the preparation of asymmetrically substituted ureas, carbamates or thiocarbamates
ES2066049T3 (es) * 1989-07-28 1995-03-01 Chemie Linz Gmbh Procedimiento para la obtencion de ureas asimetricamente substituidas.
US5220061A (en) * 1992-02-07 1993-06-15 Arco Chemical Technology, L.P. Selective process for the preparation of diphenylmethane bis-(dialkyl ureas
JP3372436B2 (ja) * 1996-11-28 2003-02-04 オークマ株式会社 インバータの制御装置
US6344476B1 (en) 1997-05-23 2002-02-05 Bayer Corporation Inhibition of p38 kinase activity by aryl ureas
US20080300281A1 (en) * 1997-12-22 2008-12-04 Jacques Dumas Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
US7517880B2 (en) 1997-12-22 2009-04-14 Bayer Pharmaceuticals Corporation Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
US7329670B1 (en) 1997-12-22 2008-02-12 Bayer Pharmaceuticals Corporation Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
US20080269265A1 (en) * 1998-12-22 2008-10-30 Scott Miller Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
ME00275B (me) * 1999-01-13 2011-02-10 Bayer Corp ω-KARBOKSIARIL SUPSTITUISANI DIFENIL KARBAMIDI KAO INHIBITORI RAF KINAZE
EP1140840B1 (en) 1999-01-13 2006-03-22 Bayer Pharmaceuticals Corp. -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US8124630B2 (en) * 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7928239B2 (en) 1999-01-13 2011-04-19 Bayer Healthcare Llc Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
ATE556713T1 (de) * 1999-01-13 2012-05-15 Bayer Healthcare Llc Omega-carboxyarylsubstituierte-diphenyl- harnstoffe als p38-kinasehemmer
CA2383086A1 (en) 1999-09-08 2001-03-15 Joseph P. Steiner Non-peptidic cyclophilin binding compounds and their use
US7235576B1 (en) 2001-01-12 2007-06-26 Bayer Pharmaceuticals Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
MXPA03006666A (es) 2001-01-25 2004-05-31 Guilford Pharm Inc Compuestos de union de ciclofilina carbociclicos trisubstituidos y su uso.
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
DE60216139T3 (de) * 2001-12-03 2018-11-15 Bayer Healthcare Llc Arylharnstoff-verbindungen in kombination mit anderen zytostatisch oder zytotoxisch wirksamen stoffen zur behandlungen menschlicher krebserkrankungen
US20080108672A1 (en) * 2002-01-11 2008-05-08 Bernd Riedl Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
AU2003210969A1 (en) * 2002-02-11 2003-09-04 Bayer Corporation Aryl ureas with raf kinase and angiogenesis inhibiting activity
WO2003068229A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
SI1580188T1 (sl) * 2002-02-11 2012-02-29 Bayer Healthcare Llc Aril sečnine kot kinazni inhibitorji
AU2003209116A1 (en) * 2002-02-11 2003-09-04 Bayer Pharmaceuticals Corporation Aryl ureas with angiogenesis inhibiting activity
US7557129B2 (en) 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
PT1636585E (pt) * 2003-05-20 2008-03-27 Bayer Pharmaceuticals Corp Diarilureias com actividade inibidora de cinase
PL1663978T3 (pl) * 2003-07-23 2008-04-30 Bayer Healthcare Llc Fluoropodstawiony omega-karboksyarylodifenylomocznik do leczenia i profilaktyki chorób i stanów
US7838524B2 (en) * 2004-04-30 2010-11-23 Bayer Healthcare Llc Substituted pyrazolyl urea derivatives useful in the treatment of cancer
CN102924336A (zh) * 2012-09-28 2013-02-13 黎明化工研究设计院有限责任公司 一种制备n-甲基-n’，n’-二苯基脲的方法
CN103232371B (zh) * 2013-04-26 2014-11-26 黎明化工研究设计院有限责任公司 一种制备n-甲基-n’，n’-二苯基脲的方法
EP3652230A1 (de) * 2017-07-11 2020-05-20 Covestro Deutschland AG Weichschaumstoff mit halogenfreiem flammschutz
KR102790008B1 (ko) * 2018-12-07 2025-04-07 다우 글로벌 테크놀로지스 엘엘씨 모노이소시아네이트를 요소로 전환하는 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2683727A (en) * 1954-07-13 Secondary aromatic amines
CH513134A (de) * 1968-06-10 1971-09-30 Bayer Ag Verfahren zur Herstellung von N-Arylharnstoffen
JPS5419937A (en) * 1977-07-12 1979-02-15 Showa Denko Kk Preparation of urea substitution product
DE2928485A1 (de) * 1979-07-14 1981-01-29 Bayer Ag Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
WO1981002156A1 (en) * 1980-01-25 1981-08-06 Reanal Finomvegyszergyar Process for the preparation of n-aryl-n'-(mono-or disubstiuted)-urea derivatives
IT1137177B (it) * 1981-06-02 1986-09-03 Anic Spa Processo per la preparazione di uree asimmetriche a partire da uretani ed ammine
US4473579A (en) * 1982-01-26 1984-09-25 American Cyanamid Company Antiatherosclerotic tetrasubstituted ureas and thioureas

Also Published As

Publication number Publication date
DK555687D0 (da) 1987-10-23
EP0264752B1 (de) 1990-08-29
US4820871A (en) 1989-04-11
JPH0360817B2 (index.php) 1991-09-17
DE3764602D1 (de) 1990-10-04
CA1295340C (en) 1992-02-04
JPS63122660A (ja) 1988-05-26
EP0264752A1 (de) 1988-04-27
DK555687A (da) 1988-04-25
DE3636190A1 (de) 1988-04-28

Similar Documents

Publication Publication Date Title
ES2016957B3 (es) Procedimiento para la obtencion de n,n'-diarilreas.
DE3764686D1 (de) N,n'-dihalo-2-imidazolidinone.
FI874959L (fi) Tvaettmedelskomposition, som innehaoller etylendiamin-n,n'-dibaernstenssyra.
ES540597A0 (es) Procedimiento para la obtencion de piridonas.
DE3783669D1 (de) Alpha-aryl-alpha-phenethyl-1h-1,2,4-triazol-1-propan-nitrile.
ES2032299T3 (es) Procedimiento para obtener derivados de metil-penicilina 3-beta-sustituida.
ES2007557B3 (es) Procedimiento para la preparacion de (2,2)- paraciclofano.
FI875619A7 (fi) 6-benzoxazinyl- och 6-benzotiazonyl-2,3,4,5-tetrahydropyridazin-3-oner.
ES2024453B3 (es) Derivados de 1,2,3,6-tetrahidro-5-nitropirimidina.
ES554759A0 (es) Procedimiento para la obtencion de 1,3,5-triazintrionas
ES557639A0 (es) Procedimiento para la obtencion de 2,2-difluoro-4-amino-1,3-benzodioxol
ES2021411B3 (es) Proceso para la preparacion de (2,2) paraciclofano.
ES517281A0 (es) Procedimiento para la obtencion de 4,4'-diisocianatodifenilmetano.
ES510730A0 (es) "procedimiento para la preparacion de (2,2')-disulfuros de ditiazolilo".
ES2021105B3 (es) Procedimiento para la obtencion de 5-amino-4,6-dihalogeno piridinas.
ES2019098B3 (es) Procedimiento para preparar halogenuros de 1-metil-3,5,7-triaza-1-azoniatriciclodecano.
IT1236969B (it) Procedimento di preparazione di 3-ciano-3,5,5'-trimetil-1-cicloesanone.
ES509761A0 (es) "procedimiento para la preparacion de 1,2 benzisoxazoloxietilaminas".
ES503653A0 (es) Procedimiento para la obtencion de 2,4-dioxa-7,10-metano-espiro s',s-undecanos.
ES544459A0 (es) Procedimiento para la obtencion de benzo -c- -1,8-naftiridi-nas
ES514224A0 (es) "procedimiento para la preparacion de 2,4-diamino-(3,5-dimetoxi-4-metoxietoxibenzil)-pirimidina".
ES540132A0 (es) Un procedimiento para la preparacion de 1,4-aminoalquilamino-9-h-tioxaten-9-onas.
ES549429A0 (es) Procedimiento para la obtencion de acemetacina.
MX5413A (es) Procedimiento para la preparacion de n-benzoil-n'-fenilureas.
ES2016651B3 (es) Proceso mejorado para la preparacion de n,n'tetratiodimorfolinas.