ES2013046A6 - Procedure for preparing a protein labelled with a metallic radionuclide - Google Patents

Procedure for preparing a protein labelled with a metallic radionuclide

Info

Publication number
ES2013046A6
ES2013046A6 ES8900646A ES8900646A ES2013046A6 ES 2013046 A6 ES2013046 A6 ES 2013046A6 ES 8900646 A ES8900646 A ES 8900646A ES 8900646 A ES8900646 A ES 8900646A ES 2013046 A6 ES2013046 A6 ES 2013046A6
Authority
ES
Spain
Prior art keywords
protein
radionuclide
preparing
procedure
labelled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8900646A
Other languages
Spanish (es)
Inventor
Wilhemus T Goedemans
Karel J Panek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of ES2013046A6 publication Critical patent/ES2013046A6/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Abstract

Procedure for preparing a protein labelled with a metallic radionuclide. It involves reacting a protein with an agent to bind the radionuclide to the protein, thus forming a protein conjugate, and then complexing the radionuclide with a conjugate so formed in order to form a radionuclide complex. The binding agent consists of a thio compound of the formula Y-R-S-X, in which X, R and Y are defined as in the description, or of a cyclic condensation product of said thio compound. The protein so labelled can be used for diagnostic or therapeutic purposes in the treatment of tumours.
ES8900646A 1988-07-08 1989-02-22 Procedure for preparing a protein labelled with a metallic radionuclide Expired - Fee Related ES2013046A6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8801728 1988-07-08
NL8802408 1988-09-30

Publications (1)

Publication Number Publication Date
ES2013046A6 true ES2013046A6 (en) 1990-04-16

Family

ID=26646399

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8900646A Expired - Fee Related ES2013046A6 (en) 1988-07-08 1989-02-22 Procedure for preparing a protein labelled with a metallic radionuclide

Country Status (2)

Country Link
JP (1) JPH03505726A (en)
ES (1) ES2013046A6 (en)

Also Published As

Publication number Publication date
JPH03505726A (en) 1991-12-12

Similar Documents

Publication Publication Date Title
ES8706965A1 (en) Method of forming a metal chelate protein conjugate.
SG91685G (en) Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of cancer,as well as a medicine thus formed
EP0417870A3 (en) Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy
KR0137930B1 (en) Process for preparing isothiocyanato functionalized metal complexes
ES8205231A1 (en) Platinum(IV)-diamine complexes, a process for the preparation thereof, a process for the preparation of a medicine using such a platinum(IV)-diamine complex for the treatment of malignant tumors in mice
ES8405071A1 (en) Covalent conjugates of an enzyme and an antibody, and medicinal compositions containing these conjugates.
HU911928D0 (en) Process for the production of chelates and its complexes containing orto ligating functional group, and the medical preparations containing thereof
ZA837857B (en) Platinum-diamine complexes,a process for the preparation thereof and a process for the preparation of a medical composition using such a complex for the treatment of cancer
AU6501794A (en) Chelating agents of the type xn1s1o1 for radioactive isotopes, metal complexes thereof, and their use in diagnosis and therapy
SG48889A1 (en) Bicycle-polyamacrocyclocarboxylic acid complexes conjugates preparation and use as contrast agents
IL79260A (en) Process and composition for activation of immune response cells to be used in the treatment of cancer,non-malignant tumors,infections,and immune deficiencies
ES2013046A6 (en) Procedure for preparing a protein labelled with a metallic radionuclide
EP0341318A4 (en) Novel platinum (ii) complex, process for preparing the same, and therapeutic agent for malignant tumor

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20011110