ES2005249A6 - Un procedimiento para preparar derivados de benzoguanamina. - Google Patents
Un procedimiento para preparar derivados de benzoguanamina.Info
- Publication number
- ES2005249A6 ES2005249A6 ES8701678A ES8701678A ES2005249A6 ES 2005249 A6 ES2005249 A6 ES 2005249A6 ES 8701678 A ES8701678 A ES 8701678A ES 8701678 A ES8701678 A ES 8701678A ES 2005249 A6 ES2005249 A6 ES 2005249A6
- Authority
- ES
- Spain
- Prior art keywords
- tert
- reaction
- mol
- alcohol
- kept
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GZVHEAJQGPRDLQ-UHFFFAOYSA-N 6-phenyl-1,3,5-triazine-2,4-diamine Chemical class NC1=NC(N)=NC(C=2C=CC=CC=2)=N1 GZVHEAJQGPRDLQ-UHFFFAOYSA-N 0.000 title abstract 2
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 abstract 5
- MSXVEPNJUHWQHW-UHFFFAOYSA-N 2-methylbutan-2-ol Chemical compound CCC(C)(C)O MSXVEPNJUHWQHW-UHFFFAOYSA-N 0.000 abstract 3
- LNGWRTKJZCBXGT-UHFFFAOYSA-N 2,5-dichlorobenzonitrile Chemical compound ClC1=CC=C(Cl)C(C#N)=C1 LNGWRTKJZCBXGT-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- QGBSISYHAICWAH-UHFFFAOYSA-N dicyandiamide Chemical compound NC(N)=NC#N QGBSISYHAICWAH-UHFFFAOYSA-N 0.000 abstract 2
- ATCGGEJZONJOCL-UHFFFAOYSA-N 6-(2,5-dichlorophenyl)-1,3,5-triazine-2,4-diamine Chemical compound NC1=NC(N)=NC(C=2C(=CC=C(Cl)C=2)Cl)=N1 ATCGGEJZONJOCL-UHFFFAOYSA-N 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
- C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
- C07D251/18—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom with nitrogen atoms directly attached to the two other ring carbon atoms, e.g. guanamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
UN PROCEDIMIENTO PARA PREPARAR DERIVADOS DE BENZOGUANAMINA REPRESENTADOS POR LA FORMULA:EN EL QUE SE HACEN REACCIONAR 2,5-DICLOROBENZONITRILO Y DICIANDIAMIDA EN UN DISOLVENTE DE ALCOHOL TERCIARIO Y EN PRESENCIA DE UN CATALIZADOR ALCALINO. COMO ALCOHOL TERCIARIO SE EMPLEAN PREFERIBLEMENTE ALCOHOL TERC-BUTILICO Y ALCOHOL TERC-AMILICO, LLEVANDOSE A CABO LA REACCION A UNA TEMPERATURA DEL ORDEN DE 80GC DURANTE UN PERIODO DE TIEMPO DE APROXIMADAMENTE 8 A 12 HORAS. LOS COMPUESTOS OBTENIDOS SON UTILES COMO FARMACOS ANTIULCERAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61135196A JPH072726B2 (ja) | 1986-06-10 | 1986-06-10 | ベンゾグアナミン誘導体の製法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2005249A6 true ES2005249A6 (es) | 1989-03-01 |
Family
ID=15146092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8701678A Expired ES2005249A6 (es) | 1986-06-10 | 1987-06-08 | Un procedimiento para preparar derivados de benzoguanamina. |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPH072726B2 (es) |
| KR (1) | KR950005204B1 (es) |
| AT (1) | AT395713B (es) |
| CA (1) | CA1290754C (es) |
| ES (1) | ES2005249A6 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150362A (en) * | 1997-12-12 | 2000-11-21 | Henkin; Jack | Triazine angiogenesis inhibitors |
| KR101289575B1 (ko) * | 2012-09-07 | 2013-07-24 | 박충만 | 로스트 치킨의 제조방법 |
| CN106187928B (zh) * | 2016-08-02 | 2019-06-07 | 安徽省逸欣铭医药科技有限公司 | 一种马来酸伊索拉定的制备方法 |
| KR101896105B1 (ko) * | 2017-08-28 | 2018-09-07 | 최용선 | 말이 형태의 식품 제형의 제조 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1441904A (en) * | 1974-02-18 | 1976-07-07 | Nippon Shinyaku Co Ltd | Benzoguanamine derivatives |
| JPS5925765B2 (ja) * | 1981-08-04 | 1984-06-21 | 日本新薬株式会社 | 消化性潰瘍治療剤 |
-
1986
- 1986-06-10 JP JP61135196A patent/JPH072726B2/ja not_active Expired - Lifetime
-
1987
- 1987-06-03 CA CA000538701A patent/CA1290754C/en not_active Expired - Lifetime
- 1987-06-08 ES ES8701678A patent/ES2005249A6/es not_active Expired
- 1987-06-09 AT AT0144887A patent/AT395713B/de not_active IP Right Cessation
- 1987-06-10 KR KR1019870005855A patent/KR950005204B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATA144887A (de) | 1992-07-15 |
| JPS62292771A (ja) | 1987-12-19 |
| KR950005204B1 (ko) | 1995-05-19 |
| JPH072726B2 (ja) | 1995-01-18 |
| KR880000411A (ko) | 1988-03-25 |
| AT395713B (de) | 1993-02-25 |
| CA1290754C (en) | 1991-10-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GR3021835T3 (en) | Process for preparing alkyl polyglycosides. | |
| EP0107335A1 (en) | Process for the preparation of p-nitrosodiphenylamine | |
| ES2005249A6 (es) | Un procedimiento para preparar derivados de benzoguanamina. | |
| GB2023143A (en) | Continuous Cyanoethylation Process | |
| US3969466A (en) | Preparation of hydrazodicarbonamide | |
| GB1572316A (en) | Process for preparing 5-(4-hydroxyphenyl)hydantion | |
| EP0248586A3 (en) | Process for producing amidine sulfonic acid intermediates for guanidines | |
| AU7055596A (en) | Process for preparing 1-substituted pyrrole-3-carboxylic acid derivatives | |
| US4997939A (en) | Process for preparing adenine | |
| DE3169902D1 (en) | Process for preparing thiochloroformiates | |
| KR950005793A (ko) | 광학활성 2- 노르보르난온의 제조방법 | |
| EP0519083A4 (en) | Process for producing hexahydropyridazine-1,2-dicarboxylic acid derivative | |
| US4861883A (en) | Process for preparing adenine | |
| US5688969A (en) | Process for the preparation of thiophene-2-5-dicarboxylic acid and the dichloride thereof | |
| EP0649836A1 (en) | Processes for the preparation of N-(long-chain acyl)amino acid and salt thereof, and intermediate amidonitrile and process for the preparation thereof | |
| US3127399A (en) | Tablb ii | |
| US5189195A (en) | Process for producing stable, low odor S,S,S-tributylphosphorotrithioate | |
| ES451930A1 (es) | Un procedimiento para la sintesis de 2,3-dimetoxi-5-metil- 1,4 - benzoquinonas 6-sustituidos. | |
| GB2160204A (en) | Preparation of N-methyl-1-alkylthio-2-nitroethenamines | |
| GB2170806A (en) | N-(b-mercapto-iso-butyryl)proline, derivatives and a process for their preparation | |
| JPS5731682A (en) | Preparation of alkylene carbonate | |
| US3946030A (en) | 2-Mercaptoarylthioazole production | |
| US4496529A (en) | Preparation of metal cyanates from alkyl carbamates | |
| FI881250A7 (fi) | Foerfarande foer framstaellning av aminoacylaniliner. | |
| US2927117A (en) | Production of 3-indoleacetonitrile from indole |