ES2002728A6 - Antibiotics - Google Patents

Antibiotics

Info

Publication number
ES2002728A6
ES2002728A6 ES8601355A ES8601355A ES2002728A6 ES 2002728 A6 ES2002728 A6 ES 2002728A6 ES 8601355 A ES8601355 A ES 8601355A ES 8601355 A ES8601355 A ES 8601355A ES 2002728 A6 ES2002728 A6 ES 2002728A6
Authority
ES
Spain
Prior art keywords
bbm
esperamicin
produced
substances
antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601355A
Other languages
Spanish (es)
Inventor
Jerzy Golik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES2002728A6 publication Critical patent/ES2002728A6/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03—Actinomadura

Abstract

There is provided new antitumor antibiotic substances designated herein as BBM-1675C and BBM-1675D, said substances being produced by selective chemical hydrolysis of the bioactive components BBM-1675A1 (esperamicin A1) or BBM-1675A2 (esperamicin A2) produced from Actinomadura verrucosospora. BBM 1675C and BBM 1675D have molecular weights of approx 855 and 695 respectively.
ES8601355A 1985-08-27 1986-08-26 Antibiotics Expired ES2002728A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77033585A 1985-08-27 1985-08-27

Publications (1)

Publication Number Publication Date
ES2002728A6 true ES2002728A6 (en) 1988-10-01

Family

ID=25088206

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601355A Expired ES2002728A6 (en) 1985-08-27 1986-08-26 Antibiotics

Country Status (26)

Country Link
JP (2) JPH0733393B2 (en)
KR (1) KR920010226B1 (en)
AT (1) AT392971B (en)
AU (1) AU604464B2 (en)
BE (1) BE905332A (en)
CA (1) CA1307256C (en)
CH (1) CH668598A5 (en)
CY (1) CY1676A (en)
DE (1) DE3629052C2 (en)
DK (1) DK170671B1 (en)
ES (1) ES2002728A6 (en)
FI (1) FI83422C (en)
FR (1) FR2586686B1 (en)
GB (1) GB2179649A (en)
GR (1) GR862160B (en)
HK (1) HK793A (en)
HU (1) HU197915B (en)
IE (1) IE59204B1 (en)
IL (1) IL79519A0 (en)
IT (1) IT1229176B (en)
LU (1) LU86562A1 (en)
NL (1) NL8602165A (en)
PT (1) PT83261B (en)
SE (2) SE469632B (en)
SG (1) SG109692G (en)
ZA (1) ZA865796B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3752355T2 (en) * 1987-01-30 2002-12-05 American Cyanamid Co Dihydro derivatives of type LL-E33288 antibiotics
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CA2039789A1 (en) * 1990-04-27 1991-10-28 Samuel J. Danishefsky Calicheamicinone, derivatives and analogs thereof and methods of making the same
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148023A1 (en) * 1981-12-04 1983-06-09 Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer Heating boiler for hot flue gases
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions
NZ208013A (en) * 1983-05-16 1987-07-31 Bristol Myers Co Antitumour antibiotic bbm-1675 and production by cultivating actinomadura verrucosospora
JPS606194A (en) * 1983-06-23 1985-01-12 Meiji Seika Kaisha Ltd Novel antibiotic substance sf-2288 and its preparation
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Also Published As

Publication number Publication date
SE8603597D0 (en) 1986-08-26
HUT44035A (en) 1988-01-28
AU6175186A (en) 1987-03-05
DE3629052C2 (en) 1995-09-28
KR870002269A (en) 1987-03-30
DK406086A (en) 1987-02-28
GB8620118D0 (en) 1986-10-01
NL8602165A (en) 1987-03-16
LU86562A1 (en) 1987-03-06
IL79519A0 (en) 1986-10-31
DK170671B1 (en) 1995-11-27
GB2179649B (en) 1989-10-25
FI863405A (en) 1987-02-28
IT1229176B (en) 1991-07-23
SE9200428D0 (en) 1992-02-13
CA1307256C (en) 1992-09-08
PT83261B (en) 1989-05-12
FR2586686A1 (en) 1987-03-06
BE905332A (en) 1987-02-26
SE9200428L (en) 1993-08-14
HU197915B (en) 1989-06-28
FI83422B (en) 1991-03-28
FR2586686B1 (en) 1990-02-02
KR920010226B1 (en) 1992-11-21
SG109692G (en) 1992-12-24
IT8621527A0 (en) 1986-08-26
CY1676A (en) 1993-10-10
AU604464B2 (en) 1990-12-20
JPH0733393B2 (en) 1995-04-12
DK406086D0 (en) 1986-08-26
JPS62116589A (en) 1987-05-28
IE59204B1 (en) 1994-01-26
DE3629052A1 (en) 1987-05-07
SE8603597L (en) 1987-02-28
FI83422C (en) 1991-07-10
HK793A (en) 1993-01-15
GR862160B (en) 1986-12-31
AT392971B (en) 1991-07-25
CH668598A5 (en) 1989-01-13
GB2179649A (en) 1987-03-11
FI863405A0 (en) 1986-08-22
IE862280L (en) 1987-02-27
PT83261A (en) 1986-09-01
SE469632B (en) 1993-08-09
ZA865796B (en) 1987-04-29
JPH07233186A (en) 1995-09-05
ATA231786A (en) 1990-12-15

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