ES2006672A6 - Procedimiento para preparar formulaciones farmaceuticas a base de 3'-azido-nucleosidos. - Google Patents

Procedimiento para preparar formulaciones farmaceuticas a base de 3'-azido-nucleosidos.

Info

Publication number
ES2006672A6
ES2006672A6 ES8801870A ES8801870A ES2006672A6 ES 2006672 A6 ES2006672 A6 ES 2006672A6 ES 8801870 A ES8801870 A ES 8801870A ES 8801870 A ES8801870 A ES 8801870A ES 2006672 A6 ES2006672 A6 ES 2006672A6
Authority
ES
Spain
Prior art keywords
residue
configuration
viral
uridine
bacterial infections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8801870A
Other languages
English (en)
Inventor
Janet Litster Rideout
David Walter Barry
Sandra Nusinoof Lehrman
Clair Martha Heider St
Phillip Allen Furman
George Andrew Freeman
Thomas Paul Zimmerman
Gerald Wolberg
Paulo M Miranda
Sammy Ray Shaver
Geoffrey White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/776,899 external-priority patent/US4724232A/en
Priority claimed from GB858523878A external-priority patent/GB8523878D0/en
Priority claimed from GB868608272A external-priority patent/GB8608272D0/en
Priority claimed from GB868615322A external-priority patent/GB8615322D0/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES2006672A6 publication Critical patent/ES2006672A6/es
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR FORMULACIONES FARMACEUTICAS A BASE DE 3''-AZIDO-NUCLEOSIDOS DE FORMULA: (DONDE B ES UNA BASE DE PURINA O PIRMIDINA UNIDA EN LA POSICION 9 O 1, RESPECTIVAMENTE), EN EL QUE SE HACE REACCIONAR UN COMPUESTO DE FORMULA (DONDE B ES UNA BASE DE PURINA O PIRIMIDINA DISTINTA DE TIMINA, UNIDA EN LA POSICION 9 O 1, RESPECTIVAMENTE, Y M REPRESENTA UN GRUPO PRECURSOS PARA EL GRUPO AZIDO DE LA POSICION 3''), CON UN AGENTE O EN CONDICIONES QUE SIRVAN PARA CONVERTIR DICHO GRUPO PRECURSOR EN EL GRUPO AZIDO DESEADO, Y EL COMPUESTO RESULTANTE DE FORMULA (I)A SE PONE EN ASOCIACION CON UN SEGUNDO AGENTE TERAPEUTICO Y/O UN VEHICULO FARMACEUTICAMENTE ACEPTABLE. LAS COMPOSICIONES OBTENIDAS SON PARTICULARMENTE UTILES PARA EL TRATAMIENTO Y PROFILAXIS BACTERIANAS GRAM-NEGATIVAS E INFECCIONES POR RETROVIRUS, ESPECIALMENTE EL SIDA.
ES8801870A 1985-09-17 1988-06-16 Procedimiento para preparar formulaciones farmaceuticas a base de 3'-azido-nucleosidos. Expired ES2006672A6 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US06/776,899 US4724232A (en) 1985-03-16 1985-09-17 Treatment of human viral infections
GB858523878A GB8523878D0 (en) 1985-09-27 1985-09-27 Therapeutic compounds
GB868608272A GB8608272D0 (en) 1986-04-04 1986-04-04 Antiviral combination
US87779686A 1986-06-23 1986-06-23
GB868615322A GB8615322D0 (en) 1986-06-23 1986-06-23 Antiviral combinations

Publications (1)

Publication Number Publication Date
ES2006672A6 true ES2006672A6 (es) 1989-05-01

Family

ID=27516614

Family Applications (2)

Application Number Title Priority Date Filing Date
ES8601910A Expired ES2002342A6 (es) 1985-09-17 1986-09-15 Procedimiento para la preparacion de 3'-azido-nucleosidos
ES8801870A Expired ES2006672A6 (es) 1985-09-17 1988-06-16 Procedimiento para preparar formulaciones farmaceuticas a base de 3'-azido-nucleosidos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES8601910A Expired ES2002342A6 (es) 1985-09-17 1986-09-15 Procedimiento para la preparacion de 3'-azido-nucleosidos

Country Status (2)

Country Link
ES (2) ES2002342A6 (es)
MC (1) MC1766A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections
US11903916B2 (en) 2020-04-10 2024-02-20 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections

Also Published As

Publication number Publication date
MC1766A1 (fr) 1987-07-17
ES2002342A6 (es) 1988-08-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20100528